| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0759625 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0684787 |
| PLEC | plectin | 0.0624251 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0606758 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0565277 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.055876 |
| AHNAK | AHNAK nucleoprotein | 0.0548633 |
| MT2A | metallothionein 2A | 0.0537103 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0519168 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0517609 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.051386 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.048864 |
| TMSB4X | thymosin beta 4, X-linked | 0.0478965 |
| OSMR | oncostatin M receptor | 0.046991 |
| LMO7 | LIM domain 7 | 0.0463364 |
| ASPH | aspartate beta-hydroxylase | 0.0455989 |
| MTSS1 | metastasis suppressor 1 | 0.0437164 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0436272 |
| HLA-B | major histocompatibility complex, class I, B | 0.0435394 |
| RPS21 | ribosomal protein S21 | 0.042186 |
| RPLP2 | ribosomal protein, large, P2 | 0.0420702 |
| FOXP1 | forkhead box P1 | 0.0417508 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.038704 |
| EFNA5 | ephrin-A5 | 0.0381556 |
| RPLP1 | ribosomal protein, large, P1 | 0.0373386 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0365214 |
| CD44 | CD44 molecule (Indian blood group) | 0.035474 |
| TMSB10 | thymosin beta 10 | 0.0326519 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0322624 |
| RIN2 | Ras and Rab interactor 2 | 0.0316985 |
| AOPEP | aminopeptidase O (putative) | 0.0315653 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0312359 |
| SMAD3 | SMAD family member 3 | 0.0301466 |
| RAD51B | RAD51 paralog B | 0.0296395 |
| B2M | beta-2-microglobulin | 0.0294679 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0294467 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0294335 |
| TXNIP | thioredoxin interacting protein | 0.0292612 |
| CDK6 | cyclin-dependent kinase 6 | 0.0287789 |
| HMGA2 | high mobility group AT-hook 2 | 0.0286583 |
| FOXO1 | forkhead box O1 | 0.0286433 |
| RPS6 | ribosomal protein S6 | 0.0285571 |
| PRSS23 | protease, serine, 23 | 0.0283204 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0280131 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0276673 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0273671 |
| RPL11 | ribosomal protein L11 | 0.026727 |
| LAMC2 | laminin, gamma 2 | 0.0264974 |
| SMYD3 | SET and MYND domain containing 3 | 0.0264953 |
| RPS24 | ribosomal protein S24 | 0.0263032 |
| PLAT | plasminogen activator, tissue | 0.0261673 |
| RPS19 | ribosomal protein S19 | 0.0259345 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.025922 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0258154 |
| RIGI | RNA sensor RIG-I | 0.0256985 |
| SULF2 | sulfatase 2 | 0.0255945 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0246961 |
| SEPTIN9 | septin 9 | 0.0243963 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0242882 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0241603 |
| RPS13 | ribosomal protein S13 | 0.0240728 |
| RPL37 | ribosomal protein L37 | 0.0237175 |
| RPS12 | ribosomal protein S12 | 0.0236198 |
| RPL26 | ribosomal protein L26 | 0.0235433 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0234409 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0233887 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0233031 |
| RPL37A | ribosomal protein L37a | 0.0230828 |
| PRELID2 | PRELI domain containing 2 | 0.0230812 |
| BLCAP | bladder cancer associated protein | 0.0228382 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0226945 |
| MECOM | MDS1 and EVI1 complex locus | 0.0225475 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0221028 |
| AMOTL1 | angiomotin like 1 | 0.0219462 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0218684 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0218294 |
| RPL7A | ribosomal protein L7a | 0.0217182 |
| DST | dystonin | 0.0214877 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0214056 |
| RPL23 | ribosomal protein L23 | 0.0210343 |
| RPS8 | ribosomal protein S8 | 0.0209891 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0209772 |
| RPS3 | ribosomal protein S3 | 0.0207769 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0204772 |
| APP | amyloid beta (A4) precursor protein | 0.0204491 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0202393 |
| RASAL2 | RAS protein activator like 2 | 0.0200746 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0200366 |
| DUSP4 | dual specificity phosphatase 4 | 0.0198484 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0198226 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0196245 |
| ATXN1 | ataxin 1 | 0.0196056 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0193342 |
| EXOC4 | exocyst complex component 4 | 0.0191845 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0191283 |
| RPS27 | ribosomal protein S27 | 0.0191074 |
| MTAP | methylthioadenosine phosphorylase | 0.0190522 |
| TXNRD1 | thioredoxin reductase 1 | 0.0188626 |
| IFI44L | interferon-induced protein 44-like | 0.0188097 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0188006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.082639 |
