| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.165093 |
| COL5A2 | collagen, type V, alpha 2 | 0.125082 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.106248 |
| PEG10 | paternally expressed 10 | 0.0970453 |
| TMSB4X | thymosin beta 4, X-linked | 0.0900253 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0894135 |
| POTEF | POTE ankyrin domain family, member F | 0.086925 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.085839 |
| CENPF | centromere protein F, 350/400kDa | 0.0711933 |
| MKI67 | marker of proliferation Ki-67 | 0.0665403 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0664128 |
| ACTG1 | actin gamma 1 | 0.0637478 |
| YBX1 | Y box binding protein 1 | 0.0598007 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.059341 |
| HDAC9 | histone deacetylase 9 | 0.0577373 |
| TPX2 | TPX2, microtubule-associated | 0.0541614 |
| DST | dystonin | 0.0529995 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0526322 |
| WDR43 | WD repeat domain 43 | 0.0507193 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.047661 |
| THBS1 | thrombospondin 1 | 0.0462319 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0457663 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0456775 |
| PCBP2 | poly(rC) binding protein 2 | 0.0453036 |
| KIF5B | kinesin family member 5B | 0.0445524 |
| FBL | fibrillarin | 0.0442276 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.042882 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0423204 |
| RBM39 | RNA binding motif protein 39 | 0.0422181 |
| MATR3 | matrin 3 | 0.040752 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0407351 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0401609 |
| RPL4 | ribosomal protein L4 | 0.0393028 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0388956 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0384615 |
| RPL3 | ribosomal protein L3 | 0.0382821 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0382165 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0380565 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0378208 |
| TPM3 | tropomyosin 3 | 0.0376065 |
| AHNAK | AHNAK nucleoprotein | 0.0375066 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0370818 |
| RLF | rearranged L-myc fusion | 0.0368971 |
| ZFR | zinc finger RNA binding protein | 0.0361827 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0360488 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0357846 |
| RTN4 | reticulon 4 | 0.0356671 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0349911 |
| ZNF292 | zinc finger protein 292 | 0.034876 |
| FAT1 | FAT atypical cadherin 1 | 0.0348144 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0346993 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0340231 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.034014 |
| PTMA | prothymosin, alpha | 0.0338606 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0333532 |
| NOP58 | NOP58 ribonucleoprotein | 0.0333456 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0332072 |
| PDGFC | platelet derived growth factor C | 0.0326121 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0326022 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0324271 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0322 |
| ANXA1 | annexin A1 | 0.0321294 |
| EZR | ezrin | 0.0320375 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0319998 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0316025 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0313374 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0312328 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0310575 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0308852 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0306431 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0306366 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0306228 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0304951 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0303841 |
| HMGB2 | high mobility group box 2 | 0.0302237 |
| WDR26 | WD repeat domain 26 | 0.0300713 |
| NTM | neurotrimin | 0.0300373 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0299352 |
| SET | SET nuclear proto-oncogene | 0.0298758 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0296424 |
| CCNL1 | cyclin L1 | 0.0290973 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0290535 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.029015 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.0285774 |
| ANXA2 | annexin A2 | 0.0285428 |
| TOP1 | topoisomerase (DNA) I | 0.0285278 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0283832 |
| TXNRD1 | thioredoxin reductase 1 | 0.0283319 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0282926 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0282672 |
| ANLN | anillin, actin binding protein | 0.0282669 |
| RNF145 | ring finger protein 145 | 0.0282245 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0281988 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0281124 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0277673 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0277272 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0276717 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0276012 |
| OGA | O-GlcNAcase | 0.0275716 |
| ECT2 | epithelial cell transforming 2 | 0.0275231 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.169067 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.152699 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.151843 |
| COL11A1 | collagen, type XI, alpha 1 | -0.114149 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.103054 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0979609 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0907581 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0873125 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0802191 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0773193 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0738435 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0721183 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0712811 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0697251 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0696928 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0640888 |
| PCDH9 | protocadherin 9 | -0.0595671 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0583346 |
| B2M | beta-2-microglobulin | -0.0573584 |
| PHIP | pleckstrin homology domain interacting protein | -0.0523717 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0519583 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0517898 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0473678 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0466309 |
| HMCN1 | hemicentin 1 | -0.0461497 |
| SMYD3 | SET and MYND domain containing 3 | -0.0434201 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0432632 |
| RPS6 | ribosomal protein S6 | -0.0428782 |
| COL1A2 | collagen, type I, alpha 2 | -0.0422551 |
| RPS16 | ribosomal protein S16 | -0.0417723 |
| TMSB10 | thymosin beta 10 | -0.0407883 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0406244 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0400668 |
| PCDH7 | protocadherin 7 | -0.0396165 |
| GNAS | GNAS complex locus | -0.0380651 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0380627 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0373966 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0368162 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0364223 |
| RBM20 | RNA binding motif protein 20 | -0.0354034 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0353416 |
| RPL35A | ribosomal protein L35a | -0.034684 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.034585 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0344364 |
| HMGA2 | high mobility group AT-hook 2 | -0.0332756 |
| CUX1 | cut-like homeobox 1 | -0.0331134 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0325489 |
| RCOR1 | REST corepressor 1 | -0.0324506 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0323069 |
| SYT1 | synaptotagmin I | -0.0320883 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0320243 |
| FGF13 | fibroblast growth factor 13 | -0.0319825 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0318545 |
| INTS6 | integrator complex subunit 6 | -0.0314807 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0312711 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.030859 |
| RAD51B | RAD51 paralog B | -0.0307113 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0306979 |
| GPC3 | glypican 3 | -0.0306682 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0303294 |
| ATXN2 | ataxin 2 | -0.0298412 |
| BPTF | bromodomain PHD finger transcription factor | -0.0296814 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0295802 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0293306 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0291188 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0290471 |
| PRKD1 | protein kinase D1 | -0.0286855 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0286461 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0285907 |
| TRIM2 | tripartite motif containing 2 | -0.0282305 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0282114 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0281472 |
| MED12L | mediator complex subunit 12-like | -0.0279878 |
| ATXN1 | ataxin 1 | -0.0276415 |
| NBEAL1 | neurobeachin-like 1 | -0.0275877 |
| TNRC6B | trinucleotide repeat containing 6B | -0.027455 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0273555 |
| LPIN2 | lipin 2 | -0.0270005 |
| PGK1 | phosphoglycerate kinase 1 | -0.0266426 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0266407 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0260991 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0258693 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0258553 |
| COL3A1 | collagen, type III, alpha 1 | -0.0256118 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0255995 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0250797 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0246601 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0242182 |
| NHSL1 | NHS-like 1 | -0.023887 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.023847 |
| RPL31 | ribosomal protein L31 | -0.0237423 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0234498 |
| ANK2 | ankyrin 2, neuronal | -0.0234159 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0233868 |
| CNTN6 | contactin 6 | -0.0231801 |
| TFRC | transferrin receptor | -0.0230683 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0229405 |
| GSE1 | Gse1 coiled-coil protein | -0.0227698 |
| PRR16 | proline rich 16 | -0.0225895 |
| MED13L | mediator complex subunit 13-like | -0.0225495 |
