| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.180389 |
| DST | dystonin | 0.171779 |
| PLIN2 | perilipin 2 | 0.141551 |
| AHNAK | AHNAK nucleoprotein | 0.118314 |
| ENO1 | enolase 1, (alpha) | 0.117518 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.108663 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.108286 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.106696 |
| TMSB4X | thymosin beta 4, X-linked | 0.103812 |
| POTEF | POTE ankyrin domain family, member F | 0.0989259 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0921258 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0898972 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0885425 |
| ACTG1 | actin gamma 1 | 0.0848503 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0813392 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0757455 |
| EZR | ezrin | 0.0757258 |
| APP | amyloid beta (A4) precursor protein | 0.0740923 |
| TXNIP | thioredoxin interacting protein | 0.0708124 |
| PGK1 | phosphoglycerate kinase 1 | 0.0704392 |
| FMNL2 | formin-like 2 | 0.0701161 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0682458 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0680981 |
| LDHA | lactate dehydrogenase A | 0.064797 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0597324 |
| SQSTM1 | sequestosome 1 | 0.0595582 |
| XPO1 | exportin 1 | 0.0582826 |
| CANX | calnexin | 0.0576571 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0561792 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0558575 |
| CENPF | centromere protein F, 350/400kDa | 0.0558353 |
| ADAR | adenosine deaminase, RNA-specific | 0.0553509 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0533913 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0526194 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0522138 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0521319 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0518538 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0509702 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0503574 |
| OGA | O-GlcNAcase | 0.0499798 |
| UBC | ubiquitin C | 0.0489901 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.047818 |
| ZNF292 | zinc finger protein 292 | 0.0477691 |
| SPAG9 | sperm associated antigen 9 | 0.0473118 |
| ANXA1 | annexin A1 | 0.0467179 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0466946 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0461988 |
| CAPRIN2 | caprin family member 2 | 0.0455808 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0452319 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0447747 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0446486 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.043996 |
| ANLN | anillin, actin binding protein | 0.0439719 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0435321 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0428837 |
| HSPA8 | heat shock 70kDa protein 8 | 0.04287 |
| MATR3 | matrin 3 | 0.0420132 |
| PCBP2 | poly(rC) binding protein 2 | 0.0420105 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0417496 |
| MKI67 | marker of proliferation Ki-67 | 0.0410821 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.041081 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0407678 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0405139 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.040233 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0389807 |
| TPR | translocated promoter region, nuclear basket protein | 0.0388609 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0386936 |
| EREG | epiregulin | 0.0382125 |
| IPO7 | importin 7 | 0.0378906 |
| RBM39 | RNA binding motif protein 39 | 0.0377036 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0360972 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0358136 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.035654 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0344454 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0343093 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0338892 |
| KLF6 | Kruppel-like factor 6 | 0.0333504 |
| ZNF217 | zinc finger protein 217 | 0.0332861 |
| RAD51B | RAD51 paralog B | 0.033203 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0330466 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0327944 |
| SFPQ | splicing factor proline/glutamine-rich | 0.032786 |
| SRPK2 | SRSF protein kinase 2 | 0.0326537 |
| NCOR1 | nuclear receptor corepressor 1 | 0.032568 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0324815 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0324216 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0323458 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0323218 |
| PRELID2 | PRELI domain containing 2 | 0.0323026 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0320101 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0317867 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.031734 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0315797 |
| SEPTIN7 | septin 7 | 0.0315129 |
| SET | SET nuclear proto-oncogene | 0.031354 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0310648 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0307555 |
| RPL4 | ribosomal protein L4 | 0.0307194 |
