| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLIN2 | perilipin 2 | 0.217217 |
| PCBP2 | poly(rC) binding protein 2 | 0.21089 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.192827 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.130234 |
| FN1 | fibronectin 1 | 0.129871 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.111224 |
| FAM13A | family with sequence similarity 13, member A | 0.0967305 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0952195 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0852821 |
| AHNAK | AHNAK nucleoprotein | 0.0818211 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0792879 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0775763 |
| ENO1 | enolase 1, (alpha) | 0.0732054 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0724485 |
| ASPH | aspartate beta-hydroxylase | 0.0703599 |
| LDHA | lactate dehydrogenase A | 0.0683739 |
| POTEF | POTE ankyrin domain family, member F | 0.0623575 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0620485 |
| MCL1 | myeloid cell leukemia 1 | 0.0616898 |
| FLNB | filamin B, beta | 0.0602928 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0585581 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0582104 |
| NAV2 | neuron navigator 2 | 0.0574542 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0560417 |
| MAP1B | microtubule-associated protein 1B | 0.0559799 |
| ANXA1 | annexin A1 | 0.0554252 |
| LOX | lysyl oxidase | 0.0550733 |
| CD44 | CD44 molecule (Indian blood group) | 0.0527991 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0525895 |
| ITGAV | integrin, alpha V | 0.051632 |
| DST | dystonin | 0.0514708 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0512091 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0504157 |
| RAD51B | RAD51 paralog B | 0.0488046 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0486485 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0482204 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0477002 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0476581 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0473246 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0463404 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0462268 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0461484 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0460785 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0454281 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.045377 |
| MEF2A | myocyte enhancer factor 2A | 0.0451844 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0450758 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.044919 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0448795 |
| RPL3 | ribosomal protein L3 | 0.0435707 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0430592 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0417547 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0412573 |
| CA12 | carbonic anhydrase XII | 0.041092 |
| ADD3 | adducin 3 (gamma) | 0.0409989 |
| GPC6 | glypican 6 | 0.0408412 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0403849 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0401786 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0401101 |
| ANGPTL4 | angiopoietin-like 4 | 0.0397838 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0397552 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0392944 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.039233 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0389048 |
| ATP13A3 | ATPase type 13A3 | 0.0383214 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0375831 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.037106 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0368179 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.03658 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0364405 |
| HELZ | helicase with zinc finger | 0.0362762 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0361981 |
| VMP1 | vacuole membrane protein 1 | 0.0357909 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.035559 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0351109 |
| TGM2 | transglutaminase 2 | 0.0348353 |
| CUL4B | cullin 4B | 0.0347338 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0345594 |
| OPTN | optineurin | 0.0344725 |
| MYOF | myoferlin | 0.0343298 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0331066 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0329733 |
| SIK3 | SIK family kinase 3 | 0.0323889 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0321237 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0314684 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0314394 |
| RUNX2 | runt-related transcription factor 2 | 0.0312912 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.031283 |
| ANKRD28 | ankyrin repeat domain 28 | 0.031247 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0310934 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0310342 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0310341 |
| CCNL1 | cyclin L1 | 0.0309247 |
| ANXA2 | annexin A2 | 0.030388 |
| NAV1 | neuron navigator 1 | 0.030186 |
| SETD5 | SET domain containing 5 | 0.0291671 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0289066 |
| USP34 | ubiquitin specific peptidase 34 | 0.0287723 |
| APP | amyloid beta (A4) precursor protein | 0.0286174 |
| CD109 | CD109 molecule | 0.0284876 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.137954 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.105488 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104174 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0877172 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0875658 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0864369 |
| IER3 | immediate early response 3 | -0.0861848 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0742007 |
| RPLP1 | ribosomal protein, large, P1 | -0.0711858 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0645272 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.063259 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0593931 |
| OSMR | oncostatin M receptor | -0.0583633 |
| RPL35A | ribosomal protein L35a | -0.0545418 |
| GLCCI1 | glucocorticoid induced 1 | -0.0545029 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0530861 |
| RPL34 | ribosomal protein L34 | -0.051013 |
| SMAD3 | SMAD family member 3 | -0.0487512 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0486692 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0476711 |
| RPS24 | ribosomal protein S24 | -0.0475647 |
| RPS6 | ribosomal protein S6 | -0.0460915 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0451877 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0447389 |
| RPS19 | ribosomal protein S19 | -0.0442619 |
| FNBP1 | formin binding protein 1 | -0.044 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0436984 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0435439 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0425867 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0399486 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0399437 |
| RPS21 | ribosomal protein S21 | -0.0383901 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0382934 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0376428 |
| ANTXR2 | anthrax toxin receptor 2 | -0.035875 |
| CDCP1 | CUB domain containing protein 1 | -0.0356594 |
| KYNU | kynureninase | -0.0355509 |
| DENND4A | DENN/MADD domain containing 4A | -0.0353255 |
| RPL32 | ribosomal protein L32 | -0.035303 |
| RPL36 | ribosomal protein L36 | -0.034207 |
| GOLGA4 | golgin A4 | -0.0340974 |
| RPS8 | ribosomal protein S8 | -0.0340316 |
| FRMD5 | FERM domain containing 5 | -0.0339859 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.033514 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0324189 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0323811 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0318449 |
| RPS29 | ribosomal protein S29 | -0.0317752 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0316497 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0312205 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311674 |
| ZNF804A | zinc finger protein 804A | -0.0310969 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0310653 |
| RPL37A | ribosomal protein L37a | -0.0310143 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0308461 |
| RPL38 | ribosomal protein L38 | -0.0308198 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0308107 |
| GNAS | GNAS complex locus | -0.0307167 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0304885 |
| RPL37 | ribosomal protein L37 | -0.0304367 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0302974 |
| VIM | vimentin | -0.0300723 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0297591 |
| RPL11 | ribosomal protein L11 | -0.0293202 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0291342 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289017 |
| RPS12 | ribosomal protein S12 | -0.0288298 |
| TXNRD1 | thioredoxin reductase 1 | -0.0286547 |
| RPS16 | ribosomal protein S16 | -0.0283398 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0282427 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0276932 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0275018 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0273545 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0273433 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0272238 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0271209 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0271064 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0270771 |
| RPL31 | ribosomal protein L31 | -0.0270002 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0268459 |
| STC1 | stanniocalcin 1 | -0.0267572 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0265367 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0265044 |
| FTL | ferritin, light polypeptide | -0.0264723 |
| RPL9 | ribosomal protein L9 | -0.0264487 |
| VRK2 | vaccinia related kinase 2 | -0.0263086 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0260324 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0260026 |
| CCNI | cyclin I | -0.0259879 |
| BPTF | bromodomain PHD finger transcription factor | -0.0259109 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.025709 |
| RPL19 | ribosomal protein L19 | -0.0256537 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0256439 |
| PHF20 | PHD finger protein 20 | -0.0253752 |
| FAM20C | family with sequence similarity 20, member C | -0.0253615 |
| LRRC49 | leucine rich repeat containing 49 | -0.0251924 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0251207 |
| PARD3 | par-3 family cell polarity regulator | -0.0250631 |
| DYM | dymeclin | -0.0247196 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0245383 |
