| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.151159 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.140122 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.138932 |
| EZR | ezrin | 0.138915 |
| TXNIP | thioredoxin interacting protein | 0.137573 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.136365 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.129639 |
| FAT1 | FAT atypical cadherin 1 | 0.126766 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.111261 |
| VCL | vinculin | 0.101573 |
| AHNAK | AHNAK nucleoprotein | 0.0980132 |
| DSPP | dentin sialophosphoprotein | 0.0946232 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0907902 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0874109 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0836928 |
| MYO1E | myosin IE | 0.0831811 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0791291 |
| NDRG1 | N-myc downstream regulated 1 | 0.0722975 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0698963 |
| TPM4 | tropomyosin 4 | 0.0688335 |
| JUN | jun proto-oncogene | 0.0661088 |
| LMO7 | LIM domain 7 | 0.0636147 |
| PIGR | polymeric immunoglobulin receptor | 0.0627497 |
| ACTN4 | actinin, alpha 4 | 0.0593739 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0585315 |
| VEGFA | vascular endothelial growth factor A | 0.0584528 |
| MUC13 | mucin 13, cell surface associated | 0.0580787 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0550081 |
| KLF6 | Kruppel-like factor 6 | 0.0547883 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0545944 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0524157 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0523822 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0511241 |
| H1-0 | H1.0 linker histone | 0.0504634 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0490829 |
| FLNB | filamin B, beta | 0.0474877 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0466214 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0461735 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0457099 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0442331 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0439682 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0430477 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0426477 |
| PGK1 | phosphoglycerate kinase 1 | 0.0426151 |
| KRT8 | keratin 8, type II | 0.042482 |
| ANXA2 | annexin A2 | 0.0423092 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0419569 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0415197 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0414624 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0413402 |
| PLEC | plectin | 0.0403162 |
| KRT18 | keratin 18, type I | 0.0397554 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0393575 |
| EMP1 | epithelial membrane protein 1 | 0.0391241 |
| ANXA1 | annexin A1 | 0.0384452 |
| MYO5B | myosin VB | 0.0381846 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0374019 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0366564 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0365065 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0356838 |
| EPHA2 | EPH receptor A2 | 0.0355104 |
| PALLD | palladin, cytoskeletal associated protein | 0.0349364 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0349113 |
| FHIT | fragile histidine triad | 0.0348756 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0347672 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0344694 |
| FHL2 | four and a half LIM domains 2 | 0.033662 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0325777 |
| SMYD3 | SET and MYND domain containing 3 | 0.0324858 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0324156 |
| ITGA6 | integrin, alpha 6 | 0.032313 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0322208 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0321369 |
| EGR1 | early growth response 1 | 0.0321115 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0314742 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0314646 |
| RPLP0 | ribosomal protein, large, P0 | 0.0312517 |
| AREG | amphiregulin | 0.0309722 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0308757 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0304528 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0302496 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0300653 |
| TPM1 | tropomyosin 1 (alpha) | 0.0300292 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0297094 |
| FAM13A | family with sequence similarity 13, member A | 0.0292195 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.028772 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0287207 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0285162 |
| CUX1 | cut-like homeobox 1 | 0.0284849 |
| USP53 | ubiquitin specific peptidase 53 | 0.0284481 |
| MYO1D | myosin ID | 0.0283002 |
| LMNA | lamin A/C | 0.0276486 |
| SNX9 | sorting nexin 9 | 0.0275994 |
| S100A6 | S100 calcium binding protein A6 | 0.0275994 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0275588 |
| EPCAM | epithelial cell adhesion molecule | 0.0274745 |
| PCDH9 | protocadherin 9 | 0.0274687 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0274186 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0273266 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0271634 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.115442 |
