| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.128414 |
| AHNAK | AHNAK nucleoprotein | 0.122191 |
| KRT8 | keratin 8, type II | 0.115535 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.110811 |
| EXT1 | exostosin glycosyltransferase 1 | 0.108737 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0986433 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.090891 |
| KRT18 | keratin 18, type I | 0.0794528 |
| PLEC | plectin | 0.0741496 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0713586 |
| FAT1 | FAT atypical cadherin 1 | 0.070426 |
| EMP1 | epithelial membrane protein 1 | 0.0703714 |
| EXPH5 | exophilin 5 | 0.0695705 |
| SMAD3 | SMAD family member 3 | 0.062139 |
| HYOU1 | hypoxia up-regulated 1 | 0.0597813 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0596166 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0591071 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0585806 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0542002 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0535371 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0526241 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0523014 |
| RPL3 | ribosomal protein L3 | 0.051717 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0500389 |
| RPS3 | ribosomal protein S3 | 0.0494268 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0487802 |
| JMJD1C | jumonji domain containing 1C | 0.048778 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0467464 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0454081 |
| RPL4 | ribosomal protein L4 | 0.0450564 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0445635 |
| ATF3 | activating transcription factor 3 | 0.0438494 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0424968 |
| MYO5B | myosin VB | 0.0423239 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0414173 |
| NEBL | nebulette | 0.0411017 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0402281 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 0.0393058 |
| SFTPA2 | surfactant protein A2 | 0.0392834 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0384297 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0383731 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0382593 |
| HSPA8 | heat shock 70kDa protein 8 | 0.038052 |
| EZR | ezrin | 0.0379593 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0378538 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0376548 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0375516 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0374496 |
| RPL13A | ribosomal protein L13a | 0.0372404 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0364534 |
| GOLGB1 | golgin B1 | 0.0358944 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0349876 |
| SEPTIN9 | septin 9 | 0.0346913 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0340153 |
| CTTN | cortactin | 0.0335641 |
| RPS12 | ribosomal protein S12 | 0.0324167 |
| SHROOM3 | shroom family member 3 | 0.0322062 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0317616 |
| CALR | calreticulin | 0.0317265 |
| H1-4 | H1.4 linker histone, cluster member | 0.0309361 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0308216 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.030782 |
| RPS15A | ribosomal protein S15a | 0.029711 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0296619 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0294885 |
| TMEM65 | transmembrane protein 65 | 0.029435 |
| APP | amyloid beta (A4) precursor protein | 0.0293217 |
| CTBP2 | C-terminal binding protein 2 | 0.0288326 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0287636 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0286964 |
| CPNE1 | copine I | 0.0286363 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.028582 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0285321 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0284633 |
| NONO | non-POU domain containing, octamer-binding | 0.0280781 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0280649 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.027949 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0276655 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0276127 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0274376 |
| RPL19 | ribosomal protein L19 | 0.0273428 |
| AFDN | afadin, adherens junction formation factor | 0.0273169 |
| LMNA | lamin A/C | 0.0271699 |
| ANXA1 | annexin A1 | 0.0267653 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0267515 |
| ATXN1 | ataxin 1 | 0.0267245 |
| DSPP | dentin sialophosphoprotein | 0.0266368 |
| H1-0 | H1.0 linker histone | 0.026418 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0263292 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.026303 |
| DNMBP | dynamin binding protein | 0.0258143 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0255052 |
| FOXP1 | forkhead box P1 | 0.0249776 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0247496 |
| NCKAP1 | NCK-associated protein 1 | 0.0246062 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0245341 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0244576 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0244168 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0242565 |
| RPL37A | ribosomal protein L37a | 0.0241418 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.21594 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.141852 |
