| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mifepristone perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mifepristone_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLIN2 | perilipin 2 | 0.509736 |
| FN1 | fibronectin 1 | 0.142925 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.122163 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0907468 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.089438 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0776314 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0772379 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0647437 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0570296 |
| LDHA | lactate dehydrogenase A | 0.0555869 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0525757 |
| ENO1 | enolase 1, (alpha) | 0.050788 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0472463 |
| MKI67 | marker of proliferation Ki-67 | 0.045326 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0432034 |
| CENPF | centromere protein F, 350/400kDa | 0.0428682 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.042803 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0413342 |
| YBX1 | Y box binding protein 1 | 0.0376983 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0355785 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0348215 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0345071 |
| VCAN | versican | 0.0338821 |
| B2M | beta-2-microglobulin | 0.0332179 |
| MT2A | metallothionein 2A | 0.0324641 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0322975 |
| RPS12 | ribosomal protein S12 | 0.0319496 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0307799 |
| RPL3 | ribosomal protein L3 | 0.0285977 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0285379 |
| MSN | moesin | 0.0280408 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0278528 |
| POTEF | POTE ankyrin domain family, member F | 0.0275471 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0268683 |
| SYAP1 | synapse associated protein 1 | 0.0265339 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.026117 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0259455 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0258759 |
| CCNL1 | cyclin L1 | 0.0254294 |
| PTMA | prothymosin, alpha | 0.0251509 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0251388 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0249906 |
| ANGPTL4 | angiopoietin-like 4 | 0.0240377 |
| RPS3 | ribosomal protein S3 | 0.0237133 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0236157 |
| C3 | complement component 3 | 0.0234555 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0234078 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0232786 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0229658 |
| RPL4 | ribosomal protein L4 | 0.0219788 |
| TPM3 | tropomyosin 3 | 0.02186 |
| THBS1 | thrombospondin 1 | 0.0218477 |
| PCBP2 | poly(rC) binding protein 2 | 0.0218061 |
| ANXA1 | annexin A1 | 0.0216948 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0213088 |
| RPS2 | ribosomal protein S2 | 0.0212618 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0202475 |
| SDC4 | syndecan 4 | 0.020235 |
| TPM4 | tropomyosin 4 | 0.020118 |
| ANLN | anillin, actin binding protein | 0.0197846 |
| TXNIP | thioredoxin interacting protein | 0.0197422 |
| ADAR | adenosine deaminase, RNA-specific | 0.0194503 |
| SET | SET nuclear proto-oncogene | 0.0191058 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0187913 |
| OPTN | optineurin | 0.0186821 |
| AHNAK | AHNAK nucleoprotein | 0.0182427 |
| FLNB | filamin B, beta | 0.0181821 |
| ACTG1 | actin gamma 1 | 0.0178006 |
| SNX3 | sorting nexin 3 | 0.017721 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0177028 |
| DSTN | destrin (actin depolymerizing factor) | 0.017685 |
| ANXA5 | annexin A5 | 0.0176245 |
| RPS4X | ribosomal protein S4, X-linked | 0.0174928 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0174536 |
| EZR | ezrin | 0.0171984 |
| RPL37A | ribosomal protein L37a | 0.0171625 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0170321 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0168867 |
| SFTPA2 | surfactant protein A2 | 0.0168619 |
| RPL7 | ribosomal protein L7 | 0.0167259 |
| FAM13A | family with sequence similarity 13, member A | 0.0166478 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0165658 |
| F2R | coagulation factor II (thrombin) receptor | 0.0165512 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0164359 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0163955 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0163526 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0160202 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0160026 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0159018 |
| MX1 | MX dynamin-like GTPase 1 | 0.0157938 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0157619 |
| CALD1 | caldesmon 1 | 0.0157533 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.015729 |
| RTN4 | reticulon 4 | 0.0156995 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0156158 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0156017 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0154894 |
| ITGAV | integrin, alpha V | 0.0150461 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0149647 |
