| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.172771 |
| EFNA5 | ephrin-A5 | 0.127668 |
| COL5A2 | collagen, type V, alpha 2 | 0.117255 |
| ASPH | aspartate beta-hydroxylase | 0.106296 |
| PDE10A | phosphodiesterase 10A | 0.105308 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0948986 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0947272 |
| PM20D1 | peptidase M20 domain containing 1 | 0.092906 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0889088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0804097 |
| GRAMD1B | GRAM domain containing 1B | 0.0782756 |
| GDA | guanine deaminase | 0.0714431 |
| DST | dystonin | 0.0642475 |
| ENO1 | enolase 1, (alpha) | 0.0626405 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0531323 |
| CENPF | centromere protein F, 350/400kDa | 0.0523292 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0520135 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0491541 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0486928 |
| RPL3 | ribosomal protein L3 | 0.0458985 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0449348 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0446483 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0441874 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0412391 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0401727 |
| MCL1 | myeloid cell leukemia 1 | 0.0398159 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0394874 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0394869 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0385467 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0380348 |
| PCBP3 | poly(rC) binding protein 3 | 0.0378193 |
| CTSC | cathepsin C | 0.0370077 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0361774 |
| SMYD3 | SET and MYND domain containing 3 | 0.0353205 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0343012 |
| SET | SET nuclear proto-oncogene | 0.0341186 |
| SFPQ | splicing factor proline/glutamine-rich | 0.034009 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0339418 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0336053 |
| PCBP2 | poly(rC) binding protein 2 | 0.0328472 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0326645 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0326339 |
| RPL4 | ribosomal protein L4 | 0.0321468 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0313537 |
| MYOF | myoferlin | 0.0311893 |
| AHNAK | AHNAK nucleoprotein | 0.0305503 |
| MKI67 | marker of proliferation Ki-67 | 0.029602 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.029012 |
| TPM3 | tropomyosin 3 | 0.0288182 |
| POTEF | POTE ankyrin domain family, member F | 0.0283412 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0272645 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0268525 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0260796 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0255898 |
| LDHA | lactate dehydrogenase A | 0.02551 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0247111 |
| APP | amyloid beta (A4) precursor protein | 0.0234679 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0230821 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0227651 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0223892 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0223343 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.021996 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0217541 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.021483 |
| RTN1 | reticulon 1 | 0.0206026 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0204926 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0203219 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0201206 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.0200735 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0200257 |
| ANXA1 | annexin A1 | 0.019828 |
| NEK7 | NIMA-related kinase 7 | 0.019813 |
| RAD51B | RAD51 paralog B | 0.0194361 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.019179 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0187377 |
| ACTG1 | actin gamma 1 | 0.0186658 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0186001 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0180258 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0177181 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0174404 |
| TPR | translocated promoter region, nuclear basket protein | 0.0174346 |
| CUL4A | cullin 4A | 0.0173739 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.017288 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0171491 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0170079 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.016759 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0167089 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0166648 |
| YBX1 | Y box binding protein 1 | 0.0166592 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0164838 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0164309 |
| FLNA | filamin A, alpha | 0.0161947 |
| GPC6 | glypican 6 | 0.0161245 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0160768 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0160123 |
| PTEN | phosphatase and tensin homolog | 0.0159824 |
| GPRIN3 | GPRIN family member 3 | 0.0159606 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0158412 |
| CALR | calreticulin | 0.0157754 |
| SCARA5 | scavenger receptor class A, member 5 | 0.0156131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.26915 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.197335 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.132567 |
| VIM | vimentin | -0.116882 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0867113 |
| TMSB10 | thymosin beta 10 | -0.0858343 |
| RPS24 | ribosomal protein S24 | -0.0819516 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0794964 |
| RPS6 | ribosomal protein S6 | -0.0771507 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0733608 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0643595 |
| RPL35A | ribosomal protein L35a | -0.0641909 |
| FTL | ferritin, light polypeptide | -0.0599353 |
| RPLP1 | ribosomal protein, large, P1 | -0.0596648 |
| SPAG9 | sperm associated antigen 9 | -0.0586367 |
| RPS23 | ribosomal protein S23 | -0.0584324 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0574631 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0480943 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0476188 |
| S100A10 | S100 calcium binding protein A10 | -0.0475081 |
| RPL31 | ribosomal protein L31 | -0.047286 |
| RPLP0 | ribosomal protein, large, P0 | -0.0470494 |
| STC1 | stanniocalcin 1 | -0.0464971 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0459239 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0456254 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0451335 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0446852 |
| CDH13 | cadherin 13 | -0.044457 |
| RPL36A | ribosomal protein L36a | -0.0442058 |
| HLA-B | major histocompatibility complex, class I, B | -0.0428603 |
| RPL34 | ribosomal protein L34 | -0.0426692 |
| MAP7 | microtubule-associated protein 7 | -0.0402216 |
| HLA-A | major histocompatibility complex, class I, A | -0.0400597 |
| RPS21 | ribosomal protein S21 | -0.0398679 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0397093 |
| RPS19 | ribosomal protein S19 | -0.0396599 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0395286 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0391492 |
| RPL12 | ribosomal protein L12 | -0.0391359 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0389591 |
| RPS25 | ribosomal protein S25 | -0.0386457 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.038301 |
| RPS8 | ribosomal protein S8 | -0.0378294 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0370698 |
| UBC | ubiquitin C | -0.0369208 |
| GNAS | GNAS complex locus | -0.0367199 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0365343 |
| B2M | beta-2-microglobulin | -0.0365236 |
| NDRG1 | N-myc downstream regulated 1 | -0.0363762 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0360586 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0356445 |
| RPL19 | ribosomal protein L19 | -0.0352417 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0346943 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0341384 |
| RPS16 | ribosomal protein S16 | -0.0334208 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0330385 |
| RPL7A | ribosomal protein L7a | -0.0327865 |
| RPS14 | ribosomal protein S14 | -0.0326299 |
| IER3 | immediate early response 3 | -0.0319314 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0315056 |
| RGS2 | regulator of G-protein signaling 2 | -0.0314962 |
| RPL38 | ribosomal protein L38 | -0.0313917 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0312415 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0309305 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0304269 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0303898 |
| CREB5 | cAMP responsive element binding protein 5 | -0.030306 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0302432 |
| WDR45B | WD repeat domain 45B | -0.030206 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0298887 |
| RPLP2 | ribosomal protein, large, P2 | -0.0298038 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0295956 |
| RPS13 | ribosomal protein S13 | -0.0295837 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0295716 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0295292 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0292544 |
| S100A6 | S100 calcium binding protein A6 | -0.029217 |
| ASTN2 | astrotactin 2 | -0.0291626 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0286658 |
| NBEAL1 | neurobeachin-like 1 | -0.0285782 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.028452 |
| RPS29 | ribosomal protein S29 | -0.0277495 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0276816 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0274829 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0273605 |
| RPL9 | ribosomal protein L9 | -0.0270261 |
| CUX1 | cut-like homeobox 1 | -0.0266747 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0263352 |
| FMNL2 | formin-like 2 | -0.0262795 |
| RPS15 | ribosomal protein S15 | -0.0262013 |
| BMERB1 | bMERB domain containing 1 | -0.0261862 |
| RPS11 | ribosomal protein S11 | -0.026043 |
| RPL32 | ribosomal protein L32 | -0.0255849 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0255298 |
| RPL8 | ribosomal protein L8 | -0.0250138 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0248606 |
| RPL26 | ribosomal protein L26 | -0.0247083 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.024609 |
| FN1 | fibronectin 1 | -0.0244278 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0238934 |