| EGR1 | early growth response 1 | -0.115774 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.114524 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0995159 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0860321 |
| VCL | vinculin | -0.084705 |
| LYZ | lysozyme | -0.0761879 |
| TXNRD1 | thioredoxin reductase 1 | -0.0759584 |
| ANXA2 | annexin A2 | -0.0722023 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0694958 |
| FTL | ferritin, light polypeptide | -0.0688634 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0687455 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0662819 |
| FRY | furry homolog (Drosophila) | -0.065863 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0657829 |
| HMGA1 | high mobility group AT-hook 1 | -0.063829 |
| RPL35A | ribosomal protein L35a | -0.0633852 |
| S100A6 | S100 calcium binding protein A6 | -0.0546277 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.053617 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0529374 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0503362 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0500538 |
| WASF2 | WAS protein family, member 2 | -0.0488883 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0486732 |
| POTEF | POTE ankyrin domain family, member F | -0.0474017 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0471485 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0463829 |
| INTS6 | integrator complex subunit 6 | -0.0457447 |
| LIMA1 | LIM domain and actin binding 1 | -0.0456533 |
| GOLGA4 | golgin A4 | -0.0456002 |
| NDRG1 | N-myc downstream regulated 1 | -0.0452288 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0446699 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0431073 |
| MMP7 | matrix metallopeptidase 7 | -0.0421539 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0421212 |
| RPS6 | ribosomal protein S6 | -0.0419041 |
| RPL27A | ribosomal protein L27a | -0.0418807 |
| FOSL1 | FOS-like antigen 1 | -0.0417398 |
| DIAPH2 | diaphanous-related formin 2 | -0.0417374 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0414023 |
| DGKH | diacylglycerol kinase, eta | -0.0402953 |
| RPLP0 | ribosomal protein, large, P0 | -0.0397685 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0393227 |
| ACTN4 | actinin, alpha 4 | -0.038884 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0383426 |
| TJP1 | tight junction protein 1 | -0.03824 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0379119 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0366585 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0365726 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0363077 |
| LDHA | lactate dehydrogenase A | -0.0356027 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0354582 |
| HKDC1 | hexokinase domain containing 1 | -0.035409 |
| JUN | jun proto-oncogene | -0.0347942 |
| ZFP36 | ZFP36 ring finger protein | -0.03468 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0346573 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0340878 |
| MUC13 | mucin 13, cell surface associated | -0.0331215 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0331174 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0328925 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0326773 |
| RPS19 | ribosomal protein S19 | -0.0325906 |
| PTMA | prothymosin, alpha | -0.0323114 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0322387 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0317306 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0316908 |
| RPL23 | ribosomal protein L23 | -0.0312249 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0311973 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0310258 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0306048 |
| GNAS | GNAS complex locus | -0.0302413 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0293932 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0292136 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.028878 |
| MAGT1 | magnesium transporter 1 | -0.0286807 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0281566 |
| AGR2 | anterior gradient 2 | -0.02815 |
| DSTN | destrin (actin depolymerizing factor) | -0.02807 |
| SQSTM1 | sequestosome 1 | -0.0280601 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.027933 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0275683 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0275534 |
| RTN3 | reticulon 3 | -0.0275157 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0274883 |
| RPS25 | ribosomal protein S25 | -0.0271458 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0269903 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0269871 |
| ZNF609 | zinc finger protein 609 | -0.0266304 |
| RPL21 | ribosomal protein L21 | -0.0266256 |
| TRAM1 | translocation associated membrane protein 1 | -0.0266033 |
| CLDN4 | claudin 4 | -0.0265005 |
| JUP | junction plakoglobin | -0.0264116 |
| PATJ | PATJ crumbs cell polarity complex component | -0.02625 |
| SQLE | squalene epoxidase | -0.0260862 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.026076 |
| RBM47 | RNA binding motif protein 47 | -0.0260707 |
| ANXA3 | annexin A3 | -0.026014 |
| RSF1 | remodeling and spacing factor 1 | -0.0258984 |
| RPL39 | ribosomal protein L39 | -0.0257612 |