| RPS12 | ribosomal protein S12 | -0.0872877 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0776405 |
| RPL37A | ribosomal protein L37a | -0.0763419 |
| GOLGA4 | golgin A4 | -0.0637656 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0531027 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0524526 |
| RPS8 | ribosomal protein S8 | -0.0512637 |
| RPS23 | ribosomal protein S23 | -0.0508311 |
| RPS3 | ribosomal protein S3 | -0.0470453 |
| RPLP2 | ribosomal protein, large, P2 | -0.0470022 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.046883 |
| COG5 | component of oligomeric golgi complex 5 | -0.0461772 |
| RPS29 | ribosomal protein S29 | -0.0455784 |
| RPL13A | ribosomal protein L13a | -0.045075 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.041948 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0387499 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.038515 |
| RBM25 | RNA binding motif protein 25 | -0.0370019 |
| PTEN | phosphatase and tensin homolog | -0.0365201 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0363121 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0349586 |
| GPHN | gephyrin | -0.0346019 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0342799 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0340403 |
| RPLP1 | ribosomal protein, large, P1 | -0.0337768 |
| RPL26 | ribosomal protein L26 | -0.0333757 |
| SCFD1 | sec1 family domain containing 1 | -0.0331168 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0318744 |
| RPL28 | ribosomal protein L28 | -0.0315259 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0310057 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0309127 |
| RPS27A | ribosomal protein S27a | -0.0302562 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0294955 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0287139 |
| RPL9 | ribosomal protein L9 | -0.0286306 |
| RPL38 | ribosomal protein L38 | -0.027748 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0277151 |
| METTL15 | methyltransferase like 15 | -0.0274912 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0274843 |
| RPL31 | ribosomal protein L31 | -0.0274522 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0270065 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0268739 |
| MT2A | metallothionein 2A | -0.0267028 |
| RPL37 | ribosomal protein L37 | -0.026569 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0265288 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0258686 |
| PGM3 | phosphoglucomutase 3 | -0.0252005 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0250714 |
| NBAS | neuroblastoma amplified sequence | -0.0250314 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0249649 |
| RPS6 | ribosomal protein S6 | -0.0248147 |
| RPS17 | ribosomal protein S17 | -0.0248003 |
| RPS2 | ribosomal protein S2 | -0.0242114 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0240731 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0238915 |
| RPL35 | ribosomal protein L35 | -0.0236199 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | -0.0235884 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0232472 |
| NPSR1 | neuropeptide S receptor 1 | -0.023188 |
| GOLGB1 | golgin B1 | -0.0231538 |
| RNF145 | ring finger protein 145 | -0.0227033 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0223657 |
| POTEF | POTE ankyrin domain family, member F | -0.0221685 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0220878 |
| OGA | O-GlcNAcase | -0.0219235 |
| ACTG1 | actin gamma 1 | -0.0219015 |
| RPS24 | ribosomal protein S24 | -0.0217961 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | -0.0216875 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0213849 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0213679 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0212204 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.021176 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0209547 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0209097 |
| SRP54 | signal recognition particle 54kDa | -0.0207981 |
| CDK13 | cyclin-dependent kinase 13 | -0.0205509 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0204267 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0204258 |
| USO1 | USO1 vesicle transport factor | -0.0203076 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0202842 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0202089 |
| SEC24D | SEC24 family member D | -0.0201865 |
| S100P | S100 calcium binding protein P | -0.0201018 |
| NEBL | nebulette | -0.0200004 |
| RPS5 | ribosomal protein S5 | -0.0199761 |
| COG6 | component of oligomeric golgi complex 6 | -0.0198333 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0197692 |
| PNN | pinin, desmosome associated protein | -0.0197222 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0196235 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0196049 |
| RFX7 | regulatory factor X, 7 | -0.0195793 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.019567 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.019311 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0191889 |
| DYM | dymeclin | -0.0189487 |
| AGRN | agrin | -0.0187985 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0187377 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0187014 |
| SLC10A7 | solute carrier family 10, member 7 | -0.0185452 |
