| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.296354 |
| MT2A | metallothionein 2A | 0.159169 |
| MCL1 | myeloid cell leukemia 1 | 0.145268 |
| CES1 | carboxylesterase 1 | 0.117634 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.11233 |
| LAMA4 | laminin, alpha 4 | 0.08831 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0849132 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0811178 |
| DSPP | dentin sialophosphoprotein | 0.0774835 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0716336 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0693899 |
| RNF149 | ring finger protein 149 | 0.0688733 |
| FAM13A | family with sequence similarity 13, member A | 0.0676223 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0632931 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0564287 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0560942 |
| ENO1 | enolase 1, (alpha) | 0.0553902 |
| HYOU1 | hypoxia up-regulated 1 | 0.0540905 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0527163 |
| RNF145 | ring finger protein 145 | 0.0519284 |
| FRY | furry homolog (Drosophila) | 0.0508644 |
| TES | testin LIM domain protein | 0.048616 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0472642 |
| POTEF | POTE ankyrin domain family, member F | 0.0470105 |
| GRAMD1B | GRAM domain containing 1B | 0.0469195 |
| MKI67 | marker of proliferation Ki-67 | 0.0460682 |
| PCBP2 | poly(rC) binding protein 2 | 0.0452545 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.044313 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0433409 |
| ATP11A | ATPase, class VI, type 11A | 0.0424121 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0416599 |
| LDHA | lactate dehydrogenase A | 0.041567 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0410254 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0407621 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0407532 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0407367 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0393295 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0388285 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0372298 |
| AHNAK | AHNAK nucleoprotein | 0.0364781 |
| TPM3 | tropomyosin 3 | 0.0357183 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0326849 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0326734 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0320833 |
| SQOR | sulfide quinone oxidoreductase | 0.0317244 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0316879 |
| YAP1 | Yes-associated protein 1 | 0.0314778 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0309343 |
| SLTM | SAFB-like, transcription modulator | 0.0309132 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0301155 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0296493 |
| PYGL | phosphorylase, glycogen, liver | 0.0293518 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0289651 |
| DNER | delta/notch-like EGF repeat containing | 0.0283008 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.027931 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0271119 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0267091 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0265586 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0263173 |
| RPL3 | ribosomal protein L3 | 0.0262953 |
| ANXA5 | annexin A5 | 0.0261929 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0261804 |
| PLEC | plectin | 0.025544 |
| S100P | S100 calcium binding protein P | 0.0255044 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0253993 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0252712 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0252501 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0252357 |
| RUNX1 | runt-related transcription factor 1 | 0.0251584 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0246905 |
| WDR26 | WD repeat domain 26 | 0.0245386 |
| TMEM45B | transmembrane protein 45B | 0.0241615 |
| MLKL | mixed lineage kinase domain-like | 0.024126 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0240236 |
| SYAP1 | synapse associated protein 1 | 0.0239931 |
| STK24 | serine/threonine kinase 24 | 0.0239507 |
| ATP13A3 | ATPase type 13A3 | 0.0237106 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0236351 |
| EFNA5 | ephrin-A5 | 0.0236257 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0233842 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0230714 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0230135 |
| SCEL | sciellin | 0.0228301 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0224559 |
| RPL4 | ribosomal protein L4 | 0.0224146 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0221808 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0221357 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0220123 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0217285 |
| XDH | xanthine dehydrogenase | 0.0216135 |
| MSN | moesin | 0.0215888 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0215234 |
| TOP1 | topoisomerase (DNA) I | 0.0214882 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0213314 |
| METTL9 | methyltransferase like 9 | 0.0212648 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0212138 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0210642 |
| ZNF292 | zinc finger protein 292 | 0.0210226 |
