| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.132318 |
| EXT1 | exostosin glycosyltransferase 1 | 0.12371 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.118845 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.111463 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0999106 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0817423 |
| MT2A | metallothionein 2A | 0.0805176 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0699273 |
| ASPH | aspartate beta-hydroxylase | 0.0656911 |
| CD44 | CD44 molecule (Indian blood group) | 0.0646083 |
| ERBIN | erbb2 interacting protein | 0.0550286 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0526294 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0514935 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0474497 |
| DST | dystonin | 0.0474291 |
| FLNB | filamin B, beta | 0.0447094 |
| AHNAK | AHNAK nucleoprotein | 0.0441458 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0441195 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.043907 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0414841 |
| ENO1 | enolase 1, (alpha) | 0.0414812 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0405299 |
| MSN | moesin | 0.0392574 |
| ACTG1 | actin gamma 1 | 0.0384975 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0365396 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0360557 |
| VIM | vimentin | 0.0345928 |
| ACTN1 | actinin, alpha 1 | 0.0342213 |
| HLA-B | major histocompatibility complex, class I, B | 0.0337593 |
| PODXL | podocalyxin-like | 0.0337534 |
| TMSB10 | thymosin beta 10 | 0.0331117 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0322936 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.032168 |
| PTK2 | protein tyrosine kinase 2 | 0.0320476 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0317228 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0312222 |
| SMYD3 | SET and MYND domain containing 3 | 0.0308485 |
| NAV2 | neuron navigator 2 | 0.0301969 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0297019 |
| RPS6 | ribosomal protein S6 | 0.0296288 |
| SET | SET nuclear proto-oncogene | 0.0292401 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0290616 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0289787 |
| VCL | vinculin | 0.0286992 |
| RAI14 | retinoic acid induced 14 | 0.0286447 |
| INTS6 | integrator complex subunit 6 | 0.0281184 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0273182 |
| TPM1 | tropomyosin 1 (alpha) | 0.0269883 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0264688 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0263083 |
| COL5A1 | collagen, type V, alpha 1 | 0.0262243 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0256883 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0249623 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0247291 |
| RAD51B | RAD51 paralog B | 0.0245 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0244523 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0244221 |
| NAV1 | neuron navigator 1 | 0.0244083 |
| CCND1 | cyclin D1 | 0.0241124 |
| PRELID2 | PRELI domain containing 2 | 0.0240399 |
| RNF213 | ring finger protein 213 | 0.0240189 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0240168 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0239376 |
| CAVIN1 | caveolae associated protein 1 | 0.0237596 |
| ZNF432 | zinc finger protein 432 | 0.0235104 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0234629 |
| PLEC | plectin | 0.0234504 |
| ANXA2 | annexin A2 | 0.0232957 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0232757 |
| PKM | pyruvate kinase, muscle | 0.0231383 |
| TMSB4X | thymosin beta 4, X-linked | 0.0231027 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0229044 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0228375 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0218026 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0217851 |
| KRT7 | keratin 7, type II | 0.0217196 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0216992 |
| TPM3 | tropomyosin 3 | 0.0214768 |
| FLNA | filamin A, alpha | 0.0211126 |
| TLE4 | transducin-like enhancer of split 4 | 0.0208668 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0207346 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.020691 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0206908 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0206252 |
| CALD1 | caldesmon 1 | 0.0206072 |
| TENM3 | teneurin transmembrane protein 3 | 0.0205442 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0202749 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0201918 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0200782 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0200134 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0199008 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0195854 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0194232 |
| CLIC4 | chloride intracellular channel 4 | 0.0193207 |
| FHIT | fragile histidine triad | 0.0192016 |
| SEPTIN9 | septin 9 | 0.0191346 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0188637 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0187013 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0186179 |
| FOXP1 | forkhead box P1 | 0.0186141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0647738 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0547833 |
