| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.17454 |
| HMGA2 | high mobility group AT-hook 2 | 0.150987 |
| MYL12B | myosin, light chain 12B, regulatory | 0.14335 |
| VIM | vimentin | 0.129325 |
| RAB7A | RAB7A, member RAS oncogene family | 0.113191 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0912593 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0901627 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0825943 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0809549 |
| ACTG1 | actin gamma 1 | 0.0709821 |
| YBX3 | Y box binding protein 3 | 0.0679631 |
| RPL35A | ribosomal protein L35a | 0.0653715 |
| GCG | glucagon | 0.0629529 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0613818 |
| EGR1 | early growth response 1 | 0.0600527 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0585509 |
| TUBA1B | tubulin, alpha 1b | 0.0578339 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0575243 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.055074 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.054102 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0540152 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0536888 |
| YAP1 | Yes-associated protein 1 | 0.0496303 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0486311 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.048192 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0481257 |
| ADIPOR2 | adiponectin receptor 2 | 0.0480963 |
| PCDH7 | protocadherin 7 | 0.0479778 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0454861 |
| RPLP0 | ribosomal protein, large, P0 | 0.0447292 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0442459 |
| INTS6 | integrator complex subunit 6 | 0.0436912 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0433115 |
| EHBP1 | EH domain binding protein 1 | 0.042845 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0427035 |
| RRM2 | ribonucleotide reductase M2 | 0.0419496 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0406058 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0370702 |
| CDK12 | cyclin-dependent kinase 12 | 0.0361179 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0353082 |
| TUBA1C | tubulin, alpha 1c | 0.0351777 |
| DENND5A | DENN/MADD domain containing 5A | 0.0345895 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0345482 |
| CBX3 | chromobox homolog 3 | 0.0342899 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0341289 |
| TMEM41B | transmembrane protein 41B | 0.0339851 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0337745 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0333093 |
| PRDX1 | peroxiredoxin 1 | 0.0323 |
| RPS24 | ribosomal protein S24 | 0.0321846 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0318857 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0315484 |
| NLGN1 | neuroligin 1 | 0.0315447 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0314608 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0313836 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0309306 |
| ASPH | aspartate beta-hydroxylase | 0.030615 |
| MMP12 | matrix metallopeptidase 12 | 0.030396 |
| CALR | calreticulin | 0.0299279 |
| CENPF | centromere protein F, 350/400kDa | 0.0295209 |
| ZNF804A | zinc finger protein 804A | 0.0293016 |
| RPS21 | ribosomal protein S21 | 0.0289078 |
| RPL34 | ribosomal protein L34 | 0.0283926 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0281015 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0279196 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.027774 |
| CANX | calnexin | 0.0276158 |
| JMJD1C | jumonji domain containing 1C | 0.0272991 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.027144 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0270252 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0269701 |
| SETX | senataxin | 0.0268884 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0265083 |
| IPO7 | importin 7 | 0.026413 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.026286 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0261632 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0261369 |
| PFN1 | profilin 1 | 0.0254562 |
| S100A6 | S100 calcium binding protein A6 | 0.0248447 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0247895 |
| RPL23 | ribosomal protein L23 | 0.0244701 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0244295 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0243571 |
| MTAP | methylthioadenosine phosphorylase | 0.0241438 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0240602 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0238585 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0235945 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0234364 |
| FUS | FUS RNA binding protein | 0.0231369 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0227713 |
| EDARADD | EDAR-associated death domain | 0.0227508 |
| CCDC47 | coiled-coil domain containing 47 | 0.0224357 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0224 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0223557 |
| HMGA1 | high mobility group AT-hook 1 | 0.0223395 |
| NABP1 | nucleic acid binding protein 1 | 0.0222738 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0222164 |
| KHSRP | KH-type splicing regulatory protein | 0.0222083 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0218111 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0217798 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS12 | ribosomal protein S12 | -0.0896221 |
