| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.193085 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.134543 |
| CD44 | CD44 molecule (Indian blood group) | 0.100869 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0912746 |
| PLAT | plasminogen activator, tissue | 0.0799719 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.076908 |
| DST | dystonin | 0.0729013 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0675674 |
| APP | amyloid beta (A4) precursor protein | 0.0626686 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0621978 |
| PODXL | podocalyxin-like | 0.0606865 |
| NAV1 | neuron navigator 1 | 0.0585974 |
| AHNAK | AHNAK nucleoprotein | 0.0581214 |
| PLEC | plectin | 0.0580247 |
| RNF213 | ring finger protein 213 | 0.0575831 |
| FLNB | filamin B, beta | 0.0573631 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0531439 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0526023 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0521745 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0520336 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0506054 |
| MX2 | MX dynamin-like GTPase 2 | 0.0485362 |
| FSTL1 | follistatin-like 1 | 0.0483031 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0476084 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0459158 |
| SEPTIN9 | septin 9 | 0.0448369 |
| FBN1 | fibrillin 1 | 0.0433665 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.04224 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0393809 |
| MSN | moesin | 0.0389322 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0383456 |
| GLIS3 | GLIS family zinc finger 3 | 0.0377608 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0375662 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0375268 |
| RIGI | RNA sensor RIG-I | 0.0373767 |
| COL3A1 | collagen, type III, alpha 1 | 0.0373032 |
| SFTPA2 | surfactant protein A2 | 0.0368818 |
| PRELID2 | PRELI domain containing 2 | 0.0368021 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0355282 |
| SMAD3 | SMAD family member 3 | 0.0350284 |
| TPM3 | tropomyosin 3 | 0.0337361 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0332334 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0330117 |
| ADAR | adenosine deaminase, RNA-specific | 0.0328166 |
| IL6ST | interleukin 6 signal transducer | 0.0327784 |
| PRSS23 | protease, serine, 23 | 0.0323797 |
| HDAC9 | histone deacetylase 9 | 0.031976 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0319515 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0318374 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0316578 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0316148 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0312464 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0312361 |
| RUNX1 | runt-related transcription factor 1 | 0.0310378 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0306238 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0304118 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0296288 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0295507 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0295397 |
| PRRC2C | proline-rich coiled-coil 2C | 0.029417 |
| FAM219A | family with sequence similarity 219, member A | 0.0293499 |
| OGA | O-GlcNAcase | 0.0291429 |
| ASPH | aspartate beta-hydroxylase | 0.0287579 |
| MYOF | myoferlin | 0.028597 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0277287 |
| FLNA | filamin A, alpha | 0.0276694 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0274175 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0273179 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0272879 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0271872 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0270982 |
| SVIL | supervillin | 0.0270669 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0269148 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0268315 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0267733 |
| OSMR | oncostatin M receptor | 0.0263876 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0257256 |
| MB21D2 | Mab-21 domain containing 2 | 0.0256731 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0256633 |
| FRMD5 | FERM domain containing 5 | 0.0254557 |
| NONO | non-POU domain containing, octamer-binding | 0.0249775 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0248506 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0248171 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0247992 |
| SMYD3 | SET and MYND domain containing 3 | 0.024565 |
| SDC4 | syndecan 4 | 0.0244984 |
| GPC6 | glypican 6 | 0.024374 |
| ZNF217 | zinc finger protein 217 | 0.024299 |
| H1-4 | H1.4 linker histone, cluster member | 0.0240822 |
| SBF2 | SET binding factor 2 | 0.0238235 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0236897 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0236349 |
| TDRD7 | tudor domain containing 7 | 0.0235867 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0234606 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0233752 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0233175 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0233109 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0231397 |
| RAI14 | retinoic acid induced 14 | 0.0231072 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0229532 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.332461 |
