| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.199336 |
| AHNAK | AHNAK nucleoprotein | 0.169812 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.125021 |
| POTEF | POTE ankyrin domain family, member F | 0.113114 |
| ENO1 | enolase 1, (alpha) | 0.112021 |
| PKM | pyruvate kinase, muscle | 0.102283 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0968931 |
| RPL3 | ribosomal protein L3 | 0.0948588 |
| ACTG1 | actin gamma 1 | 0.0845146 |
| TMSB4X | thymosin beta 4, X-linked | 0.0834493 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0799291 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0778122 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0748864 |
| VCL | vinculin | 0.0745088 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0734091 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0676907 |
| EZR | ezrin | 0.0611391 |
| PCBP2 | poly(rC) binding protein 2 | 0.0602564 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0583152 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.058079 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0577045 |
| HDAC9 | histone deacetylase 9 | 0.0534258 |
| TJP1 | tight junction protein 1 | 0.0532789 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0521198 |
| LDHA | lactate dehydrogenase A | 0.0508812 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0503491 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.050292 |
| FOXP1 | forkhead box P1 | 0.0496507 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0487271 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0484325 |
| SET | SET nuclear proto-oncogene | 0.0468285 |
| CALR | calreticulin | 0.0441956 |
| NBEA | neurobeachin | 0.0436868 |
| GLI3 | GLI family zinc finger 3 | 0.0433982 |
| DUSP4 | dual specificity phosphatase 4 | 0.0432916 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0428304 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0421792 |
| MKI67 | marker of proliferation Ki-67 | 0.0413575 |
| RPS3 | ribosomal protein S3 | 0.0409363 |
| MYO5C | myosin VC | 0.0399181 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0388918 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0385814 |
| CENPF | centromere protein F, 350/400kDa | 0.03855 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0381802 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0365681 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0362936 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0358953 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0357102 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.0352139 |
| RPS2 | ribosomal protein S2 | 0.0348908 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0341674 |
| RPL4 | ribosomal protein L4 | 0.0339823 |
| DPYD | dihydropyrimidine dehydrogenase | 0.03396 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.033891 |
| RPS8 | ribosomal protein S8 | 0.032391 |
| PRELID2 | PRELI domain containing 2 | 0.0322759 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0321645 |
| TPM4 | tropomyosin 4 | 0.0306154 |
| ANXA1 | annexin A1 | 0.0305035 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0292656 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0290965 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0290927 |
| GLI2 | GLI family zinc finger 2 | 0.0290422 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0290101 |
| PLXNA1 | plexin A1 | 0.0280618 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0271326 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0265592 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0264352 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0263342 |
| YBX1 | Y box binding protein 1 | 0.0263054 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.025784 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0256699 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0254907 |
| BRD2 | bromodomain containing 2 | 0.0254839 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0253481 |
| RBM26 | RNA binding motif protein 26 | 0.0253016 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0251402 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0249668 |
| GSE1 | Gse1 coiled-coil protein | 0.0248514 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0247523 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.024506 |
| GOLGB1 | golgin B1 | 0.0241963 |
| PRSS23 | protease, serine, 23 | 0.0240348 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0235153 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0232603 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0232425 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0228841 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0228679 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0228139 |
| MACROD2 | MACRO domain containing 2 | 0.0227786 |
| HDGF | hepatoma-derived growth factor | 0.0227286 |
| BMP10 | bone morphogenetic protein 10 | 0.0226183 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0226099 |
| APP | amyloid beta (A4) precursor protein | 0.0224736 |
| FAT1 | FAT atypical cadherin 1 | 0.0224524 |
| NAV2 | neuron navigator 2 | 0.0224284 |
| ITGA6 | integrin, alpha 6 | 0.022387 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0222202 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0220005 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0219623 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.236411 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127464 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0915198 |
| RTN4 | reticulon 4 | -0.0693855 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0649343 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0565721 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0550676 |
| RBM39 | RNA binding motif protein 39 | -0.0503351 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0481032 |
| ZNF292 | zinc finger protein 292 | -0.0472159 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0466228 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0453779 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0448235 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0436348 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0429682 |
| QKI | QKI, KH domain containing, RNA binding | -0.0417021 |
| GOLGA4 | golgin A4 | -0.0415851 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0371767 |
| RLF | rearranged L-myc fusion | -0.0362076 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0336528 |
| CDC73 | cell division cycle 73 | -0.0333217 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0327604 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0318553 |
| NUP58 | nucleoporin 58 | -0.0312875 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0310223 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0303614 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0297709 |
| FBXO11 | F-box protein 11 | -0.0292685 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0292259 |
| NCKAP1 | NCK-associated protein 1 | -0.0290869 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0288014 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0283756 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0283596 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0281682 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.027927 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0274162 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0272689 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0268203 |
| NF1 | neurofibromin 1 | -0.0267125 |
| RPL34 | ribosomal protein L34 | -0.0267068 |
| RHEB | Ras homolog enriched in brain | -0.0266668 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0264678 |
| TMEM41B | transmembrane protein 41B | -0.0258046 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0253632 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0252381 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0243729 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0242285 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0230417 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0229894 |
| COG5 | component of oligomeric golgi complex 5 | -0.0229734 |
| USP3 | ubiquitin specific peptidase 3 | -0.0228905 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0228388 |
| TFG | TRK-fused gene | -0.0223994 |
| RPL35A | ribosomal protein L35a | -0.0223363 |
| WDR45B | WD repeat domain 45B | -0.022255 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0221756 |
| TMEM39A | transmembrane protein 39A | -0.0219857 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0219221 |
| LIMD1 | LIM domains containing 1 | -0.0219208 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0214749 |
| AHI1 | Abelson helper integration site 1 | -0.0210472 |
| CCNL1 | cyclin L1 | -0.0208615 |
| RPS11 | ribosomal protein S11 | -0.0207073 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0206458 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0205154 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0204369 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0204168 |
| RPS24 | ribosomal protein S24 | -0.0200849 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0199925 |
| KIF13A | kinesin family member 13A | -0.0197892 |
| TCF12 | transcription factor 12 | -0.0197291 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0196375 |
| HBP1 | HMG-box transcription factor 1 | -0.01959 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0192194 |
| TLK1 | tousled-like kinase 1 | -0.0191205 |
| FOXJ3 | forkhead box J3 | -0.0190965 |
| NBAS | neuroblastoma amplified sequence | -0.0190603 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0189678 |
| TMEM123 | transmembrane protein 123 | -0.0189139 |
| RPS25 | ribosomal protein S25 | -0.0187557 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0187244 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0187195 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0186615 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0185172 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | -0.0183078 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0180728 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0179793 |
| YBX3 | Y box binding protein 3 | -0.0179401 |
| RASA2 | RAS p21 protein activator 2 | -0.0178087 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0176697 |
| MRTFA | myocardin related transcription factor A | -0.0175417 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0174827 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0173681 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0172415 |
| SPPL3 | signal peptide peptidase like 3 | -0.0171871 |
| PHF21A | PHD finger protein 21A | -0.0171693 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0171676 |
| SETD5 | SET domain containing 5 | -0.0171054 |
| TOP1 | topoisomerase (DNA) I | -0.0170475 |
| SESN2 | sestrin 2 | -0.0169966 |
