| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mifepristone_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.254183 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.142532 |
| TMSB10 | thymosin beta 10 | 0.140537 |
| AHNAK | AHNAK nucleoprotein | 0.113888 |
| VIM | vimentin | 0.0968258 |
| ENO1 | enolase 1, (alpha) | 0.0823799 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0755802 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0719232 |
| CALR | calreticulin | 0.0701728 |
| MT2A | metallothionein 2A | 0.0691176 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0660607 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.058325 |
| COL5A1 | collagen, type V, alpha 1 | 0.0564655 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0564009 |
| C1D | C1D nuclear receptor corepressor | 0.0546549 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0545913 |
| POTEF | POTE ankyrin domain family, member F | 0.050295 |
| LDHA | lactate dehydrogenase A | 0.0461557 |
| PRSS23 | protease, serine, 23 | 0.0446165 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0445651 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0424295 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0409014 |
| PTMA | prothymosin, alpha | 0.0403464 |
| THBS2 | thrombospondin 2 | 0.0400332 |
| B2M | beta-2-microglobulin | 0.0396086 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0394008 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0390527 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0388575 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0381906 |
| ANXA1 | annexin A1 | 0.0379539 |
| RPL23 | ribosomal protein L23 | 0.0364962 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0355734 |
| RPS3 | ribosomal protein S3 | 0.0335141 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0334847 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0332522 |
| PODXL | podocalyxin-like | 0.032878 |
| FLNA | filamin A, alpha | 0.0324076 |
| FTL | ferritin, light polypeptide | 0.0317499 |
| LOXL2 | lysyl oxidase-like 2 | 0.0304111 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0304056 |
| EZR | ezrin | 0.0302464 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0298945 |
| PKM | pyruvate kinase, muscle | 0.0290146 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0290036 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0284719 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.02819 |
| ACTG1 | actin gamma 1 | 0.0279846 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0277089 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.026565 |
| CD109 | CD109 molecule | 0.0264965 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0260718 |
| CSTB | cystatin B (stefin B) | 0.0255626 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0252512 |
| S100A6 | S100 calcium binding protein A6 | 0.0249967 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0245413 |
| L1CAM | L1 cell adhesion molecule | 0.0241979 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0236954 |
| TPM3 | tropomyosin 3 | 0.0235683 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0233924 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0232665 |
| PCBP2 | poly(rC) binding protein 2 | 0.0232585 |
| RPL37A | ribosomal protein L37a | 0.0225542 |
| DENND4C | DENN/MADD domain containing 4C | 0.0223687 |
| RPL3 | ribosomal protein L3 | 0.0219624 |
| MCL1 | myeloid cell leukemia 1 | 0.0218625 |
| RPS12 | ribosomal protein S12 | 0.0215514 |
| STK10 | serine/threonine kinase 10 | 0.0212989 |
| HAUS6 | HAUS augmin-like complex, subunit 6 | 0.0212276 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0210527 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0207578 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0206944 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.020607 |
| CRMP1 | collapsin response mediator protein 1 | 0.0205222 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0201157 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.020023 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0198256 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0197964 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0197595 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0196739 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0195964 |
| GOLGA2 | golgin A2 | 0.01946 |
| LOX | lysyl oxidase | 0.0194153 |
| FAM13A | family with sequence similarity 13, member A | 0.0190469 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0189705 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0188855 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0188009 |
| RPS19 | ribosomal protein S19 | 0.01837 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.01819 |
| APP | amyloid beta (A4) precursor protein | 0.0180627 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0180288 |
| S100A11 | S100 calcium binding protein A11 | 0.0179846 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0174873 |
| RPL27 | ribosomal protein L27 | 0.0172941 |
| YBX1 | Y box binding protein 1 | 0.0172173 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0172151 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0170968 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0170602 |
| ACLY | ATP citrate lyase | 0.0170102 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0170037 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0170002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.285877 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.251865 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128695 |
