| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Minodronic acid_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL19 | ribosomal protein L19 | 0.176998 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.111698 |
| ASPH | aspartate beta-hydroxylase | 0.108505 |
| RPS3 | ribosomal protein S3 | 0.100943 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0964806 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0923665 |
| RPL23 | ribosomal protein L23 | 0.0883162 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0801804 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0767468 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0765552 |
| RPL35 | ribosomal protein L35 | 0.0726216 |
| DSPP | dentin sialophosphoprotein | 0.0641689 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0613021 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0585602 |
| MT2A | metallothionein 2A | 0.0569674 |
| SET | SET nuclear proto-oncogene | 0.0554022 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0552705 |
| TMSB4X | thymosin beta 4, X-linked | 0.0543316 |
| LOC112694756 | uncharaterized LOC112694756 | 0.051106 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0506187 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0502328 |
| APP | amyloid beta (A4) precursor protein | 0.0461946 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0459562 |
| AHNAK | AHNAK nucleoprotein | 0.0459075 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0438732 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0438641 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0418858 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0405074 |
| CLTC | clathrin, heavy chain (Hc) | 0.0391741 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.038812 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0384208 |
| TC2N | tandem C2 domains, nuclear | 0.0382996 |
| CCNI | cyclin I | 0.037337 |
| RPL12 | ribosomal protein L12 | 0.0362815 |
| PTMA | prothymosin, alpha | 0.0358216 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0349692 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0345376 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0344454 |
| KIF5B | kinesin family member 5B | 0.0344388 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0344119 |
| RPS8 | ribosomal protein S8 | 0.0344105 |
| SMYD3 | SET and MYND domain containing 3 | 0.0343946 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0342906 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.034243 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0341414 |
| ZNF217 | zinc finger protein 217 | 0.0340964 |
| RPL8 | ribosomal protein L8 | 0.0339918 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0336724 |
| HMGB2 | high mobility group box 2 | 0.0323511 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0321805 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0319282 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0318085 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0317699 |
| AREG | amphiregulin | 0.0317522 |
| RACK1 | receptor for activated C kinase 1 | 0.031439 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0310352 |
| LDHA | lactate dehydrogenase A | 0.0310099 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0308085 |
| RPS19 | ribosomal protein S19 | 0.0308033 |
| PNN | pinin, desmosome associated protein | 0.0307751 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.0306349 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.030577 |
| CANX | calnexin | 0.0302434 |
| EZR | ezrin | 0.0302008 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0295417 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0292459 |
| LRRC59 | leucine rich repeat containing 59 | 0.0291324 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0287113 |
| RPS27 | ribosomal protein S27 | 0.0284481 |
| RPL3 | ribosomal protein L3 | 0.0283814 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0282801 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0281444 |
| ACTG1 | actin gamma 1 | 0.0277426 |
| TPM3 | tropomyosin 3 | 0.0274256 |
| CENPF | centromere protein F, 350/400kDa | 0.0273408 |
| TXNRD1 | thioredoxin reductase 1 | 0.0272435 |
| TPI1 | triosephosphate isomerase 1 | 0.0271985 |
| OSMR | oncostatin M receptor | 0.026749 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0264392 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0262385 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0259737 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0258578 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0254038 |
| UBC | ubiquitin C | 0.0248598 |
| KRT18 | keratin 18, type I | 0.0248234 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0247641 |
| ANLN | anillin, actin binding protein | 0.0245786 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0245314 |
| DST | dystonin | 0.0245158 |
| RPL18 | ribosomal protein L18 | 0.024493 |
| TUBB | tubulin, beta class I | 0.0243305 |
| CTTN | cortactin | 0.0241731 |
| TMSB10 | thymosin beta 10 | 0.0241313 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0241305 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0240964 |
| ITGB6 | integrin, beta 6 | 0.0239935 |
| RPS12 | ribosomal protein S12 | 0.0238745 |
| PLEC | plectin | 0.0235587 |
| RPS15A | ribosomal protein S15a | 0.0234836 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0234568 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0673764 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0622174 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0547336 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.05444 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0519526 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0508407 |
| DTNA | dystrobrevin, alpha | -0.0504592 |
| POTEF | POTE ankyrin domain family, member F | -0.0489153 |
| VMP1 | vacuole membrane protein 1 | -0.0469059 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0468279 |
| MCL1 | myeloid cell leukemia 1 | -0.0455421 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0444949 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0433003 |
| INTS6 | integrator complex subunit 6 | -0.0428171 |
| RPL35A | ribosomal protein L35a | -0.0424188 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0421955 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0389579 |
| RBM47 | RNA binding motif protein 47 | -0.0388138 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0365289 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0359572 |
| NDRG1 | N-myc downstream regulated 1 | -0.0339133 |
| FASN | fatty acid synthase | -0.0335501 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0331325 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0323969 |
| RCOR1 | REST corepressor 1 | -0.0323225 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | -0.0307204 |
| VCL | vinculin | -0.0303619 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0276609 |
| KIF16B | kinesin family member 16B | -0.0273774 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0273375 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0271752 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0270297 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0266787 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0264237 |
| ZNF207 | zinc finger protein 207 | -0.0262924 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.0259548 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0257058 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0254085 |
| ENAH | enabled homolog (Drosophila) | -0.0252791 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0251761 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0249777 |
| TCEA2 | transcription elongation factor A (SII), 2 | -0.0246466 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0242572 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0241629 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0232494 |
| DENND1A | DENN/MADD domain containing 1A | -0.0230184 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0229804 |
| PLSCR2 | phospholipid scramblase 2 | -0.0229087 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0228663 |
| MSI2 | musashi RNA-binding protein 2 | -0.0226815 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0226797 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0226505 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0225131 |
| EGR1 | early growth response 1 | -0.0224596 |
| RTN3 | reticulon 3 | -0.022416 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | -0.0223906 |
| KIAA1217 | KIAA1217 | -0.0221778 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0217177 |
| TMEM41B | transmembrane protein 41B | -0.0216685 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0212827 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0211194 |
| PCBP2 | poly(rC) binding protein 2 | -0.0209174 |
| FADS2 | fatty acid desaturase 2 | -0.0209165 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0207093 |
| UBAP2 | ubiquitin associated protein 2 | -0.0206841 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0204824 |
| MRTFA | myocardin related transcription factor A | -0.0203508 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.020275 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0199601 |
| SHROOM3 | shroom family member 3 | -0.0199397 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0198285 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0197742 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0193877 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0192889 |
| RPS20 | ribosomal protein S20 | -0.0189102 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.0186539 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0185528 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0184435 |
| COBL | cordon-bleu WH2 repeat protein | -0.0183466 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0181212 |
| TAPBP | TAP binding protein (tapasin) | -0.0180036 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0179814 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0176792 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0176544 |
| PLSCR1 | phospholipid scramblase 1 | -0.017652 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0176054 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0175538 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.0175233 |
| THRB | thyroid hormone receptor, beta | -0.0173616 |
| ACTN4 | actinin, alpha 4 | -0.0172998 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0171524 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0170414 |
| ADIPOR2 | adiponectin receptor 2 | -0.016753 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0167524 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0166011 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0165807 |
| RBM25 | RNA binding motif protein 25 | -0.0165615 |
| MED13L | mediator complex subunit 13-like | -0.0163685 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.016247 |
| LASP1NB | LASP1 neighbor | -0.0161752 |
