| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.343728 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.109279 |
| GPC6 | glypican 6 | 0.106393 |
| VIM | vimentin | 0.0809855 |
| FMN1 | formin 1 | 0.0756626 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0750102 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0595687 |
| ASPH | aspartate beta-hydroxylase | 0.0550757 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0542091 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.051968 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0449203 |
| ACTG1 | actin gamma 1 | 0.0444391 |
| SFTPA2 | surfactant protein A2 | 0.0434098 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0412643 |
| VGF | VGF nerve growth factor inducible | 0.0407537 |
| ACTN1 | actinin, alpha 1 | 0.0406663 |
| CUX1 | cut-like homeobox 1 | 0.0377488 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.036653 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0354067 |
| SETBP1 | SET binding protein 1 | 0.0334141 |
| PARVB | parvin, beta | 0.0318136 |
| APP | amyloid beta (A4) precursor protein | 0.0316542 |
| S100A6 | S100 calcium binding protein A6 | 0.0314533 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0313994 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.031387 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.03136 |
| NAV1 | neuron navigator 1 | 0.0312248 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0296556 |
| TNNC1 | troponin C type 1 (slow) | 0.0295312 |
| ENO1 | enolase 1, (alpha) | 0.0290565 |
| PGK1 | phosphoglycerate kinase 1 | 0.0288751 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0288462 |
| FRMD4A | FERM domain containing 4A | 0.0288167 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0285667 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0268439 |
| SEPTIN9 | septin 9 | 0.0268165 |
| NAV2 | neuron navigator 2 | 0.0266339 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0263647 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0262726 |
| LMNA | lamin A/C | 0.0259501 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0254788 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0254349 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0249939 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0247499 |
| AHNAK | AHNAK nucleoprotein | 0.0241004 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0237461 |
| CENPF | centromere protein F, 350/400kDa | 0.023447 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0227693 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0226068 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0226046 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0225219 |
| ZYX | zyxin | 0.022106 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0217276 |
| AFAP1 | actin filament associated protein 1 | 0.0216217 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0214209 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0212596 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0210405 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0209005 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0208492 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0206347 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0206136 |
| A2M | alpha-2-macroglobulin | 0.0205309 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0201569 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0196787 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0195937 |
| OSMR | oncostatin M receptor | 0.0193028 |
| ARFGEF3 | ARFGEF family member 3 | 0.0192733 |
| LAMB1 | laminin, beta 1 | 0.0189362 |
| JMJD1C | jumonji domain containing 1C | 0.0186354 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0185806 |
| ACTN4 | actinin, alpha 4 | 0.0182582 |
| TMEM178B | transmembrane protein 178B | 0.0182044 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0177193 |
| SMYD3 | SET and MYND domain containing 3 | 0.0175224 |
| RASA3 | RAS p21 protein activator 3 | 0.0174844 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0172051 |
| PCDH7 | protocadherin 7 | 0.0171438 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0169833 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0168627 |
| SSH1 | slingshot protein phosphatase 1 | 0.0166035 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0165429 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0163945 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0163766 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0162974 |
| SHROOM4 | shroom family member 4 | 0.016292 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0162193 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0160809 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0159805 |
| CLIC4 | chloride intracellular channel 4 | 0.0158425 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0157565 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0157525 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0156837 |
| MYO1E | myosin IE | 0.0156602 |
| PHF21A | PHD finger protein 21A | 0.0155979 |
| PYGL | phosphorylase, glycogen, liver | 0.0155525 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.0155274 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0154078 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0153641 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0153268 |
| TPM4 | tropomyosin 4 | 0.0152199 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0867615 |
