Migraine Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing. (Human Disease Ontology, DOID_6364)
External Link https://www.disgenet.org/browser/0/1/0/C1735856
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Genes

92 genes associated with the disease Migraine in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ADORA2A adenosine A2a receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
APOE apolipoprotein E
ASIC1 acid sensing (proton gated) ion channel 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BDNF brain-derived neurotrophic factor
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CALCA calcitonin-related polypeptide alpha
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CAT catalase
CRP C-reactive protein, pentraxin-related
CSAD cysteine sulfinic acid decarboxylase
CSNK1D casein kinase 1, delta
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DPEP1 dipeptidase 1 (renal)
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F5 coagulation factor V (proaccelerin, labile factor)
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FSHR follicle stimulating hormone receptor
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GRIA1 glutamate receptor, ionotropic, AMPA 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IGHMBP2 immunoglobulin mu binding protein 2
IL1B interleukin 1, beta
INSR insulin receptor
KCNK18 potassium channel, two pore domain subfamily K, member 18
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
LDLR low density lipoprotein receptor
LEP leptin
LRP1 low density lipoprotein receptor-related protein 1
LTA lymphotoxin alpha
MAOA monoamine oxidase A
MEF2D myocyte enhancer factor 2D
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NELFE negative elongation factor complex member E
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
OPRM1 opioid receptor, mu 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PRDM16 PR domain containing 16
PRDX1 peroxiredoxin 1
PRRT2 proline-rich transmembrane protein 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SESN2 sestrin 2
SLC25A42 solute carrier family 25, member 42
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPTAN1 spectrin, alpha, non-erythrocytic 1
TAC1 tachykinin, precursor 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNF tumor necrosis factor
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSPAN2 tetraspanin 2
TSPAN33 tetraspanin 33
VSTM4 V-set and transmembrane domain containing 4
VWF von Willebrand factor
WDHD1 WD repeat and HMG-box DNA binding protein 1