| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.133611 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.127356 |
| APP | amyloid beta (A4) precursor protein | 0.106968 |
| SMAD3 | SMAD family member 3 | 0.099962 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0964779 |
| ACTG1 | actin gamma 1 | 0.0962294 |
| PLEC | plectin | 0.0958772 |
| TMSB4X | thymosin beta 4, X-linked | 0.0908152 |
| TXNRD1 | thioredoxin reductase 1 | 0.0773545 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0766017 |
| AHNAK | AHNAK nucleoprotein | 0.0758664 |
| LAMC2 | laminin, gamma 2 | 0.0672501 |
| MT2A | metallothionein 2A | 0.0668514 |
| ACTN4 | actinin, alpha 4 | 0.0661724 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0610592 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0593816 |
| SNX9 | sorting nexin 9 | 0.057437 |
| ANLN | anillin, actin binding protein | 0.0559906 |
| H1-0 | H1.0 linker histone | 0.0555954 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0542917 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0518694 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.051186 |
| MKI67 | marker of proliferation Ki-67 | 0.0506141 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0488641 |
| SEPTIN9 | septin 9 | 0.0487615 |
| EZR | ezrin | 0.0484049 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.048286 |
| WWC1 | WW and C2 domain containing 1 | 0.0482629 |
| KRT7 | keratin 7, type II | 0.0474735 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0474387 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0466704 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0446645 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0444107 |
| H1-4 | H1.4 linker histone, cluster member | 0.0435266 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0434768 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0432419 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0427872 |
| LAMA4 | laminin, alpha 4 | 0.0425595 |
| B2M | beta-2-microglobulin | 0.0425224 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0424368 |
| MATR3 | matrin 3 | 0.041963 |
| SFTPA2 | surfactant protein A2 | 0.0415094 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0414749 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0405277 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0400911 |
| CLTC | clathrin, heavy chain (Hc) | 0.0394648 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0389816 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0385968 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0379711 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0378192 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0377029 |
| ECT2 | epithelial cell transforming 2 | 0.0376889 |
| OGA | O-GlcNAcase | 0.0371055 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0366595 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.036512 |
| ANXA2 | annexin A2 | 0.0360224 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.03562 |
| CANX | calnexin | 0.0353481 |
| LMNA | lamin A/C | 0.035268 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0347705 |
| HELZ | helicase with zinc finger | 0.0346843 |
| YEATS2 | YEATS domain containing 2 | 0.0341259 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0338927 |
| ANXA1 | annexin A1 | 0.0338837 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0336758 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0334385 |
| EMP1 | epithelial membrane protein 1 | 0.0332351 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0331323 |
| PGK1 | phosphoglycerate kinase 1 | 0.0330306 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0329238 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0327923 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.03168 |
| APOL1 | apolipoprotein L, 1 | 0.0315963 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0313936 |
| TUBB | tubulin, beta class I | 0.031347 |
| VCL | vinculin | 0.0313438 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0308215 |
| FOSL1 | FOS-like antigen 1 | 0.0305238 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0303906 |
| WDR45B | WD repeat domain 45B | 0.0303214 |
| RPLP0 | ribosomal protein, large, P0 | 0.0303137 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0301328 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.030091 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0298796 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0297033 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0294234 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0292726 |
| YBX3 | Y box binding protein 3 | 0.0289769 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0284367 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282897 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.028166 |
| TPM4 | tropomyosin 4 | 0.0276872 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0276336 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0272982 |
| PTMA | prothymosin, alpha | 0.0272689 |
| RNF145 | ring finger protein 145 | 0.0271324 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0270209 |
| KLF6 | Kruppel-like factor 6 | 0.0269353 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0267119 |
| XPO1 | exportin 1 | 0.0266604 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS12 | ribosomal protein S12 | -0.0813991 |