| RPL37A | ribosomal protein L37a | -0.0810863 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0791487 |
| RPS29 | ribosomal protein S29 | -0.0523359 |
| RPS3 | ribosomal protein S3 | -0.0413151 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0350766 |
| RPL36 | ribosomal protein L36 | -0.0347465 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0335164 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0326662 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.032581 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0314565 |
| MGAT4C | MGAT4 family, member C | -0.0312292 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0301267 |
| THOC1 | THO complex 1 | -0.0301091 |
| ZNF292 | zinc finger protein 292 | -0.0290994 |
| RPLP2 | ribosomal protein, large, P2 | -0.0287994 |
| RPS27 | ribosomal protein S27 | -0.0287979 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0284718 |
| ECT2 | epithelial cell transforming 2 | -0.0282573 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0280148 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0279227 |
| AREG | amphiregulin | -0.027544 |
| RPS8 | ribosomal protein S8 | -0.027121 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0269827 |
| PCBP2 | poly(rC) binding protein 2 | -0.0267186 |
| RPL13A | ribosomal protein L13a | -0.026509 |
| RPL35 | ribosomal protein L35 | -0.0264559 |
| PRR16 | proline rich 16 | -0.0262534 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0258964 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0253472 |
| RBM39 | RNA binding motif protein 39 | -0.0249205 |
| NEK7 | NIMA-related kinase 7 | -0.0243147 |
| WDR43 | WD repeat domain 43 | -0.0238684 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0233093 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0232135 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0230229 |
| ATP11B | ATPase, class VI, type 11B | -0.0226594 |
| CPOX | coproporphyrinogen oxidase | -0.0225445 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0222711 |
| RPL28 | ribosomal protein L28 | -0.0222111 |
| TNPO1 | transportin 1 | -0.022075 |
| RPS15A | ribosomal protein S15a | -0.0216668 |
| PKM | pyruvate kinase, muscle | -0.02165 |
| RPS23 | ribosomal protein S23 | -0.0216265 |
| YBX1 | Y box binding protein 1 | -0.0216098 |
| DST | dystonin | -0.0214161 |
| OXR1 | oxidation resistance 1 | -0.0211841 |
| RSF1 | remodeling and spacing factor 1 | -0.0209994 |
| SBF2 | SET binding factor 2 | -0.0209856 |
| CDC27 | cell division cycle 27 | -0.0208245 |
| YEATS2 | YEATS domain containing 2 | -0.02063 |
| PNN | pinin, desmosome associated protein | -0.0204594 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0204418 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0203676 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0201986 |
| TPD52 | tumor protein D52 | -0.0200944 |
| COG5 | component of oligomeric golgi complex 5 | -0.0199719 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0196346 |
| SYT1 | synaptotagmin I | -0.0195188 |
| CPNE1 | copine I | -0.0194422 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0192833 |
| ATP11A | ATPase, class VI, type 11A | -0.0192815 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0192745 |
| PREPL | prolyl endopeptidase-like | -0.0192488 |
| RPS17 | ribosomal protein S17 | -0.019183 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0190598 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0189903 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0188773 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0188287 |
| RPS13 | ribosomal protein S13 | -0.0187516 |
| NEMF | nuclear export mediator factor | -0.0186721 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0186708 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0186558 |
| RPS6 | ribosomal protein S6 | -0.0186373 |
| RASA2 | RAS p21 protein activator 2 | -0.0184628 |
| CCDC14 | coiled-coil domain containing 14 | -0.0182192 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0182144 |
| RPL38 | ribosomal protein L38 | -0.0181026 |
| QKI | QKI, KH domain containing, RNA binding | -0.0179699 |
| ENAH | enabled homolog (Drosophila) | -0.0179419 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0177307 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0176627 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0176567 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0176129 |
| TSPAN5 | tetraspanin 5 | -0.0176043 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0175543 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0175406 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0174868 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0173921 |
| EZR | ezrin | -0.0170985 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0168521 |
| GOLGA4 | golgin A4 | -0.0168401 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0167852 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0165497 |
| RPS19 | ribosomal protein S19 | -0.0165369 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0164023 |
| KLHL24 | kelch-like family member 24 | -0.0163633 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0161805 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0161084 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0160951 |