| MEF2A | myocyte enhancer factor 2A | -0.078586 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0648507 |
| GOLGA4 | golgin A4 | -0.058627 |
| SQLE | squalene epoxidase | -0.0575401 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0511474 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0469161 |
| POTEF | POTE ankyrin domain family, member F | -0.0465624 |
| ANXA1 | annexin A1 | -0.0398073 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0390562 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.03707 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0320639 |
| COPA | coatomer protein complex, subunit alpha | -0.0310054 |
| SPAG9 | sperm associated antigen 9 | -0.0308525 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0305843 |
| SUCO | SUN domain containing ossification factor | -0.0300583 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0298841 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0297877 |
| DSTN | destrin (actin depolymerizing factor) | -0.0297412 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0297315 |
| WASF2 | WAS protein family, member 2 | -0.0294474 |
| SRP54 | signal recognition particle 54kDa | -0.0293737 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0293565 |
| PLS3 | plastin 3 | -0.0286495 |
| RBM39 | RNA binding motif protein 39 | -0.0274848 |
| MORF4L2 | mortality factor 4 like 2 | -0.0266423 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0263069 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0256892 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0253483 |
| STC1 | stanniocalcin 1 | -0.024869 |
| HELZ | helicase with zinc finger | -0.0247989 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0245471 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | -0.0238438 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0237813 |
| KRT6A | keratin 6A, type II | -0.02373 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.023695 |
| TAGLN2 | transgelin 2 | -0.0233352 |
| TFG | TRK-fused gene | -0.0231527 |
| TMEM165 | transmembrane protein 165 | -0.0230384 |
| PGK1 | phosphoglycerate kinase 1 | -0.0230296 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.022704 |
| INSIG2 | insulin induced gene 2 | -0.0225677 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.022359 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0222811 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0222051 |
| SULF1 | sulfatase 1 | -0.0221719 |
| RNF145 | ring finger protein 145 | -0.022037 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0218975 |
| NUP58 | nucleoporin 58 | -0.0218228 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0216706 |
| PCBP2 | poly(rC) binding protein 2 | -0.0215363 |
| IGF2 | insulin-like growth factor 2 | -0.0215302 |
| COG6 | component of oligomeric golgi complex 6 | -0.0214329 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.021139 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0209694 |
| FOXO3 | forkhead box O3 | -0.0208122 |
| UFM1 | ubiquitin-fold modifier 1 | -0.020808 |
| LDHA | lactate dehydrogenase A | -0.0207571 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0207158 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0205718 |
| ARF4 | ADP-ribosylation factor 4 | -0.0201359 |
| KRT17 | keratin 17, type I | -0.0198453 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0196657 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0192823 |
| YBX1 | Y box binding protein 1 | -0.0192755 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0192381 |
| LAMA5 | laminin, alpha 5 | -0.0191447 |
| GLYAT | glycine-N-acyltransferase | -0.0190775 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0186521 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0186015 |
| CALU | calumenin | -0.0180852 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0179901 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0177917 |
| RIOK3 | RIO kinase 3 | -0.017782 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0174677 |
| FAM13A | family with sequence similarity 13, member A | -0.0173432 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0172002 |
| SEC24A | SEC24 family member A | -0.017103 |
| SLMAP | sarcolemma associated protein | -0.0170384 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0166882 |
| TRAM1 | translocation associated membrane protein 1 | -0.0166035 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0165694 |
| SETD5 | SET domain containing 5 | -0.0165667 |
| EZR | ezrin | -0.0165075 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0164554 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0164168 |
| PKM | pyruvate kinase, muscle | -0.0163517 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0161418 |
| EFHD2 | EF-hand domain family, member D2 | -0.0160055 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0159529 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0158925 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0158773 |
| USP3 | ubiquitin specific peptidase 3 | -0.0157813 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0157639 |
| FOSL1 | FOS-like antigen 1 | -0.0155316 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0154634 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0153789 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0153543 |
| ANXA2 | annexin A2 | -0.0153364 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0152197 |