| RPL37A | ribosomal protein L37a | -0.0650624 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.063951 |
| RAD51B | RAD51 paralog B | -0.0596519 |
| TMSB10 | thymosin beta 10 | -0.0553694 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0547423 |
| INTS6 | integrator complex subunit 6 | -0.0520607 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0509704 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0494881 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0458715 |
| RPL28 | ribosomal protein L28 | -0.0454995 |
| FHIT | fragile histidine triad | -0.0429952 |
| RPS29 | ribosomal protein S29 | -0.0413316 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0392392 |
| RPL31 | ribosomal protein L31 | -0.0389808 |
| PRELID2 | PRELI domain containing 2 | -0.0381521 |
| EGFR | epidermal growth factor receptor | -0.0370357 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0360691 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.035868 |
| CCDC138 | coiled-coil domain containing 138 | -0.0355633 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0347826 |
| RPS17 | ribosomal protein S17 | -0.0341389 |
| RPL35 | ribosomal protein L35 | -0.0339425 |
| RPS3 | ribosomal protein S3 | -0.0333476 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0327901 |
| HMGA2 | high mobility group AT-hook 2 | -0.0320721 |
| RPLP2 | ribosomal protein, large, P2 | -0.0320357 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0319834 |
| RPS23 | ribosomal protein S23 | -0.0317892 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0315662 |
| RPS8 | ribosomal protein S8 | -0.0312546 |
| RPL9 | ribosomal protein L9 | -0.0303946 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0303551 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0299024 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0291523 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0291449 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0287801 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0285048 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0282254 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0279359 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0278481 |
| AGRN | agrin | -0.02728 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0272736 |
| ATXN1 | ataxin 1 | -0.027094 |
| GPR39 | G protein-coupled receptor 39 | -0.0267347 |
| RPS25 | ribosomal protein S25 | -0.0266159 |
| NABP1 | nucleic acid binding protein 1 | -0.0259899 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0259744 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.025721 |
| RPS13 | ribosomal protein S13 | -0.0254422 |
| GPATCH2L | G patch domain containing 2-like | -0.0252811 |
| RPS15 | ribosomal protein S15 | -0.0250571 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0248759 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0247546 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0245598 |
| RPS11 | ribosomal protein S11 | -0.0243666 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0236884 |
| RTN3 | reticulon 3 | -0.0235049 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0235043 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0232037 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -0.023085 |
| GLIS3 | GLIS family zinc finger 3 | -0.0230521 |
| SPATA13 | spermatogenesis associated 13 | -0.0225395 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0224288 |
| RPS10 | ribosomal protein S10 | -0.0221615 |
| PCED1B | PC-esterase domain containing 1B | -0.0221525 |
| SNX14 | sorting nexin 14 | -0.0220099 |
| UBAP2 | ubiquitin associated protein 2 | -0.0219394 |
| KRT86 | keratin 86, type II | -0.0219228 |
| RPL36 | ribosomal protein L36 | -0.0216616 |
| AEBP2 | AE binding protein 2 | -0.0215196 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0214786 |
| MACROD2 | MACRO domain containing 2 | -0.0213824 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0210329 |
| PLCB4 | phospholipase C, beta 4 | -0.0208885 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0204995 |
| RCOR1 | REST corepressor 1 | -0.0201387 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0198774 |
| UGT2B7 | UDP glucuronosyltransferase 2 family, polypeptide B7 | -0.0197914 |
| RPS27A | ribosomal protein S27a | -0.0197059 |
| HELLS | helicase, lymphoid-specific | -0.0196165 |
| SHISA5 | shisa family member 5 | -0.0195421 |
| ATG7 | autophagy related 7 | -0.0194475 |
| PCNX4 | pecanex 4 | -0.0194135 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0191558 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0190822 |
| ASPH | aspartate beta-hydroxylase | -0.0190359 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0189992 |
| ERBIN | erbb2 interacting protein | -0.0188604 |
| HMGA1 | high mobility group AT-hook 1 | -0.0188234 |
| PHF3 | PHD finger protein 3 | -0.018773 |
| TBCA | tubulin folding cofactor A | -0.0187372 |
| WDR49 | WD repeat domain 49 | -0.0187335 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0186359 |
| RPL13A | ribosomal protein L13a | -0.0183404 |
| LAMA5 | laminin, alpha 5 | -0.0182745 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0182396 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.018234 |
| TRIM25 | tripartite motif containing 25 | -0.0181758 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0180368 |