| SLK | STE20-like kinase | 0.0306904 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0305005 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.153032 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109801 |
| TP63 | tumor protein p63 | -0.0808709 |
| MT2A | metallothionein 2A | -0.076321 |
| EGR1 | early growth response 1 | -0.0735553 |
| RPL35A | ribosomal protein L35a | -0.0676639 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0659054 |
| FTL | ferritin, light polypeptide | -0.0653295 |
| RPS8 | ribosomal protein S8 | -0.0605048 |
| RPS19 | ribosomal protein S19 | -0.058228 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0510858 |
| HMGA1 | high mobility group AT-hook 1 | -0.0505157 |
| TXNRD1 | thioredoxin reductase 1 | -0.0494827 |
| RPS6 | ribosomal protein S6 | -0.0487548 |
| RPL12 | ribosomal protein L12 | -0.0468172 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0463547 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0442743 |
| RPL26 | ribosomal protein L26 | -0.0424126 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0399937 |
| CMIP | c-Maf inducing protein | -0.0395125 |
| RPL36 | ribosomal protein L36 | -0.0386869 |
| RPLP1 | ribosomal protein, large, P1 | -0.0370288 |
| RPS3 | ribosomal protein S3 | -0.0362606 |
| RPL23 | ribosomal protein L23 | -0.0359644 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0348959 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0334118 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0331502 |
| RPL19 | ribosomal protein L19 | -0.0328408 |
| PTMA | prothymosin, alpha | -0.030914 |
| RPL35 | ribosomal protein L35 | -0.0305093 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0302623 |
| RPS29 | ribosomal protein S29 | -0.0297281 |
| RPL31 | ribosomal protein L31 | -0.0293508 |
| RPL5 | ribosomal protein L5 | -0.0293379 |
| RPL37A | ribosomal protein L37a | -0.0284199 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0275904 |
| RPL34 | ribosomal protein L34 | -0.027467 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0268357 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0267334 |
| SEC24A | SEC24 family member A | -0.0264197 |
| RPS12 | ribosomal protein S12 | -0.0261444 |
| RPS27 | ribosomal protein S27 | -0.02561 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0251002 |
| RPL9 | ribosomal protein L9 | -0.0242302 |
| RPS17 | ribosomal protein S17 | -0.0240957 |
| RPL37 | ribosomal protein L37 | -0.023991 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0239133 |
| RPL18 | ribosomal protein L18 | -0.0236621 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.023404 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0233859 |
| RPS14 | ribosomal protein S14 | -0.0225407 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0222529 |
| RPL28 | ribosomal protein L28 | -0.0221086 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0217015 |
| RPS13 | ribosomal protein S13 | -0.0215532 |
| RPLP2 | ribosomal protein, large, P2 | -0.020576 |
| RPS24 | ribosomal protein S24 | -0.0202213 |
| TGM2 | transglutaminase 2 | -0.0198732 |
| RPS27A | ribosomal protein S27a | -0.0190525 |
| PFN1 | profilin 1 | -0.0187341 |
| RASAL2 | RAS protein activator like 2 | -0.0182027 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0180496 |
| RACK1 | receptor for activated C kinase 1 | -0.0179283 |
| EPHA4 | EPH receptor A4 | -0.0179096 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0178761 |
| RPL36A | ribosomal protein L36a | -0.0175395 |
| EHBP1 | EH domain binding protein 1 | -0.0175239 |
| PDE10A | phosphodiesterase 10A | -0.0173388 |
| NEK10 | NIMA-related kinase 10 | -0.0172955 |
| RPS16 | ribosomal protein S16 | -0.0172314 |
| TAPBP | TAP binding protein (tapasin) | -0.0172207 |
| RPL27 | ribosomal protein L27 | -0.0171832 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0171327 |
| OSMR | oncostatin M receptor | -0.0168115 |
| RPS5 | ribosomal protein S5 | -0.0166033 |
| RPS10 | ribosomal protein S10 | -0.016358 |
| RPL11 | ribosomal protein L11 | -0.0161687 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0161521 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0160693 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0159969 |
| TBCA | tubulin folding cofactor A | -0.0159775 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -0.015676 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0156404 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0155241 |
| TMEM41B | transmembrane protein 41B | -0.014997 |
| S100A9 | S100 calcium binding protein A9 | -0.014972 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0148555 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0144673 |
| YBX3 | Y box binding protein 3 | -0.0142629 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0142134 |
| PYGL | phosphorylase, glycogen, liver | -0.0141706 |
| AHI1 | Abelson helper integration site 1 | -0.0141343 |
| MYADM | myeloid-associated differentiation marker | -0.0136084 |
| SMAD3 | SMAD family member 3 | -0.013599 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0135976 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0135538 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0134813 |
| HBEGF | heparin-binding EGF-like growth factor | -0.0134266 |
| UPP1 | uridine phosphorylase 1 | -0.0133161 |
| RPL38 | ribosomal protein L38 | -0.0132864 |
