| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.241987 |
| AHNAK | AHNAK nucleoprotein | 0.122242 |
| PLEC | plectin | 0.10622 |
| KRT18 | keratin 18, type I | 0.0837734 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0798478 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.071415 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0706889 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0681444 |
| EZR | ezrin | 0.067971 |
| PRELID2 | PRELI domain containing 2 | 0.0656135 |
| KRT8 | keratin 8, type II | 0.065215 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0619337 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0618507 |
| H1-4 | H1.4 linker histone, cluster member | 0.0603299 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0602333 |
| SMYD3 | SET and MYND domain containing 3 | 0.0602045 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0562744 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0554412 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0515503 |
| RPL3 | ribosomal protein L3 | 0.0491873 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0486295 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0484295 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0480457 |
| SDC4 | syndecan 4 | 0.0471167 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0452725 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0451208 |
| SEPTIN9 | septin 9 | 0.0450275 |
| TENM3 | teneurin transmembrane protein 3 | 0.0447232 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0446173 |
| APP | amyloid beta (A4) precursor protein | 0.0444743 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0429789 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0429467 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0409975 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0402633 |
| SFTPA2 | surfactant protein A2 | 0.0394192 |
| TMSB10 | thymosin beta 10 | 0.0392493 |
| MCL1 | myeloid cell leukemia 1 | 0.0392008 |
| FHIT | fragile histidine triad | 0.0391107 |
| FLNA | filamin A, alpha | 0.0382798 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.038004 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0376687 |
| ASPH | aspartate beta-hydroxylase | 0.0376562 |
| NONO | non-POU domain containing, octamer-binding | 0.0375367 |
| RPS3 | ribosomal protein S3 | 0.0361313 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0358061 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0357078 |
| DOCK5 | dedicator of cytokinesis 5 | 0.035523 |
| TJP1 | tight junction protein 1 | 0.0354103 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0353303 |
| JUN | jun proto-oncogene | 0.0351862 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.035151 |
| VCL | vinculin | 0.0350377 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0350136 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0345986 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0344352 |
| RPL35 | ribosomal protein L35 | 0.0338483 |
| RNF213 | ring finger protein 213 | 0.0334605 |
| HYOU1 | hypoxia up-regulated 1 | 0.0320192 |
| SUMF1 | sulfatase modifying factor 1 | 0.0318673 |
| AFDN | afadin, adherens junction formation factor | 0.0318049 |
| RRM2 | ribonucleotide reductase M2 | 0.031056 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0310358 |
| OGA | O-GlcNAcase | 0.0308895 |
| RPS12 | ribosomal protein S12 | 0.0303938 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0295096 |
| H1-2 | H1.2 linker histone, cluster member | 0.0290576 |
| KLC1 | kinesin light chain 1 | 0.0290227 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0289591 |
| FLNB | filamin B, beta | 0.028689 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.028415 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0284149 |
| ATF3 | activating transcription factor 3 | 0.0284119 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0282073 |
| UTRN | utrophin | 0.0281245 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0278503 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0275282 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.027526 |
| RPL13A | ribosomal protein L13a | 0.0271664 |
| SSH2 | slingshot protein phosphatase 2 | 0.0271299 |
| ATXN1 | ataxin 1 | 0.027111 |
| WWC2 | WW and C2 domain containing 2 | 0.027045 |
| CTTN | cortactin | 0.0268477 |
| CALR | calreticulin | 0.0267685 |
| MACROD2 | MACRO domain containing 2 | 0.0267119 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0265788 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0265033 |
| DST | dystonin | 0.0263583 |
| HLA-B | major histocompatibility complex, class I, B | 0.0263341 |
| S100A10 | S100 calcium binding protein A10 | 0.0261351 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0260244 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0259773 |
| GOLGA3 | golgin A3 | 0.0257253 |
| HDLBP | high density lipoprotein binding protein | 0.025381 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.02517 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.025118 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0251122 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0249545 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0249 |
| RPL6 | ribosomal protein L6 | 0.0248819 |
| PARD3B | par-3 family cell polarity regulator beta | 0.024814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.117281 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.116608 |