| VIM | vimentin | -0.20813 |
| TMSB10 | thymosin beta 10 | -0.091049 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0834356 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0830913 |
| CSTB | cystatin B (stefin B) | -0.0825733 |
| LOX | lysyl oxidase | -0.0769383 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0761621 |
| S100A6 | S100 calcium binding protein A6 | -0.0715862 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0713623 |
| POTEF | POTE ankyrin domain family, member F | -0.0691213 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0636958 |
| SUCNR1 | succinate receptor 1 | -0.0567152 |
| MYADM | myeloid-associated differentiation marker | -0.0561451 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0516553 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0500936 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0478488 |
| TPM4 | tropomyosin 4 | -0.0463215 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0458019 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0437473 |
| B2M | beta-2-microglobulin | -0.0429946 |
| CCND1 | cyclin D1 | -0.0420599 |
| TAGLN2 | transgelin 2 | -0.0410703 |
| UBC | ubiquitin C | -0.0405389 |
| FTL | ferritin, light polypeptide | -0.0383135 |
| PFN1 | profilin 1 | -0.0380621 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.035425 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0344013 |
| FOSL1 | FOS-like antigen 1 | -0.0335438 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0326852 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0318764 |
| INSIG1 | insulin induced gene 1 | -0.0312081 |
| NDRG1 | N-myc downstream regulated 1 | -0.0300284 |
| FBXO11 | F-box protein 11 | -0.0297624 |
| S100A4 | S100 calcium binding protein A4 | -0.0292324 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0287562 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0287279 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0269326 |
| CENPF | centromere protein F, 350/400kDa | -0.026766 |
| GOLGA4 | golgin A4 | -0.0261289 |
| RPL35A | ribosomal protein L35a | -0.0252722 |
| C12ORF75 | chromosome 12 open reading frame 75 | -0.0250373 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0247373 |
| L1CAM | L1 cell adhesion molecule | -0.0246101 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0245971 |
| RPL28 | ribosomal protein L28 | -0.0243912 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0241051 |
| MSI2 | musashi RNA-binding protein 2 | -0.0239628 |
| BSG | basigin (Ok blood group) | -0.023015 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0228532 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0227363 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0226887 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0226842 |
| EGFR | epidermal growth factor receptor | -0.0224706 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0224104 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0223877 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0218406 |
| ZNF207 | zinc finger protein 207 | -0.0216791 |
| SEC61G | Sec61 gamma subunit | -0.0214248 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0212353 |
| UBXN4 | UBX domain protein 4 | -0.0208151 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0207066 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0206388 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0205139 |
| LMNA | lamin A/C | -0.0200972 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.01997 |
| HLA-A | major histocompatibility complex, class I, A | -0.0197981 |
| CYTH3 | cytohesin 3 | -0.0197043 |
| KRT81 | keratin 81, type II | -0.0195857 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0195751 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -0.0193568 |
| MAP1B | microtubule-associated protein 1B | -0.0189355 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.018869 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0188306 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0187247 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0182772 |
| S100A9 | S100 calcium binding protein A9 | -0.0182748 |
| GDF15 | growth differentiation factor 15 | -0.0181166 |
| SEPTIN7 | septin 7 | -0.0176945 |
| LRRC17 | leucine rich repeat containing 17 | -0.0175127 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0175125 |
| VAT1 | vesicle amine transport 1 | -0.0169026 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0167287 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0167021 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0166944 |
| ACTG1 | actin gamma 1 | -0.0166416 |
| HM13 | histocompatibility (minor) 13 | -0.0166134 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0164018 |
| MTDH | metadherin | -0.0161601 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0160378 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0160058 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.0160043 |
| CD151 | CD151 molecule (Raph blood group) | -0.0159617 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0159085 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0158376 |
| RPL34 | ribosomal protein L34 | -0.0155858 |
| MNT | MAX network transcriptional repressor | -0.0155004 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0152717 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0152523 |
| IL32 | interleukin 32 | -0.0151007 |