| COL1A2 | collagen, type I, alpha 2 | 0.0148592 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.207039 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.13887 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.137474 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.136157 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.11569 |
| IER3 | immediate early response 3 | -0.110762 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104548 |
| GLIS3 | GLIS family zinc finger 3 | -0.0989118 |
| CDH13 | cadherin 13 | -0.0926275 |
| HMGA2 | high mobility group AT-hook 2 | -0.0826577 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0786684 |
| PDE10A | phosphodiesterase 10A | -0.0690977 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0690707 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0682471 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0680783 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0659684 |
| VIM | vimentin | -0.062879 |
| INTS6 | integrator complex subunit 6 | -0.062215 |
| CADM1 | cell adhesion molecule 1 | -0.0617336 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0606354 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0569855 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0558742 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0553496 |
| CD44 | CD44 molecule (Indian blood group) | -0.0551839 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.054972 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0547872 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0521555 |
| HDAC9 | histone deacetylase 9 | -0.0514618 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0508672 |
| SMYD3 | SET and MYND domain containing 3 | -0.0508027 |
| DST | dystonin | -0.0463443 |
| EGFR | epidermal growth factor receptor | -0.0463227 |
| EXT1 | exostosin glycosyltransferase 1 | -0.04517 |
| UBC | ubiquitin C | -0.0436551 |
| FNIP1 | folliculin interacting protein 1 | -0.0435114 |
| NDRG1 | N-myc downstream regulated 1 | -0.0432277 |
| RAB7A | RAB7A, member RAS oncogene family | -0.042232 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.042173 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0419409 |
| DIAPH2 | diaphanous-related formin 2 | -0.0418987 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0418936 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0418196 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.041115 |
| KYNU | kynureninase | -0.0409889 |
| HLA-B | major histocompatibility complex, class I, B | -0.0397492 |
| NABP1 | nucleic acid binding protein 1 | -0.0392287 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0391344 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0391069 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0384932 |
| COL5A1 | collagen, type V, alpha 1 | -0.0383258 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0378588 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0378106 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0375392 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0374749 |
| RPS24 | ribosomal protein S24 | -0.0373152 |
| TMEM132D | transmembrane protein 132D | -0.0369413 |
| ATXN1 | ataxin 1 | -0.036136 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0361268 |
| ASPH | aspartate beta-hydroxylase | -0.0352821 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0352582 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0342309 |
| NCKAP5 | NCK-associated protein 5 | -0.0341407 |
| SMAD3 | SMAD family member 3 | -0.033752 |
| TNS3 | tensin 3 | -0.0332311 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0325674 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0323093 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0321597 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0321218 |
| RAI14 | retinoic acid induced 14 | -0.0320579 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0319256 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0318737 |
| TMSB10 | thymosin beta 10 | -0.0315808 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0305476 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.029677 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0296437 |
| QKI | QKI, KH domain containing, RNA binding | -0.0294966 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.029298 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0291061 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.028903 |
| MLPH | melanophilin | -0.02886 |
| PRELID2 | PRELI domain containing 2 | -0.0287705 |
| ERBIN | erbb2 interacting protein | -0.0285759 |
| MORF4L2 | mortality factor 4 like 2 | -0.0284393 |
| HLA-E | major histocompatibility complex, class I, E | -0.0281316 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.027957 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0279397 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0277653 |
| BNC2 | basonuclin 2 | -0.0276493 |
| FOXO3 | forkhead box O3 | -0.0274546 |
| NAV2 | neuron navigator 2 | -0.0272772 |
| CANX | calnexin | -0.0270015 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0268934 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0266326 |
| COL1A1 | collagen, type I, alpha 1 | -0.0264831 |
| RUNX1 | runt-related transcription factor 1 | -0.0263625 |
| RPS27A | ribosomal protein S27a | -0.0261875 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0260868 |
| PRKCA | protein kinase C, alpha | -0.0259703 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0259489 |
| MED13 | mediator complex subunit 13 | -0.0258564 |
