| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.125122 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.11881 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.110411 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.10351 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0978249 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0925419 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0915622 |
| ACTG1 | actin gamma 1 | 0.0835301 |
| AHNAK | AHNAK nucleoprotein | 0.0816796 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0809842 |
| RPL4 | ribosomal protein L4 | 0.076306 |
| ENO1 | enolase 1, (alpha) | 0.0748963 |
| MT2A | metallothionein 2A | 0.0744083 |
| MCL1 | myeloid cell leukemia 1 | 0.0666276 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0618824 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0611093 |
| LDHA | lactate dehydrogenase A | 0.0591767 |
| YBX1 | Y box binding protein 1 | 0.0571157 |
| RPL23 | ribosomal protein L23 | 0.0547301 |
| RPL3 | ribosomal protein L3 | 0.0530858 |
| APP | amyloid beta (A4) precursor protein | 0.0489903 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0458036 |
| CALR | calreticulin | 0.0449246 |
| NNMT | nicotinamide N-methyltransferase | 0.0412455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0410511 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0402442 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0393837 |
| PCBP2 | poly(rC) binding protein 2 | 0.0390609 |
| POTEF | POTE ankyrin domain family, member F | 0.0385525 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0378079 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0372213 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0366292 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0350759 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0349935 |
| PTMA | prothymosin, alpha | 0.034047 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0336667 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0332325 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.033167 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0323641 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0317665 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.031021 |
| RPS3 | ribosomal protein S3 | 0.0307214 |
| WWOX | WW domain containing oxidoreductase | 0.0299573 |
| TPM3 | tropomyosin 3 | 0.0292085 |
| THBS1 | thrombospondin 1 | 0.0288131 |
| FGA | fibrinogen alpha chain | 0.0267702 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0255472 |
| TCIM | transcriptional and immune response regulator | 0.0253807 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0249166 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0242001 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0240302 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0235052 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0231314 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0228019 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0225732 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0224696 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0224254 |
| ANXA1 | annexin A1 | 0.0219426 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0217921 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0213183 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.021243 |
| ATF4 | activating transcription factor 4 | 0.021042 |
| SPAG5 | sperm associated antigen 5 | 0.0209972 |
| ADAR | adenosine deaminase, RNA-specific | 0.0206659 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.02054 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0205142 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0204217 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0201984 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0201042 |
| EFNA5 | ephrin-A5 | 0.0199587 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0198179 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0197215 |
| FAT1 | FAT atypical cadherin 1 | 0.0195193 |
| RRM2 | ribonucleotide reductase M2 | 0.0193749 |
| FGG | fibrinogen gamma chain | 0.0193444 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0189723 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0186719 |
| SET | SET nuclear proto-oncogene | 0.0186503 |
| RACK1 | receptor for activated C kinase 1 | 0.0185263 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0185181 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0183023 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0176699 |
| HYOU1 | hypoxia up-regulated 1 | 0.0176264 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0175312 |
| CALU | calumenin | 0.0173205 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0171085 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0170354 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0165544 |
| FBL | fibrillarin | 0.0164071 |
| TPR | translocated promoter region, nuclear basket protein | 0.0163397 |
| CENPF | centromere protein F, 350/400kDa | 0.0162853 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0162628 |
| MKI67 | marker of proliferation Ki-67 | 0.0162281 |
| DCTN1 | dynactin 1 | 0.0159801 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.015896 |
| ANGPTL4 | angiopoietin-like 4 | 0.0158203 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0157466 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.0157187 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0156246 |
| AK2 | adenylate kinase 2 | 0.015194 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.260529 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.142561 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.133254 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.123098 |
| IGF2 | insulin-like growth factor 2 | -0.121216 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0997726 |
| IER3 | immediate early response 3 | -0.0917796 |
| DENND4A | DENN/MADD domain containing 4A | -0.0734887 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0675998 |
| RTN4 | reticulon 4 | -0.0673833 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0663978 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0661241 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0653318 |
| CMIP | c-Maf inducing protein | -0.0594764 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0587711 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.058215 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0567576 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0562456 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0556124 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0544579 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0502442 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0497183 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0488366 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0458651 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0450633 |
| SPAG9 | sperm associated antigen 9 | -0.0446073 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0445784 |
| TXNRD1 | thioredoxin reductase 1 | -0.0444783 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0435078 |
| ERBIN | erbb2 interacting protein | -0.0433117 |
| ZNF207 | zinc finger protein 207 | -0.0426974 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0416355 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0409843 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0404383 |
| PTK2 | protein tyrosine kinase 2 | -0.0396022 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0389152 |
| RPS6 | ribosomal protein S6 | -0.0385222 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0383701 |
| NOP58 | NOP58 ribonucleoprotein | -0.0382236 |
| VIM | vimentin | -0.037433 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0373475 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0368068 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0367263 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0362971 |
| SETD5 | SET domain containing 5 | -0.0360399 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0359228 |
| USP34 | ubiquitin specific peptidase 34 | -0.0356267 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0350597 |
| STC1 | stanniocalcin 1 | -0.0347045 |
| GOLT1B | golgi transport 1B | -0.0340424 |
| HMGA1 | high mobility group AT-hook 1 | -0.0334992 |
| EGFR | epidermal growth factor receptor | -0.0327229 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0325173 |
| FMNL2 | formin-like 2 | -0.0324321 |
| S100A6 | S100 calcium binding protein A6 | -0.0320827 |
| RPS21 | ribosomal protein S21 | -0.0320076 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | -0.031751 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0312463 |
| UPP1 | uridine phosphorylase 1 | -0.030707 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0304644 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0303879 |
| NAV3 | neuron navigator 3 | -0.0302181 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0296273 |
| SVIL | supervillin | -0.0291243 |
| WTAP | Wilms tumor 1 associated protein | -0.0289458 |
| JMJD1C | jumonji domain containing 1C | -0.0282679 |
| SMAD2 | SMAD family member 2 | -0.0282358 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0280839 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0279166 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0278966 |
| CDCP1 | CUB domain containing protein 1 | -0.0278239 |
| PFN1 | profilin 1 | -0.027786 |
| SLMAP | sarcolemma associated protein | -0.0277211 |
| S100A10 | S100 calcium binding protein A10 | -0.0273871 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0273636 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0271717 |
| KYNU | kynureninase | -0.0270398 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0267894 |
| RPS25 | ribosomal protein S25 | -0.0267084 |
| RBM39 | RNA binding motif protein 39 | -0.0263141 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0262922 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0261886 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.025965 |
| UBC | ubiquitin C | -0.0259601 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0254603 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0253822 |
| WASF2 | WAS protein family, member 2 | -0.0253141 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.025221 |
| PYGL | phosphorylase, glycogen, liver | -0.0250914 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0249571 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0248508 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.024751 |
| TFG | TRK-fused gene | -0.0247246 |
| ZNF292 | zinc finger protein 292 | -0.0243768 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0242812 |
| NDRG1 | N-myc downstream regulated 1 | -0.0242757 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0242117 |
| HDAC9 | histone deacetylase 9 | -0.0241492 |
| FAM107B | family with sequence similarity 107, member B | -0.0240147 |
| RASAL2 | RAS protein activator like 2 | -0.0239126 |
