| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.24608 |
| DSPP | dentin sialophosphoprotein | 0.14663 |
| ENO1 | enolase 1, (alpha) | 0.145239 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.14031 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.129941 |
| SVIL | supervillin | 0.128845 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.114004 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.111373 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.106553 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103341 |
| FN1 | fibronectin 1 | 0.101319 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.10052 |
| ASPH | aspartate beta-hydroxylase | 0.0881372 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0827702 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0732455 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0730511 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0729737 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0718811 |
| ATXN1 | ataxin 1 | 0.067113 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0666768 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0657178 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0642661 |
| FAM107B | family with sequence similarity 107, member B | 0.0624126 |
| UBC | ubiquitin C | 0.0613612 |
| PEG3 | paternally expressed 3 | 0.0585461 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0580252 |
| FRMD5 | FERM domain containing 5 | 0.0570684 |
| FLNB | filamin B, beta | 0.0543284 |
| RPS27A | ribosomal protein S27a | 0.052368 |
| NDRG1 | N-myc downstream regulated 1 | 0.0516989 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0475951 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0473505 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0461682 |
| FOXP1 | forkhead box P1 | 0.0453179 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0437043 |
| AHNAK | AHNAK nucleoprotein | 0.0432448 |
| CANX | calnexin | 0.0432104 |
| LDHA | lactate dehydrogenase A | 0.0426825 |
| KRT8 | keratin 8, type II | 0.0406214 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0396932 |
| PLEC | plectin | 0.0395409 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0391541 |
| TNS1 | tensin 1 | 0.0389733 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0389365 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.038856 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0385606 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0385374 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0382561 |
| EHBP1 | EH domain binding protein 1 | 0.0379241 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0374603 |
| FAT1 | FAT atypical cadherin 1 | 0.0374346 |
| RPL3 | ribosomal protein L3 | 0.0366746 |
| KYNU | kynureninase | 0.036067 |
| AHSG | alpha-2-HS-glycoprotein | 0.0355986 |
| TMSB10 | thymosin beta 10 | 0.034356 |
| RPL23 | ribosomal protein L23 | 0.0331621 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0329695 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0329236 |
| SDC4 | syndecan 4 | 0.0328588 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0326429 |
| KRT18 | keratin 18, type I | 0.0322808 |
| MCL1 | myeloid cell leukemia 1 | 0.0308461 |
| JUN | jun proto-oncogene | 0.0303389 |
| ATF3 | activating transcription factor 3 | 0.0303145 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0302224 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0301644 |
| HDLBP | high density lipoprotein binding protein | 0.0300155 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0294849 |
| RAD51B | RAD51 paralog B | 0.0290537 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0287642 |
| ARFGEF3 | ARFGEF family member 3 | 0.0286683 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0286208 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0285844 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0284122 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.027992 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0279313 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0277391 |
| RNF213 | ring finger protein 213 | 0.0277367 |
| KIAA1217 | KIAA1217 | 0.0275366 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0275361 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0275181 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0274295 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0274194 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0272963 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.02723 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0271757 |
| SFTPA2 | surfactant protein A2 | 0.02715 |
| FAM13A | family with sequence similarity 13, member A | 0.0258402 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0257937 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0255114 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0253433 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0253012 |
| PKM | pyruvate kinase, muscle | 0.0252298 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0251834 |
| FMNL2 | formin-like 2 | 0.0250747 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.02498 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0248136 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.024703 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.024671 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0246574 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.294078 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.1273 |
| C3 | complement component 3 | -0.0663642 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0412446 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.039161 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0380077 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0358853 |
| RBM25 | RNA binding motif protein 25 | -0.0356547 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0352502 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0304653 |
| VCL | vinculin | -0.029928 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0290294 |
| EGR1 | early growth response 1 | -0.028571 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0262681 |
| ZNF644 | zinc finger protein 644 | -0.0241262 |
| APOA2 | apolipoprotein A-II | -0.0227506 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0225687 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0221723 |
| RBM39 | RNA binding motif protein 39 | -0.0219539 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0212492 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0205989 |
| APOB | apolipoprotein B | -0.0204439 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0203129 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0196933 |
| CCNL1 | cyclin L1 | -0.0196152 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0195333 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0193742 |
| QKI | QKI, KH domain containing, RNA binding | -0.0183255 |
| PTCHD4 | patched domain containing 4 | -0.0181896 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0178005 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0177955 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0173364 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.017225 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0169715 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.0169389 |
| A2M | alpha-2-macroglobulin | -0.016793 |
| GDF15 | growth differentiation factor 15 | -0.0165401 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0164381 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0160833 |
| TMEM123 | transmembrane protein 123 | -0.0156782 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0155415 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0154166 |
| GNAS | GNAS complex locus | -0.01494 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0148921 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0145343 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0145117 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0145057 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0142611 |
| LYZ | lysozyme | -0.0139436 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.0137638 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0136008 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0134315 |
| LARP4 | La ribonucleoprotein domain family, member 4 | -0.0133644 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | -0.013205 |
| PCBP2 | poly(rC) binding protein 2 | -0.0129854 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0128674 |
| POU2F1 | POU class 2 homeobox 1 | -0.0127282 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0127243 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0126952 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0124845 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.0124305 |
| MRTFA | myocardin related transcription factor A | -0.0122959 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0122827 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | -0.0122087 |
| RNF11 | ring finger protein 11 | -0.0121565 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0120127 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0120044 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0119906 |
| ZFP36 | ZFP36 ring finger protein | -0.011892 |
| RTN4 | reticulon 4 | -0.0117012 |
| OLA1 | Obg-like ATPase 1 | -0.0116263 |
| MATN3 | matrilin 3 | -0.0115292 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0115194 |
| KIF5B | kinesin family member 5B | -0.0114069 |
| CALD1 | caldesmon 1 | -0.0112839 |
| RPL35A | ribosomal protein L35a | -0.0111812 |
| HMGA1 | high mobility group AT-hook 1 | -0.011057 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0110155 |
| ARHGAP9 | Rho GTPase activating protein 9 | -0.0110131 |
| FKTN | fukutin | -0.0110097 |
| PDS5B | PDS5 cohesin associated factor B | -0.0110005 |
| CUL3 | cullin 3 | -0.0109276 |
| WTAP | Wilms tumor 1 associated protein | -0.0109264 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0107794 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0107019 |
| AGRN | agrin | -0.0106263 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.0105524 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | -0.0104921 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0104851 |
| TMEM51 | transmembrane protein 51 | -0.0104519 |
| RDX | radixin | -0.010442 |
| DHFR | dihydrofolate reductase | -0.01042 |
| UBXN4 | UBX domain protein 4 | -0.0103846 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0103622 |
| PFN1 | profilin 1 | -0.0103013 |
| ATP13A3 | ATPase type 13A3 | -0.0102618 |
| CCDC146 | coiled-coil domain containing 146 | -0.0102403 |
| ATAD2B | ATPase family, AAA domain containing 2B | -0.0101089 |
| YAP1 | Yes-associated protein 1 | -0.0100957 |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl | -0.0100306 |