| IRS2 | insulin receptor substrate 2 | 0.0209956 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0208219 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.282674 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.280408 |
| TMSB10 | thymosin beta 10 | -0.11722 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0937203 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0818877 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0767077 |
| FTL | ferritin, light polypeptide | -0.0704118 |
| PTMA | prothymosin, alpha | -0.070308 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0615383 |
| H1-0 | H1.0 linker histone | -0.0593811 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0575881 |
| TXNRD1 | thioredoxin reductase 1 | -0.056422 |
| RPS24 | ribosomal protein S24 | -0.0550678 |
| INTS6 | integrator complex subunit 6 | -0.0533685 |
| NDRG1 | N-myc downstream regulated 1 | -0.0530917 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0530317 |
| RPL35A | ribosomal protein L35a | -0.0517266 |
| EGFR | epidermal growth factor receptor | -0.0501443 |
| ASPH | aspartate beta-hydroxylase | -0.0499374 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0466526 |
| EGR1 | early growth response 1 | -0.0457902 |
| IER3 | immediate early response 3 | -0.0457354 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0441972 |
| S100A10 | S100 calcium binding protein A10 | -0.0434844 |
| MYO1E | myosin IE | -0.0430731 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0429112 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0416207 |
| MAP7 | microtubule-associated protein 7 | -0.0415864 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0408082 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0403977 |
| RPL34 | ribosomal protein L34 | -0.0402603 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0397983 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0392734 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0390397 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0374069 |
| PDE8A | phosphodiesterase 8A | -0.0368429 |
| HOMER1 | homer scaffolding protein 1 | -0.0343838 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0343384 |
| RPLP1 | ribosomal protein, large, P1 | -0.0340107 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0338772 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0338464 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0337236 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0330311 |
| RPS25 | ribosomal protein S25 | -0.0327857 |
| NABP1 | nucleic acid binding protein 1 | -0.0326493 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0325926 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0315545 |
| GM2A | GM2 ganglioside activator | -0.0313404 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.031242 |
| RPS8 | ribosomal protein S8 | -0.0310068 |
| STC1 | stanniocalcin 1 | -0.0308669 |
| KIAA1217 | KIAA1217 | -0.0305686 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0305032 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0299562 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0297572 |
| RPL31 | ribosomal protein L31 | -0.0294475 |
| RNF213 | ring finger protein 213 | -0.0290999 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0290068 |
| RPLP0 | ribosomal protein, large, P0 | -0.0288887 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0288105 |
| LAMC2 | laminin, gamma 2 | -0.0283779 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.028186 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0276237 |
| RPS6 | ribosomal protein S6 | -0.0274397 |
| B2M | beta-2-microglobulin | -0.0273338 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0273172 |
| GNAS | GNAS complex locus | -0.0272281 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0266942 |
| ABLIM1 | actin binding LIM protein 1 | -0.0262424 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0260052 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0259644 |
| HMGA1 | high mobility group AT-hook 1 | -0.0259318 |
| GPC6 | glypican 6 | -0.0259272 |
| HLA-B | major histocompatibility complex, class I, B | -0.0255358 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0253856 |
| DENND4A | DENN/MADD domain containing 4A | -0.0252275 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0251029 |
| CCND1 | cyclin D1 | -0.0242174 |
| TNS3 | tensin 3 | -0.0234829 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0233905 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0232741 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0231499 |
| UVRAG | UV radiation resistance associated | -0.0230222 |
| JAK1 | Janus kinase 1 | -0.0227343 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0226124 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0223814 |
| CST3 | cystatin C | -0.0219153 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0217314 |
| RPL19 | ribosomal protein L19 | -0.0215126 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.021417 |
| RPL12 | ribosomal protein L12 | -0.0214095 |
| RPS27A | ribosomal protein S27a | -0.0213354 |
| RPL37A | ribosomal protein L37a | -0.0211982 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0208721 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0208368 |
| SP100 | SP100 nuclear antigen | -0.0207208 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0204404 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0203918 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0201819 |
| RPL8 | ribosomal protein L8 | -0.0201352 |
