| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.100072 |
| FTL | ferritin, light polypeptide | 0.0801573 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0771364 |
| AHNAK | AHNAK nucleoprotein | 0.073287 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0714948 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0654787 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0629648 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0612291 |
| PTMA | prothymosin, alpha | 0.0606689 |
| ASPH | aspartate beta-hydroxylase | 0.0602865 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0578796 |
| APP | amyloid beta (A4) precursor protein | 0.056481 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0543892 |
| RPL23 | ribosomal protein L23 | 0.0538282 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0534131 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0524467 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0507959 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0497912 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0471165 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0461583 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0434252 |
| ACTG1 | actin gamma 1 | 0.0431063 |
| PLEC | plectin | 0.0419579 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0413049 |
| RPS3 | ribosomal protein S3 | 0.0397507 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0396754 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.039187 |
| RPS24 | ribosomal protein S24 | 0.039001 |
| TMSB10 | thymosin beta 10 | 0.0388245 |
| YBX3 | Y box binding protein 3 | 0.037999 |
| RPL12 | ribosomal protein L12 | 0.0376791 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0365149 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0357349 |
| CORO1C | coronin, actin binding protein, 1C | 0.0346278 |
| RTN4 | reticulon 4 | 0.0335931 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0334627 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0331384 |
| RPL11 | ribosomal protein L11 | 0.0328016 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0325953 |
| CDK17 | cyclin-dependent kinase 17 | 0.0318172 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0316649 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0316362 |
| MT2A | metallothionein 2A | 0.030955 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0307344 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0304373 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0303695 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0301825 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0298819 |
| RPL19 | ribosomal protein L19 | 0.0297273 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.029427 |
| RPL26 | ribosomal protein L26 | 0.0288289 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0288022 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0284812 |
| OGA | O-GlcNAcase | 0.0282251 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0281058 |
| RPLP0 | ribosomal protein, large, P0 | 0.027951 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0274255 |
| CAVIN1 | caveolae associated protein 1 | 0.027184 |
| RPS27A | ribosomal protein S27a | 0.0271497 |
| RPL4 | ribosomal protein L4 | 0.0271438 |
| TXNRD1 | thioredoxin reductase 1 | 0.0267855 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0266391 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.026636 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0265741 |
| RPS8 | ribosomal protein S8 | 0.0264864 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0261684 |
| RPL6 | ribosomal protein L6 | 0.0261494 |
| CTTN | cortactin | 0.0260054 |
| MATR3 | matrin 3 | 0.0257587 |
| RPL35 | ribosomal protein L35 | 0.025412 |
| RPS6 | ribosomal protein S6 | 0.0251066 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0249273 |
| RPL32 | ribosomal protein L32 | 0.0248712 |
| TPI1 | triosephosphate isomerase 1 | 0.0246529 |
| STC1 | stanniocalcin 1 | 0.0245307 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0244611 |
| SP100 | SP100 nuclear antigen | 0.0244164 |
| AEBP2 | AE binding protein 2 | 0.0244038 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0243598 |
| RPL34 | ribosomal protein L34 | 0.0243162 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0242849 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0241098 |
| TEX10 | testis expressed 10 | 0.0240345 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0239283 |
| RLF | rearranged L-myc fusion | 0.0239145 |
| MSN | moesin | 0.0236666 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0235467 |
| H1-0 | H1.0 linker histone | 0.0234658 |
| RPS13 | ribosomal protein S13 | 0.0234306 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0233344 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0230584 |
| RPLP2 | ribosomal protein, large, P2 | 0.0229537 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0229187 |
| PGK1 | phosphoglycerate kinase 1 | 0.0227079 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0227076 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0224473 |
| KISS1 | KiSS-1 metastasis-suppressor | 0.0223643 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0222952 |
| RPLP1 | ribosomal protein, large, P1 | 0.0219947 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0218749 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | -0.207077 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.117158 |
| MMP12 | matrix metallopeptidase 12 | -0.11233 |
| GPC6 | glypican 6 | -0.0918169 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0874896 |
| NDRG1 | N-myc downstream regulated 1 | -0.0813689 |
| DTNA | dystrobrevin, alpha | -0.0799451 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.079491 |
| EGR1 | early growth response 1 | -0.0763709 |
| LSAMP | limbic system-associated membrane protein | -0.0714461 |
| RUNX1 | runt-related transcription factor 1 | -0.0663607 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0583879 |
| CD109 | CD109 molecule | -0.05726 |
| VIM | vimentin | -0.0551107 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.055016 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0546966 |
| NAV1 | neuron navigator 1 | -0.0540599 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0497915 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0452038 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0433386 |
| CDH13 | cadherin 13 | -0.0425052 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0424543 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0424521 |
| POTEF | POTE ankyrin domain family, member F | -0.0410996 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0403952 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0391509 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0378701 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0365881 |
| NLGN1 | neuroligin 1 | -0.0332911 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0326078 |
| MCL1 | myeloid cell leukemia 1 | -0.0324591 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0309003 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0302833 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0288253 |
| FN1 | fibronectin 1 | -0.0282019 |
| PRKCE | protein kinase C, epsilon | -0.0281293 |
| SMAD3 | SMAD family member 3 | -0.0280627 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0275182 |
| PTK2 | protein tyrosine kinase 2 | -0.0273649 |
| TENM2 | teneurin transmembrane protein 2 | -0.0261256 |
| KIAA1549L | KIAA1549-like | -0.0259874 |
| JUN | jun proto-oncogene | -0.0259645 |
| FOXP1 | forkhead box P1 | -0.0258919 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0253342 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0251255 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0249533 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.024709 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0245764 |
| FNDC3B | fibronectin type III domain containing 3B | -0.024178 |
| RAD51B | RAD51 paralog B | -0.0237181 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.023632 |
| SBF2 | SET binding factor 2 | -0.0236059 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0225985 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.022503 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.022462 |
| HMGA1 | high mobility group AT-hook 1 | -0.0223143 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0221972 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0218008 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0216728 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.021317 |
| KDM2B | lysine (K)-specific demethylase 2B | -0.0211007 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.020886 |
| CD44 | CD44 molecule (Indian blood group) | -0.0208279 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0203441 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0199679 |
| EGFR | epidermal growth factor receptor | -0.0198483 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0197746 |
| ATXN1 | ataxin 1 | -0.0196842 |
| MSR1 | macrophage scavenger receptor 1 | -0.0196705 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0195027 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0192245 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0187645 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0184459 |
| MYADM | myeloid-associated differentiation marker | -0.018256 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0181907 |
| CUX1 | cut-like homeobox 1 | -0.0181771 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0179592 |
| BNC2 | basonuclin 2 | -0.0179588 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0179413 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.01784 |
| DIAPH2 | diaphanous-related formin 2 | -0.0176114 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0173533 |
| RAI14 | retinoic acid induced 14 | -0.017255 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0172378 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0171281 |
| DNER | delta/notch-like EGF repeat containing | -0.0169284 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.016862 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.016853 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0167599 |
| PCBP2 | poly(rC) binding protein 2 | -0.0167265 |
| SMYD3 | SET and MYND domain containing 3 | -0.0165694 |
| DIAPH3 | diaphanous-related formin 3 | -0.0163603 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0163526 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0158718 |
| ANO6 | anoctamin 6 | -0.0158692 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.015674 |
| FOSL1 | FOS-like antigen 1 | -0.015529 |
| PTEN | phosphatase and tensin homolog | -0.0154933 |
| PRELID2 | PRELI domain containing 2 | -0.0154844 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0154617 |
