| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.193592 |
| FMN1 | formin 1 | 0.145408 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.125259 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.119747 |
| QKI | QKI, KH domain containing, RNA binding | 0.110531 |
| FNDC3B | fibronectin type III domain containing 3B | 0.103764 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0975522 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0970657 |
| SRPK2 | SRSF protein kinase 2 | 0.0964971 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.095196 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0936165 |
| GPC6 | glypican 6 | 0.0895647 |
| PGK1 | phosphoglycerate kinase 1 | 0.0860155 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0854367 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.083494 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0822055 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0803721 |
| ACTG1 | actin gamma 1 | 0.0790502 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0769143 |
| MCL1 | myeloid cell leukemia 1 | 0.0750473 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0744793 |
| NLGN1 | neuroligin 1 | 0.0733852 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0724521 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0717966 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0703654 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0696484 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0692126 |
| SBF2 | SET binding factor 2 | 0.0677214 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0676508 |
| DST | dystonin | 0.0669212 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.06676 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0636927 |
| SMAD3 | SMAD family member 3 | 0.0623336 |
| CCNY | cyclin Y | 0.0622383 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0598907 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0597212 |
| LDHA | lactate dehydrogenase A | 0.0597123 |
| VMP1 | vacuole membrane protein 1 | 0.0593727 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.058472 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0574559 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0533481 |
| LSAMP | limbic system-associated membrane protein | 0.0514558 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0507992 |
| TMEM87A | transmembrane protein 87A | 0.0494475 |
| ENO1 | enolase 1, (alpha) | 0.0491001 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0481465 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.047727 |
| COL5A2 | collagen, type V, alpha 2 | 0.0462068 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0447556 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0439027 |
| NKTR | natural killer cell triggering receptor | 0.0434195 |
| SLTM | SAFB-like, transcription modulator | 0.0434115 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0429523 |
| POTEF | POTE ankyrin domain family, member F | 0.0414768 |
| RPL19 | ribosomal protein L19 | 0.0408635 |
| MYOF | myoferlin | 0.040678 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0404794 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0394181 |
| SETD5 | SET domain containing 5 | 0.0388254 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0387212 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0385887 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.036607 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0360553 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0360217 |
| PRELID2 | PRELI domain containing 2 | 0.0340985 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0338907 |
| NDRG1 | N-myc downstream regulated 1 | 0.0334903 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0330122 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0326369 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0325333 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0321065 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0317403 |
| FN1 | fibronectin 1 | 0.0291704 |
| RUNX1 | runt-related transcription factor 1 | 0.0288922 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0286264 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0286262 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0281874 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0277705 |
| MATR3 | matrin 3 | 0.0273621 |
| TPD52 | tumor protein D52 | 0.0269417 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0267707 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0254929 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0249849 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0247255 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0242154 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0241582 |
| GOLGA4 | golgin A4 | 0.0236154 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0231807 |
| GNAS | GNAS complex locus | 0.0228953 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0217432 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0213416 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0200663 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0189943 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0188442 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0185402 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0183578 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0171253 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0160146 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0148483 |
| AHNAK | AHNAK nucleoprotein | 0.0139926 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.260616 |
| VIM | vimentin | -0.212901 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.190474 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.121299 |
| EGFR | epidermal growth factor receptor | -0.110098 |
| RPL34 | ribosomal protein L34 | -0.0951893 |
| FTL | ferritin, light polypeptide | -0.0881814 |
| MT2A | metallothionein 2A | -0.0880054 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0811678 |
| STC1 | stanniocalcin 1 | -0.0767258 |
| RPL35A | ribosomal protein L35a | -0.0755932 |
| PTMA | prothymosin, alpha | -0.0755696 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0717607 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0659135 |
| TXNRD1 | thioredoxin reductase 1 | -0.0628752 |
| RBM25 | RNA binding motif protein 25 | -0.061197 |
| HDLBP | high density lipoprotein binding protein | -0.061139 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0602841 |
| RPL12 | ribosomal protein L12 | -0.0591595 |
| OGA | O-GlcNAcase | -0.0590045 |
| TMSB10 | thymosin beta 10 | -0.0587992 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0587813 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0582718 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0574203 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0571186 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0541014 |
| MTDH | metadherin | -0.0524144 |
| SP100 | SP100 nuclear antigen | -0.0517637 |
| LAMB3 | laminin, beta 3 | -0.0514279 |
| RPS23 | ribosomal protein S23 | -0.0505089 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0498394 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0493491 |
| IGF2 | insulin-like growth factor 2 | -0.0493101 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0491722 |
| RPS24 | ribosomal protein S24 | -0.0476378 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0474729 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0470801 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0463749 |
| CCNI | cyclin I | -0.0460562 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0458214 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0456574 |
| LMO7 | LIM domain 7 | -0.0448518 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.044449 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0441388 |
| KIF5B | kinesin family member 5B | -0.0432791 |
| ZNF292 | zinc finger protein 292 | -0.0432127 |
| ITGA6 | integrin, alpha 6 | -0.0423737 |
| SPAG9 | sperm associated antigen 9 | -0.0416923 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0411615 |
| FOXJ3 | forkhead box J3 | -0.0409294 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0409007 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0406812 |
| PRKCA | protein kinase C, alpha | -0.0405285 |
| B2M | beta-2-microglobulin | -0.0404271 |
| RTN4 | reticulon 4 | -0.0397108 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0393519 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0381382 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0372948 |
| SEPTIN2 | septin 2 | -0.0370691 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0369428 |
| GLG1 | golgi glycoprotein 1 | -0.0360201 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.03595 |
| STK24 | serine/threonine kinase 24 | -0.0353839 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0351117 |
| RPS27A | ribosomal protein S27a | -0.0345104 |
| RACK1 | receptor for activated C kinase 1 | -0.0339497 |
| IER3 | immediate early response 3 | -0.0337745 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0330922 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0322401 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0296164 |
| RPLP2 | ribosomal protein, large, P2 | -0.029281 |
| RPS3 | ribosomal protein S3 | -0.0280343 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0272007 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0265762 |
| RPL37 | ribosomal protein L37 | -0.0263277 |
| LAMA4 | laminin, alpha 4 | -0.0262069 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.026056 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0256941 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0252514 |
| RPLP1 | ribosomal protein, large, P1 | -0.0249454 |
| TXNIP | thioredoxin interacting protein | -0.0247522 |
| MORF4L2 | mortality factor 4 like 2 | -0.0244045 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.02388 |
| FUS | FUS RNA binding protein | -0.023778 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0237552 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0236946 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0228033 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0224995 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0224107 |
| H3-3B | H3.3 histone B | -0.0223927 |
| CDC73 | cell division cycle 73 | -0.0218503 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0217655 |
| MED13 | mediator complex subunit 13 | -0.0215758 |
| PKM | pyruvate kinase, muscle | -0.0215229 |
| RPL26 | ribosomal protein L26 | -0.0213542 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0205447 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0204998 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0198066 |
| RPS19 | ribosomal protein S19 | -0.0196257 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0193344 |