| RPL37A | ribosomal protein L37a | -0.0300201 |
| NBAS | neuroblastoma amplified sequence | -0.0288953 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0285173 |
| TMSB10 | thymosin beta 10 | -0.0270576 |
| RPS12 | ribosomal protein S12 | -0.0252213 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0234136 |
| GOLGA4 | golgin A4 | -0.0232874 |
| COPA | coatomer protein complex, subunit alpha | -0.0227729 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0215498 |
| CDC73 | cell division cycle 73 | -0.0212737 |
| CALR | calreticulin | -0.0201729 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0189599 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0188542 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0180974 |
| PTK2 | protein tyrosine kinase 2 | -0.0175883 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0163301 |
| RNF145 | ring finger protein 145 | -0.0159824 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0159363 |
| RPS3 | ribosomal protein S3 | -0.0157307 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0154569 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0152689 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.015195 |
| CD109 | CD109 molecule | -0.014974 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0147727 |
| FBXO42 | F-box protein 42 | -0.0141982 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0139576 |
| NAV3 | neuron navigator 3 | -0.0139118 |
| NDRG1 | N-myc downstream regulated 1 | -0.0136887 |
| RBM25 | RNA binding motif protein 25 | -0.0131076 |
| TFG | TRK-fused gene | -0.0127719 |
| RPLP2 | ribosomal protein, large, P2 | -0.0126439 |
| SAMTOR | S-adenosylmethionine sensor upstream of mTORC1 | -0.0126269 |
| RUNX1 | runt-related transcription factor 1 | -0.0125152 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0120198 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0119381 |
| TNPO3 | transportin 3 | -0.0118478 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0112064 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0111955 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0111544 |
| RFX7 | regulatory factor X, 7 | -0.0111536 |
| PCBP2 | poly(rC) binding protein 2 | -0.0111063 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.011061 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0109928 |
| LNPK | lunapark, ER junction formation factor | -0.0108798 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0108753 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0108694 |
| CALU | calumenin | -0.0107027 |
| ZNF638 | zinc finger protein 638 | -0.010581 |
| PDE10A | phosphodiesterase 10A | -0.0105235 |
| NEGR1 | neuronal growth regulator 1 | -0.0104293 |
| SEM1 | SEM1 26S proteasome subunit | -0.0104231 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0103266 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0101764 |
| RNF150 | ring finger protein 150 | -0.0101207 |
| CCNL1 | cyclin L1 | -0.0100975 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00975468 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.00954998 |
| RPL30 | ribosomal protein L30 | -0.00954567 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.00946568 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00945298 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00941794 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.00941704 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00920905 |
| CDK8 | cyclin-dependent kinase 8 | -0.00918125 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.00906932 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00890501 |
| RBM26 | RNA binding motif protein 26 | -0.00890447 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.00876633 |
| HYOU1 | hypoxia up-regulated 1 | -0.00871012 |
| RPL26 | ribosomal protein L26 | -0.00859725 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.00856631 |
| WDR43 | WD repeat domain 43 | -0.00855717 |
| ETNK1 | ethanolamine kinase 1 | -0.00849767 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00849536 |
| COG5 | component of oligomeric golgi complex 5 | -0.00840342 |
| MEF2A | myocyte enhancer factor 2A | -0.00829809 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.00820105 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00811512 |
| CTTNBP2 | cortactin binding protein 2 | -0.00809191 |
| TMEM263 | transmembrane protein 263 | -0.00804503 |
| PFN1 | profilin 1 | -0.0080039 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.00798196 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.00795346 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.00793167 |
| SNX13 | sorting nexin 13 | -0.0078992 |
| RPS13 | ribosomal protein S13 | -0.00789909 |
| RTN4 | reticulon 4 | -0.0078156 |
| SCARB1 | scavenger receptor class B, member 1 | -0.00778647 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0077248 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.00769624 |
| EBF1 | early B-cell factor 1 | -0.00763527 |
| TMF1 | TATA element modulatory factor 1 | -0.00762166 |
| UTRN | utrophin | -0.00761032 |
| FAM120A | family with sequence similarity 120A | -0.00757176 |
| RPS29 | ribosomal protein S29 | -0.00755702 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0075111 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00745293 |
| RPL35 | ribosomal protein L35 | -0.00744751 |
| RBM39 | RNA binding motif protein 39 | -0.00744215 |
