| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.237741 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.1852 |
| NDRG1 | N-myc downstream regulated 1 | 0.178457 |
| FNDC3B | fibronectin type III domain containing 3B | 0.153991 |
| ACTG1 | actin gamma 1 | 0.153831 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.114756 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0974679 |
| KYNU | kynureninase | 0.0972045 |
| ASPH | aspartate beta-hydroxylase | 0.0970743 |
| PRKCA | protein kinase C, alpha | 0.089268 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0848273 |
| FN1 | fibronectin 1 | 0.0830866 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0828679 |
| FLNB | filamin B, beta | 0.0818906 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0799985 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0782457 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0759796 |
| GPC6 | glypican 6 | 0.0759565 |
| LAMB3 | laminin, beta 3 | 0.075261 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0736261 |
| AOPEP | aminopeptidase O (putative) | 0.0728634 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0709231 |
| VMP1 | vacuole membrane protein 1 | 0.0694756 |
| VIM | vimentin | 0.0686579 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0675305 |
| SBF2 | SET binding factor 2 | 0.0671172 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.066948 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0656461 |
| STC1 | stanniocalcin 1 | 0.0651869 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0645623 |
| PARD3 | par-3 family cell polarity regulator | 0.0636517 |
| OXR1 | oxidation resistance 1 | 0.063439 |
| FAM13A | family with sequence similarity 13, member A | 0.0613841 |
| TPM4 | tropomyosin 4 | 0.0608243 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0604761 |
| MYOF | myoferlin | 0.060355 |
| ANXA2 | annexin A2 | 0.0584634 |
| IRS2 | insulin receptor substrate 2 | 0.0576826 |
| ANXA1 | annexin A1 | 0.0576138 |
| AHNAK | AHNAK nucleoprotein | 0.0575059 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.057401 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0560977 |
| HMGA2 | high mobility group AT-hook 2 | 0.0554188 |
| SETD5 | SET domain containing 5 | 0.0551468 |
| PDE10A | phosphodiesterase 10A | 0.0520071 |
| HELZ | helicase with zinc finger | 0.0517244 |
| RYBP | RING1 and YY1 binding protein | 0.0512852 |
| FAT1 | FAT atypical cadherin 1 | 0.0510462 |
| DSPP | dentin sialophosphoprotein | 0.0479939 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0475554 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0473638 |
| MCL1 | myeloid cell leukemia 1 | 0.0471111 |
| SEPTIN9 | septin 9 | 0.0461912 |
| NF1 | neurofibromin 1 | 0.0458202 |
| SMAD3 | SMAD family member 3 | 0.0446027 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0445136 |
| OGA | O-GlcNAcase | 0.0436056 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.043261 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.040455 |
| LAMC2 | laminin, gamma 2 | 0.0397638 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0393441 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0389621 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0385842 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0383136 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0382556 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0378418 |
| MEF2A | myocyte enhancer factor 2A | 0.0373722 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0360817 |
| TPR | translocated promoter region, nuclear basket protein | 0.0358991 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0345 |
| B2M | beta-2-microglobulin | 0.0338073 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0311745 |
| EFNA5 | ephrin-A5 | 0.0297036 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0296326 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0289533 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0289003 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0288648 |
| USP3 | ubiquitin specific peptidase 3 | 0.0283265 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0281477 |
| NAV2 | neuron navigator 2 | 0.0280856 |
| RORA | RAR-related orphan receptor A | 0.0266281 |
| PRRC2C | proline-rich coiled-coil 2C | 0.025634 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0241299 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0237165 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0227597 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0225782 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0224665 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0221842 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0219199 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0211714 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0204493 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0198969 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0198896 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0196405 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0191363 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0182374 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.018112 |
| SDC4 | syndecan 4 | 0.0176435 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0176427 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0174832 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | -0.172068 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.11633 |
| AGO3 | argonaute RISC catalytic component 3 | -0.10297 |
| SRPK2 | SRSF protein kinase 2 | -0.0985313 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0963913 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0963686 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0963148 |
| PTK2 | protein tyrosine kinase 2 | -0.0955057 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0936273 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0860485 |
| RANBP2 | RAN binding protein 2 | -0.0842694 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0820856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0813162 |
| EGFR | epidermal growth factor receptor | -0.0792843 |
| INSIG1 | insulin induced gene 1 | -0.0779133 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0751041 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0741267 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0723039 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0720477 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0719526 |
| USP33 | ubiquitin specific peptidase 33 | -0.0718935 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0706039 |
| LMO7 | LIM domain 7 | -0.0697487 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0674755 |
| AK1 | adenylate kinase 1 | -0.0674664 |
| RPS6 | ribosomal protein S6 | -0.064688 |
| RLF | rearranged L-myc fusion | -0.0646309 |
| RPL8 | ribosomal protein L8 | -0.063665 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0624155 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0620138 |
| MAP4 | microtubule-associated protein 4 | -0.0616394 |
| SCFD1 | sec1 family domain containing 1 | -0.0591132 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0589538 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.058551 |
| RPS4X | ribosomal protein S4, X-linked | -0.0572434 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0568231 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0552315 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0552129 |
| CD44 | CD44 molecule (Indian blood group) | -0.0551692 |
| RPS12 | ribosomal protein S12 | -0.0550597 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.054749 |
| PTMA | prothymosin, alpha | -0.0536805 |
| PLK2 | polo-like kinase 2 | -0.051148 |
| WAPL | WAPL cohesin release factor | -0.0507545 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0493959 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0490373 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0481974 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0480928 |
| ZNF292 | zinc finger protein 292 | -0.0475291 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.047432 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0472474 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0470507 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0468342 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0465642 |
| DST | dystonin | -0.0463494 |
| MXD1 | MAX dimerization protein 1 | -0.0463458 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0455346 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.04511 |
| CALR | calreticulin | -0.044326 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0432425 |
| RPLP1 | ribosomal protein, large, P1 | -0.0428693 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0419381 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0416335 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0409038 |
| RUNX1 | runt-related transcription factor 1 | -0.04086 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0403135 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0395804 |
| OSMR | oncostatin M receptor | -0.0394277 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0393623 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0390637 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.038965 |
| DIAPH2 | diaphanous-related formin 2 | -0.0374278 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0366009 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0359622 |
| RND3 | Rho family GTPase 3 | -0.0359142 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0348973 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0345846 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0344213 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0343198 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0329549 |
| TMEM165 | transmembrane protein 165 | -0.0324057 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0320404 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0320065 |
| RNF145 | ring finger protein 145 | -0.0315903 |
| CDK19 | cyclin-dependent kinase 19 | -0.0313488 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0307414 |
| VCL | vinculin | -0.0300506 |
| SEPTIN7 | septin 7 | -0.0293924 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0276037 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.026863 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.026495 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0263486 |
| TXNRD1 | thioredoxin reductase 1 | -0.0256963 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0255027 |
| KIF5B | kinesin family member 5B | -0.0247132 |
| CCNL1 | cyclin L1 | -0.0246488 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0246162 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0245641 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0241041 |
| SPAG9 | sperm associated antigen 9 | -0.0239519 |
