| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.413353 |
| COL6A3 | collagen, type VI, alpha 3 | 0.182421 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.114885 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0967379 |
| STC1 | stanniocalcin 1 | 0.0889104 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0756975 |
| CD44 | CD44 molecule (Indian blood group) | 0.0687142 |
| LOXL2 | lysyl oxidase-like 2 | 0.0607431 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0566817 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0563803 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0561691 |
| COL1A2 | collagen, type I, alpha 2 | 0.0556473 |
| MT2A | metallothionein 2A | 0.0507206 |
| PLEC | plectin | 0.0489987 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0469639 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0467548 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0429065 |
| VIM | vimentin | 0.0423194 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0418671 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0416385 |
| INHBA | inhibin, beta A | 0.0409363 |
| HMGA2 | high mobility group AT-hook 2 | 0.0406508 |
| CLIC4 | chloride intracellular channel 4 | 0.0394887 |
| VEGFA | vascular endothelial growth factor A | 0.0386072 |
| TPM4 | tropomyosin 4 | 0.0367388 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0362567 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0362153 |
| ASPH | aspartate beta-hydroxylase | 0.0358053 |
| POSTN | periostin, osteoblast specific factor | 0.0333221 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0305203 |
| TMSB4X | thymosin beta 4, X-linked | 0.0299987 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0299273 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0280118 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0279737 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.027727 |
| APP | amyloid beta (A4) precursor protein | 0.0275445 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0266658 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0260877 |
| UBC | ubiquitin C | 0.0260042 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0257447 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0256254 |
| ECE1 | endothelin converting enzyme 1 | 0.0255601 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.025495 |
| FBN1 | fibrillin 1 | 0.0251131 |
| COL3A1 | collagen, type III, alpha 1 | 0.0246491 |
| MT1X | metallothionein 1X | 0.0242568 |
| CTSB | cathepsin B | 0.0232872 |
| LDHA | lactate dehydrogenase A | 0.023241 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.022611 |
| CALU | calumenin | 0.0225246 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0224763 |
| CALR | calreticulin | 0.0215997 |
| IL6 | interleukin 6 | 0.0215325 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0213734 |
| CLMP | CXADR-like membrane protein | 0.0205101 |
| OSMR | oncostatin M receptor | 0.0203598 |
| GLIS3 | GLIS family zinc finger 3 | 0.0203515 |
| ARRDC3 | arrestin domain containing 3 | 0.0200612 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0198877 |
| NRP1 | neuropilin 1 | 0.0198781 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0196309 |
| MTSS1 | metastasis suppressor 1 | 0.0190397 |
| NAV1 | neuron navigator 1 | 0.0189813 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0188295 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0184671 |
| SQLE | squalene epoxidase | 0.0181938 |
| AHNAK | AHNAK nucleoprotein | 0.0179813 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.017967 |
| IL6ST | interleukin 6 signal transducer | 0.0177548 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0177166 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0176441 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0175473 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0173639 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0173231 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.017086 |
| MAP1B | microtubule-associated protein 1B | 0.0168151 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0165836 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0165676 |
| SFTPA2 | surfactant protein A2 | 0.0164393 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0161673 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0160196 |
| DUSP6 | dual specificity phosphatase 6 | 0.0160005 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.01581 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0153079 |
| TUBB | tubulin, beta class I | 0.0150834 |
| CANX | calnexin | 0.0150511 |
| RND3 | Rho family GTPase 3 | 0.0149211 |
| SMAD3 | SMAD family member 3 | 0.0148258 |
| TAGLN2 | transgelin 2 | 0.0147369 |
| B2M | beta-2-microglobulin | 0.014591 |
| HAS2 | hyaluronan synthase 2 | 0.01455 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0142603 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0137158 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.013419 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0131018 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.013078 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0128382 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0127831 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0127373 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0126619 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.128184 |
| CADM1 | cell adhesion molecule 1 | -0.11309 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0572547 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0572114 |
| TMSB10 | thymosin beta 10 | -0.0469567 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0452478 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0444745 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0431747 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0422104 |
| PDE10A | phosphodiesterase 10A | -0.0386855 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0349755 |
| COL1A1 | collagen, type I, alpha 1 | -0.0347764 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0344645 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0343088 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0302449 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0294844 |
| CDH13 | cadherin 13 | -0.0293612 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0288002 |
| EGFR | epidermal growth factor receptor | -0.0283432 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0269304 |
| CD109 | CD109 molecule | -0.0268187 |
| RPL37A | ribosomal protein L37a | -0.0256764 |
| RUNX1 | runt-related transcription factor 1 | -0.0247545 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0236161 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0234494 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0224554 |
| ATXN1 | ataxin 1 | -0.0222914 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0214548 |
| QKI | QKI, KH domain containing, RNA binding | -0.0213892 |
| RPS3 | ribosomal protein S3 | -0.0207615 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0206075 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0204278 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0197838 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0196523 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0194734 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0194019 |
| AFF4 | AF4/FMR2 family, member 4 | -0.019307 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0192564 |
| RBM39 | RNA binding motif protein 39 | -0.019175 |
| PRR16 | proline rich 16 | -0.0184374 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.018313 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0182692 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0171323 |
| COPA | coatomer protein complex, subunit alpha | -0.0171304 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0170705 |
| CALD1 | caldesmon 1 | -0.017065 |
| TFG | TRK-fused gene | -0.0166725 |
| PRELID2 | PRELI domain containing 2 | -0.0166558 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0164834 |
| GOLGA4 | golgin A4 | -0.0164194 |
| MTDH | metadherin | -0.0161754 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0158935 |
| SBF2 | SET binding factor 2 | -0.015562 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0155067 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.015485 |
| CNTN5 | contactin 5 | -0.0154599 |
| COL5A1 | collagen, type V, alpha 1 | -0.0153204 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0152723 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0148989 |
| KIF13A | kinesin family member 13A | -0.0148706 |
| RPLP2 | ribosomal protein, large, P2 | -0.0147622 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0147464 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0146989 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0146801 |
| FNIP1 | folliculin interacting protein 1 | -0.014279 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0140803 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0140499 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0139728 |
| NOTCH2 | notch 2 | -0.0136967 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0135827 |
| RPL28 | ribosomal protein L28 | -0.0135821 |
| BBX | bobby sox homolog (Drosophila) | -0.0134274 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0134234 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0134124 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.013404 |
| CDON | cell adhesion associated, oncogene regulated | -0.0134029 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0132221 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0131627 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0130543 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.012829 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0128212 |
| EPHB1 | EPH receptor B1 | -0.012817 |
| HELZ | helicase with zinc finger | -0.012707 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.012609 |
| ZNF292 | zinc finger protein 292 | -0.0126021 |
| TENM3 | teneurin transmembrane protein 3 | -0.0125087 |
| PHF21A | PHD finger protein 21A | -0.0124895 |
| RPS12 | ribosomal protein S12 | -0.012488 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0123615 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0123128 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0122619 |
| FMNL2 | formin-like 2 | -0.0122518 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0119868 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0118787 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0118511 |
| STC2 | stanniocalcin 2 | -0.011759 |
| DST | dystonin | -0.0117583 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0115374 |
| NBAS | neuroblastoma amplified sequence | -0.0115023 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.011488 |
