Minocycline Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5. (Chemical Entities of Biological Interest Ontology, CHEBI_50694)
External Link http://ctdbase.org/detail.go?type=chem&acc=D008911
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Genes

61 genes/proteins interacting with the chemical Minocycline from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
APP amyloid beta (A4) precursor protein
ATF3 activating transcription factor 3
ATF6 activating transcription factor 6
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BID BH3 interacting domain death agonist
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP12 caspase 12 (gene/pseudogene)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYCS cytochrome c, somatic
DDIT3 DNA-damage-inducible transcript 3
DIABLO diablo, IAP-binding mitochondrial protein
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ERN1 endoplasmic reticulum to nucleus signaling 1
FMR1 fragile X mental retardation 1
GJC2 gap junction protein, gamma 2, 47kDa
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IL1B interleukin 1, beta
IL6 interleukin 6
IL6R interleukin 6 receptor
INA internexin neuronal intermediate filament protein, alpha
JUN jun proto-oncogene
MAPK8 mitogen-activated protein kinase 8
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
NOS2 nitric oxide synthase 2, inducible
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARK2 parkin RBR E3 ubiquitin protein ligase
PRTN3 proteinase 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNAP25 synaptosomal-associated protein, 25kDa
STMN1 stathmin 1
TGFB2 transforming growth factor, beta 2
TNF tumor necrosis factor
TP53 tumor protein p53
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase