| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.183892 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.119768 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.118401 |
| ANXA2 | annexin A2 | 0.0985501 |
| SMAD3 | SMAD family member 3 | 0.0904503 |
| MYO1E | myosin IE | 0.0894613 |
| B2M | beta-2-microglobulin | 0.0866638 |
| VCL | vinculin | 0.0865348 |
| EGR1 | early growth response 1 | 0.0729684 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0685137 |
| INTS6 | integrator complex subunit 6 | 0.0661723 |
| EFNB2 | ephrin-B2 | 0.0642192 |
| HLA-B | major histocompatibility complex, class I, B | 0.0629985 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.062634 |
| LCN2 | lipocalin 2 | 0.0619465 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0595859 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0589302 |
| RNF213 | ring finger protein 213 | 0.0588397 |
| EZR | ezrin | 0.0558621 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0551513 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0534755 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0533374 |
| TJP1 | tight junction protein 1 | 0.0521406 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0514114 |
| ACTN4 | actinin, alpha 4 | 0.0495569 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0491994 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0488357 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.048495 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0480453 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0452091 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0447471 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0442124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.044167 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0435811 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0434735 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0432704 |
| ASPH | aspartate beta-hydroxylase | 0.0406859 |
| SDC4 | syndecan 4 | 0.0397632 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0391553 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0387083 |
| RPL35A | ribosomal protein L35a | 0.0385325 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0375739 |
| STK24 | serine/threonine kinase 24 | 0.0370923 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0369038 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0364134 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0361327 |
| MAP7 | microtubule-associated protein 7 | 0.0347493 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0346145 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0339794 |
| AREG | amphiregulin | 0.0337804 |
| RRBP1 | ribosome binding protein 1 | 0.0333762 |
| TMC5 | transmembrane channel-like 5 | 0.0332344 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0330827 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0323968 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0321173 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0320728 |
| RPL12 | ribosomal protein L12 | 0.031942 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0302112 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0300597 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0298333 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0297631 |
| SPAG9 | sperm associated antigen 9 | 0.0296627 |
| SFTPA2 | surfactant protein A2 | 0.0294294 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0292432 |
| TXNIP | thioredoxin interacting protein | 0.0286853 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.028544 |
| RPS6 | ribosomal protein S6 | 0.0279331 |
| MT2A | metallothionein 2A | 0.0275599 |
| RPL34 | ribosomal protein L34 | 0.0274312 |
| S100A10 | S100 calcium binding protein A10 | 0.0272297 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0271252 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0270828 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0270246 |
| FHL2 | four and a half LIM domains 2 | 0.0269597 |
| RPL23 | ribosomal protein L23 | 0.0269119 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0268199 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0268081 |
| JUN | jun proto-oncogene | 0.0266862 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0266677 |
| PERP | PERP, TP53 apoptosis effector | 0.0265174 |
| SQSTM1 | sequestosome 1 | 0.0264791 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0261536 |
| HLA-C | major histocompatibility complex, class I, C | 0.0261106 |
| MCL1 | myeloid cell leukemia 1 | 0.0258305 |
| SMYD3 | SET and MYND domain containing 3 | 0.0257034 |
| IRS2 | insulin receptor substrate 2 | 0.0250458 |
| TUFT1 | tuftelin 1 | 0.0248509 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0246611 |
| HKDC1 | hexokinase domain containing 1 | 0.0245798 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0243075 |
| RPLP1 | ribosomal protein, large, P1 | 0.0239702 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0239059 |
| SEPTIN9 | septin 9 | 0.0238568 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0237621 |
| MCU | mitochondrial calcium uniporter | 0.0236705 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0234834 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0234524 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233845 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0228797 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0227867 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0439932 |
| NPSR1 | neuropeptide S receptor 1 | -0.042192 |
| LYZ | lysozyme | -0.0414677 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0405155 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0403638 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0393975 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0389248 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.034959 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0334903 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0330296 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0306481 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0301941 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0288511 |
| PTEN | phosphatase and tensin homolog | -0.0254765 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0253441 |
| UBAC2 | UBA domain containing 2 | -0.0244972 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0235216 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0230113 |
| SSH2 | slingshot protein phosphatase 2 | -0.0226129 |
| RBM26 | RNA binding motif protein 26 | -0.0209355 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.020878 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0206568 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0202935 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0201909 |
| SPATA13 | spermatogenesis associated 13 | -0.0200624 |
| STK39 | serine threonine kinase 39 | -0.0196989 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0195467 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0194644 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0193347 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0192834 |
| SYT1 | synaptotagmin I | -0.0188502 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0184803 |
| CCDC146 | coiled-coil domain containing 146 | -0.0183513 |
| MECOM | MDS1 and EVI1 complex locus | -0.0182093 |
| THOC2 | THO complex 2 | -0.0181778 |
| ATP10B | ATPase, class V, type 10B | -0.0179468 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0179302 |
| ZNRF3 | zinc and ring finger 3 | -0.0175443 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0175389 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0170349 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0169803 |
| PTGR1 | prostaglandin reductase 1 | -0.0165656 |
| MEF2A | myocyte enhancer factor 2A | -0.0163667 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0163524 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0162697 |
| GOLGB1 | golgin B1 | -0.0158029 |
| CTSD | cathepsin D | -0.0156986 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0155645 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0154717 |
| PRELID2 | PRELI domain containing 2 | -0.0152746 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0152419 |
| PRKCA | protein kinase C, alpha | -0.0151602 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0151254 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0150731 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0150538 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.014936 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0147809 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0146876 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0144712 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0142626 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0141469 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0141121 |
| DGKH | diacylglycerol kinase, eta | -0.0140763 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.014069 |
| CCNL1 | cyclin L1 | -0.0139141 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0139046 |
| PMP22 | peripheral myelin protein 22 | -0.0137729 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0137248 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0135494 |
| PANK3 | pantothenate kinase 3 | -0.0134248 |
| ALPK1 | alpha-kinase 1 | -0.013418 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0133364 |
| CMIP | c-Maf inducing protein | -0.0132278 |
| GOLGA4 | golgin A4 | -0.0130879 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0130426 |
| ETNK1 | ethanolamine kinase 1 | -0.0129783 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.012952 |
| YEATS2 | YEATS domain containing 2 | -0.0129355 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.012852 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0127233 |
| CD2AP | CD2-associated protein | -0.0126637 |
| RNF149 | ring finger protein 149 | -0.0125814 |
| EXOC1 | exocyst complex component 1 | -0.0124516 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0124087 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.012359 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0122787 |
| RNF43 | ring finger protein 43 | -0.0120324 |
| FOXB1 | forkhead box B1 | -0.0119909 |
| CDC42SE2 | CDC42 small effector 2 | -0.0119465 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.011895 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | -0.0117664 |
| PCED1B | PC-esterase domain containing 1B | -0.0117052 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0115857 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0115604 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0115293 |
| TPM3 | tropomyosin 3 | -0.0114991 |
| FNIP1 | folliculin interacting protein 1 | -0.0114781 |
| PER3 | period circadian clock 3 | -0.0114676 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0113924 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0113747 |
