| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSCAM | Down syndrome cell adhesion molecule | 0.112815 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.112726 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0838388 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0725765 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0723652 |
| LAMC2 | laminin, gamma 2 | 0.0692351 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0603724 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0567626 |
| FAM13A | family with sequence similarity 13, member A | 0.0538852 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0499603 |
| LMO7 | LIM domain 7 | 0.0493793 |
| MYO5B | myosin VB | 0.0467758 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0467397 |
| ABHD17C | abhydrolase domain containing 17C | 0.0445203 |
| LAMB3 | laminin, beta 3 | 0.0441298 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0434287 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0407377 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0406317 |
| TJP1 | tight junction protein 1 | 0.040256 |
| MCL1 | myeloid cell leukemia 1 | 0.0401067 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0397359 |
| EGFR | epidermal growth factor receptor | 0.0396041 |
| RNF145 | ring finger protein 145 | 0.0393145 |
| NPTN | neuroplastin | 0.0381675 |
| KYNU | kynureninase | 0.0375584 |
| VEGFA | vascular endothelial growth factor A | 0.0372895 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0370977 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0367504 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0355618 |
| NUMB | numb homolog (Drosophila) | 0.0354544 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0346995 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0345986 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0343008 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0342546 |
| LAMA4 | laminin, alpha 4 | 0.0341641 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0340423 |
| LDLR | low density lipoprotein receptor | 0.0334637 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0332297 |
| MYO1E | myosin IE | 0.0331584 |
| VCL | vinculin | 0.0328016 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0326584 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0326291 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0319029 |
| MLPH | melanophilin | 0.0318874 |
| SCEL | sciellin | 0.0318348 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0317993 |
| ATM | ATM serine/threonine kinase | 0.0316674 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0311117 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0310534 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0309934 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0308439 |
| INTS6 | integrator complex subunit 6 | 0.0302876 |
| H3-3B | H3.3 histone B | 0.0302634 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0299899 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0298674 |
| MYO10 | myosin X | 0.0296113 |
| NABP1 | nucleic acid binding protein 1 | 0.0293653 |
| ATOSA | atos homolog A | 0.0286466 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0285415 |
| ZNF292 | zinc finger protein 292 | 0.0285057 |
| KIF13B | kinesin family member 13B | 0.0281735 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0280783 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0280554 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0276293 |
| ABI1 | abl-interactor 1 | 0.027585 |
| FAT1 | FAT atypical cadherin 1 | 0.0274757 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0274703 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0268269 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0267747 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0267547 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0266443 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0265677 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0262684 |
| ACTN1 | actinin, alpha 1 | 0.02619 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0260985 |
| CREBBP | CREB binding protein | 0.0259494 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.02582 |
| USP24 | ubiquitin specific peptidase 24 | 0.0257787 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.0256794 |
| INHBA | inhibin, beta A | 0.0253953 |
| XPO1 | exportin 1 | 0.0248866 |
| JAK1 | Janus kinase 1 | 0.0247568 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0247556 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0246482 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0245531 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0245012 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0243651 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0243242 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0242343 |
| EHF | ets homologous factor | 0.0242162 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0240253 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0238504 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0237075 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0235869 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0235069 |
| IL1RN | interleukin 1 receptor antagonist | 0.0234529 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0229727 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0229296 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0228927 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0228782 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174665 |
| IGF2 | insulin-like growth factor 2 | -0.16028 |
| MT2A | metallothionein 2A | -0.142566 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.12964 |
| FTL | ferritin, light polypeptide | -0.12758 |
| VIM | vimentin | -0.113815 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.10469 |
| FLNB | filamin B, beta | -0.0757655 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.075763 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0749167 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0697794 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.067581 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0657859 |
| RPS16 | ribosomal protein S16 | -0.0636815 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0616825 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0577275 |
| LOXL2 | lysyl oxidase-like 2 | -0.0573988 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0552823 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0523051 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0523043 |
| TMSB10 | thymosin beta 10 | -0.0518715 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.050352 |
| POTEF | POTE ankyrin domain family, member F | -0.0490933 |
| NDRG1 | N-myc downstream regulated 1 | -0.0490662 |
| ACTG1 | actin gamma 1 | -0.0488729 |
| RPL11 | ribosomal protein L11 | -0.0475464 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0469616 |
| RNF213 | ring finger protein 213 | -0.0463692 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0462056 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0433667 |
| RPS19 | ribosomal protein S19 | -0.0411658 |
| GPC6 | glypican 6 | -0.0403932 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0387895 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0384724 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0381321 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0381241 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0379956 |
| RPLP1 | ribosomal protein, large, P1 | -0.0379928 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0376301 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0370867 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0363043 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0362775 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0361599 |
| FN1 | fibronectin 1 | -0.0357996 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0354718 |
| S100A6 | S100 calcium binding protein A6 | -0.0349141 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0345967 |
| CCND1 | cyclin D1 | -0.0336237 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.032998 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0326061 |
| PDE10A | phosphodiesterase 10A | -0.0325592 |
| RACK1 | receptor for activated C kinase 1 | -0.0320284 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0317882 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0315864 |
| SBF2 | SET binding factor 2 | -0.0315215 |
| RPL31 | ribosomal protein L31 | -0.0312626 |
| SEPTIN2 | septin 2 | -0.0311388 |
| NF1 | neurofibromin 1 | -0.0309667 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0307758 |
| ERBIN | erbb2 interacting protein | -0.0306037 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0300546 |
| C3 | complement component 3 | -0.0298847 |
| CCDC88A | coiled-coil domain containing 88A | -0.0297503 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0294714 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0293614 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0292419 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0290221 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.028863 |
| RAB10 | RAB10, member RAS oncogene family | -0.0287894 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0284905 |
| SEPTIN7 | septin 7 | -0.0283688 |
| CDK17 | cyclin-dependent kinase 17 | -0.0281534 |
| RPL37A | ribosomal protein L37a | -0.0279253 |
| RPL38 | ribosomal protein L38 | -0.0277246 |
| FBXO11 | F-box protein 11 | -0.0274091 |
| DIAPH3 | diaphanous-related formin 3 | -0.027297 |
| RPL37 | ribosomal protein L37 | -0.0272869 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0272728 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0272357 |
| RPS29 | ribosomal protein S29 | -0.0267616 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0267194 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0266125 |
| LMNA | lamin A/C | -0.0263224 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0258798 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0258275 |
| GOLGA4 | golgin A4 | -0.0257051 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.025325 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0253109 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0252661 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0251035 |
| OLA1 | Obg-like ATPase 1 | -0.0250582 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0250017 |
| MTDH | metadherin | -0.0249599 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0247635 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0236939 |
| SMYD3 | SET and MYND domain containing 3 | -0.0232445 |
| TPI1 | triosephosphate isomerase 1 | -0.0228981 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0227961 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0225854 |
| ECE1 | endothelin converting enzyme 1 | -0.0225384 |