| PLAT | plasminogen activator, tissue | -0.113729 |
| CD44 | CD44 molecule (Indian blood group) | -0.101802 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0701087 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0665933 |
| S100A10 | S100 calcium binding protein A10 | -0.0659348 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0609831 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0561156 |
| UBC | ubiquitin C | -0.0534306 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0532176 |
| STC1 | stanniocalcin 1 | -0.050894 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0475151 |
| RUNX1 | runt-related transcription factor 1 | -0.0469324 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0451407 |
| CD99 | CD99 molecule | -0.0440902 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0437653 |
| SBF2 | SET binding factor 2 | -0.0424414 |
| MB21D2 | Mab-21 domain containing 2 | -0.0420864 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0414289 |
| CCND1 | cyclin D1 | -0.0400276 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.039596 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.038289 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0381298 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0375391 |
| CDK6 | cyclin-dependent kinase 6 | -0.0374966 |
| CENPF | centromere protein F, 350/400kDa | -0.0369107 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0367884 |
| TAOK1 | TAO kinase 1 | -0.0361607 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0359941 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0358186 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.035763 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0357177 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0352857 |
| HIP1 | huntingtin interacting protein 1 | -0.0351291 |
| MAP4 | microtubule-associated protein 4 | -0.0351015 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0343577 |
| PTK2 | protein tyrosine kinase 2 | -0.0341651 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0325743 |
| RASA2 | RAS p21 protein activator 2 | -0.0323098 |
| SMYD3 | SET and MYND domain containing 3 | -0.0312814 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0308819 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0305882 |
| RAI14 | retinoic acid induced 14 | -0.0304354 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0303301 |
| PARD3 | par-3 family cell polarity regulator | -0.0300333 |
| TRIM56 | tripartite motif containing 56 | -0.0293356 |
| CANX | calnexin | -0.0288175 |
| FNBP1 | formin binding protein 1 | -0.0285989 |
| EHBP1 | EH domain binding protein 1 | -0.0283797 |
| GLIS3 | GLIS family zinc finger 3 | -0.0283208 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0282474 |
| VDAC1 | voltage-dependent anion channel 1 | -0.028046 |
| CUX1 | cut-like homeobox 1 | -0.028025 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0279276 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0278894 |
| MX2 | MX dynamin-like GTPase 2 | -0.0275778 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0273983 |
| NAV1 | neuron navigator 1 | -0.0273955 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0273547 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0273165 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0272984 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0272492 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0271681 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0270868 |
| OGA | O-GlcNAcase | -0.0269873 |
| ARFGEF3 | ARFGEF family member 3 | -0.0265812 |
| SETD5 | SET domain containing 5 | -0.026503 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0264406 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0263449 |
| FBN1 | fibrillin 1 | -0.0263103 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0262014 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0260807 |
| SPAG9 | sperm associated antigen 9 | -0.0260188 |
| MEIS2 | Meis homeobox 2 | -0.0258185 |
| RAB10 | RAB10, member RAS oncogene family | -0.0257632 |
| FUS | FUS RNA binding protein | -0.0257627 |
| CLTC | clathrin, heavy chain (Hc) | -0.0257504 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0252953 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0252896 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0249541 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0249421 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0248864 |
| COL3A1 | collagen, type III, alpha 1 | -0.0246728 |
| ERBIN | erbb2 interacting protein | -0.024638 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0246291 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.024601 |
| IER3 | immediate early response 3 | -0.0244394 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0243291 |
| FNIP1 | folliculin interacting protein 1 | -0.0242578 |
| KIFAP3 | kinesin-associated protein 3 | -0.0241625 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0240779 |
| XPO1 | exportin 1 | -0.0240236 |
| IL6ST | interleukin 6 signal transducer | -0.0240101 |
| NF1 | neurofibromin 1 | -0.0238818 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0238256 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0238134 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0237015 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0236819 |