| FTL | ferritin, light polypeptide | -0.0503647 |
| ATP13A3 | ATPase type 13A3 | -0.0316198 |
| NUP58 | nucleoporin 58 | -0.0294627 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0290187 |
| GOLGA4 | golgin A4 | -0.0285733 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0284685 |
| NDRG1 | N-myc downstream regulated 1 | -0.023611 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0219195 |
| CCNL1 | cyclin L1 | -0.0204965 |
| ARF4 | ADP-ribosylation factor 4 | -0.0204377 |
| PLIN2 | perilipin 2 | -0.0198896 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0194442 |
| SRP54 | signal recognition particle 54kDa | -0.0188448 |
| SUCO | SUN domain containing ossification factor | -0.0176636 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0176067 |
| ADM | adrenomedullin | -0.0175869 |
| TFG | TRK-fused gene | -0.0170063 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0167684 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0166257 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0161361 |
| SPAG9 | sperm associated antigen 9 | -0.0160868 |
| USP3 | ubiquitin specific peptidase 3 | -0.0155017 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0154586 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0152301 |
| NOP58 | NOP58 ribonucleoprotein | -0.0149979 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0147005 |
| RLF | rearranged L-myc fusion | -0.0146658 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0143553 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.014157 |
| ZNF292 | zinc finger protein 292 | -0.0137453 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0136846 |
| DENND4C | DENN/MADD domain containing 4C | -0.0134733 |
| TPD52 | tumor protein D52 | -0.013394 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0124838 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0122751 |
| SEC24A | SEC24 family member A | -0.0122147 |
| WDR45B | WD repeat domain 45B | -0.0122126 |
| RYBP | RING1 and YY1 binding protein | -0.0118847 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0117702 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0115039 |
| ARRDC3 | arrestin domain containing 3 | -0.0112497 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0111957 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0111614 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0110919 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0109537 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.010947 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.010841 |
| QKI | QKI, KH domain containing, RNA binding | -0.0106995 |
| RAB18 | RAB18, member RAS oncogene family | -0.0106865 |
| ANKRD10 | ankyrin repeat domain 10 | -0.010547 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.010397 |
| RIOK3 | RIO kinase 3 | -0.0103279 |
| MLF1 | myeloid leukemia factor 1 | -0.0101046 |
| NUP153 | nucleoporin 153kDa | -0.0100296 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0100114 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00999303 |
| LOX | lysyl oxidase | -0.00999111 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00982216 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00972444 |
| RAB8B | RAB8B, member RAS oncogene family | -0.00962811 |
| INSIG2 | insulin induced gene 2 | -0.00961992 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0095747 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.00939079 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.00932426 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | -0.00904117 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.00903978 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00898288 |
| TRAM1 | translocation associated membrane protein 1 | -0.00897421 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.00892228 |
| TBC1D23 | TBC1 domain family, member 23 | -0.00878011 |
| CTSD | cathepsin D | -0.00876125 |
| TMEM41B | transmembrane protein 41B | -0.00872978 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.00871979 |
| ANXA1 | annexin A1 | -0.00871904 |
| JUN | jun proto-oncogene | -0.00869883 |
| HELZ | helicase with zinc finger | -0.00868647 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00867369 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00867178 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0086572 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.00864902 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.00847634 |
| WTAP | Wilms tumor 1 associated protein | -0.00839476 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00838085 |
| TGFB2 | transforming growth factor, beta 2 | -0.00832828 |
| FOSL1 | FOS-like antigen 1 | -0.00830272 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.00829167 |
| COG5 | component of oligomeric golgi complex 5 | -0.00827818 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.00825224 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | -0.00821758 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.00815786 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00813777 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.00812979 |
| WAC | WW domain containing adaptor with coiled-coil | -0.00808461 |
| PLK2 | polo-like kinase 2 | -0.00807039 |
| RNF145 | ring finger protein 145 | -0.00796106 |
| OLA1 | Obg-like ATPase 1 | -0.00794768 |
| ECT2 | epithelial cell transforming 2 | -0.00786749 |
| COG6 | component of oligomeric golgi complex 6 | -0.0078625 |