| NDRG1 | N-myc downstream regulated 1 | -0.0928157 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0846119 |
| GOLGA4 | golgin A4 | -0.077145 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0736338 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0715573 |
| HMGA1 | high mobility group AT-hook 1 | -0.0650395 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0594141 |
| PTMA | prothymosin, alpha | -0.0547837 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0522845 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.049675 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0470611 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0464138 |
| TUBA1B | tubulin, alpha 1b | -0.0447933 |
| SRP54 | signal recognition particle 54kDa | -0.0433874 |
| PCBP2 | poly(rC) binding protein 2 | -0.0432859 |
| RPL35A | ribosomal protein L35a | -0.04016 |
| POTEF | POTE ankyrin domain family, member F | -0.0397782 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0388678 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0378472 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0374346 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0347014 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0344454 |
| WDR45B | WD repeat domain 45B | -0.034434 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0329174 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0319711 |
| NUP58 | nucleoporin 58 | -0.0317796 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0316006 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0313513 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0310341 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0307807 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0298219 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0295717 |
| DIAPH3 | diaphanous-related formin 3 | -0.0284526 |
| WASF2 | WAS protein family, member 2 | -0.0283976 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0278432 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0267113 |
| SEC24A | SEC24 family member A | -0.0265714 |
| LDHB | lactate dehydrogenase B | -0.0264654 |
| MYADM | myeloid-associated differentiation marker | -0.0261703 |
| RPL5 | ribosomal protein L5 | -0.0261199 |
| PFN1 | profilin 1 | -0.0260135 |
| FTL | ferritin, light polypeptide | -0.0256622 |
| HLA-A | major histocompatibility complex, class I, A | -0.0253832 |
| ZNF292 | zinc finger protein 292 | -0.0253612 |
| TMEM123 | transmembrane protein 123 | -0.0245395 |
| LMAN1 | lectin, mannose-binding, 1 | -0.024276 |
| CANX | calnexin | -0.0240424 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0236261 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0235186 |
| CBX3 | chromobox homolog 3 | -0.0232703 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0231978 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0231443 |
| RPLP0 | ribosomal protein, large, P0 | -0.0231052 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0231008 |
| SUCO | SUN domain containing ossification factor | -0.0227956 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0227382 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0226421 |
| TAPBP | TAP binding protein (tapasin) | -0.0224941 |
| YBX1 | Y box binding protein 1 | -0.0222794 |
| RACK1 | receptor for activated C kinase 1 | -0.0220452 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0216915 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0215335 |
| CLDN7 | claudin 7 | -0.0214659 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0212037 |
| GNAS | GNAS complex locus | -0.0211737 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0210028 |
| ENO1 | enolase 1, (alpha) | -0.0208102 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0207695 |
| S100A6 | S100 calcium binding protein A6 | -0.0206976 |
| SMC4 | structural maintenance of chromosomes 4 | -0.020642 |
| MKI67 | marker of proliferation Ki-67 | -0.0206305 |
| RPS6 | ribosomal protein S6 | -0.0203258 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0201425 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0199196 |
| PERP | PERP, TP53 apoptosis effector | -0.0196089 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0195953 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0194185 |
| HOXB9 | homeobox B9 | -0.0193429 |
| COG6 | component of oligomeric golgi complex 6 | -0.0192909 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.018997 |
| MTDH | metadherin | -0.0188916 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0188268 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0187342 |
| SCFD1 | sec1 family domain containing 1 | -0.0186162 |
| ZNF395 | zinc finger protein 395 | -0.018493 |
| RCOR1 | REST corepressor 1 | -0.0182589 |
| PTEN | phosphatase and tensin homolog | -0.0182402 |
| RPS14 | ribosomal protein S14 | -0.0181952 |
| RPL27A | ribosomal protein L27a | -0.018186 |
| SETD5 | SET domain containing 5 | -0.0181305 |
| ATF4 | activating transcription factor 4 | -0.0180215 |
| CERT1 | ceramide transporter 1 | -0.0178726 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0176796 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0174291 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0173665 |
| RPL21 | ribosomal protein L21 | -0.0173649 |
| VEGFA | vascular endothelial growth factor A | -0.0173283 |
| WDR43 | WD repeat domain 43 | -0.0172192 |
