| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.325553 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.148087 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.11884 |
| YBX3 | Y box binding protein 3 | 0.112691 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.111302 |
| TPM3 | tropomyosin 3 | 0.0953005 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0742542 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.073053 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0712365 |
| GRAMD1B | GRAM domain containing 1B | 0.0655628 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0608876 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.056704 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.052683 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0517482 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0516649 |
| SET | SET nuclear proto-oncogene | 0.0510488 |
| BRD2 | bromodomain containing 2 | 0.0509931 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0506033 |
| RPL3 | ribosomal protein L3 | 0.0497468 |
| RPS3 | ribosomal protein S3 | 0.0495054 |
| KRT18 | keratin 18, type I | 0.0492303 |
| TPI1 | triosephosphate isomerase 1 | 0.0490873 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0487432 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0485207 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0485136 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0478923 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.046425 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0447261 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0442499 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0426985 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0407051 |
| CTTN | cortactin | 0.0401087 |
| MKI67 | marker of proliferation Ki-67 | 0.0395691 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0393492 |
| RPS2 | ribosomal protein S2 | 0.0385413 |
| ANO6 | anoctamin 6 | 0.0379285 |
| CLTC | clathrin, heavy chain (Hc) | 0.0378758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.037402 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0372705 |
| PTMA | prothymosin, alpha | 0.0370895 |
| MSN | moesin | 0.0360283 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0353771 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0351657 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0350009 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0346701 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.033696 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0320377 |
| ACTN1 | actinin, alpha 1 | 0.0318074 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0317137 |
| CPNE1 | copine I | 0.0312151 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0311107 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0309108 |
| PNN | pinin, desmosome associated protein | 0.0305963 |
| STK4 | serine/threonine kinase 4 | 0.0302129 |
| NONO | non-POU domain containing, octamer-binding | 0.0295776 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0294509 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292866 |
| PLEC | plectin | 0.0288812 |
| RRM2 | ribonucleotide reductase M2 | 0.0288611 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0286511 |
| TPM2 | tropomyosin 2 (beta) | 0.028529 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0284707 |
| DSPP | dentin sialophosphoprotein | 0.0278671 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0277778 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0269066 |
| RTN4 | reticulon 4 | 0.0268388 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0265624 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0259905 |
| DENR | density-regulated protein | 0.0257986 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0257975 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0254934 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0249068 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0247322 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0245589 |
| CEP250 | centrosomal protein 250kDa | 0.024288 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0240625 |
| YBX1 | Y box binding protein 1 | 0.0236082 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0235433 |
| RPS12 | ribosomal protein S12 | 0.0233932 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0230698 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0229561 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0228229 |
| ADAR | adenosine deaminase, RNA-specific | 0.0226553 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0226319 |
| SPAG9 | sperm associated antigen 9 | 0.0226168 |
| TLN1 | talin 1 | 0.0223575 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0223065 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0219144 |
| MSH6 | mutS homolog 6 | 0.0218929 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0216721 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0215344 |
| TXNRD1 | thioredoxin reductase 1 | 0.0215288 |
| XPO1 | exportin 1 | 0.0215283 |
| CAPRIN2 | caprin family member 2 | 0.0214829 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0214185 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.021401 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0212433 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0211396 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0209471 |
| CALD1 | caldesmon 1 | 0.0207173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0682758 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.068159 |
| RPL35A | ribosomal protein L35a | -0.0645189 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0418237 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0400468 |
| RAD51B | RAD51 paralog B | -0.0388005 |
| VIM | vimentin | -0.0369185 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0364115 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0355046 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.035218 |
| OSMR | oncostatin M receptor | -0.0323487 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0290185 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0271781 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0271626 |
| HMGA2 | high mobility group AT-hook 2 | -0.0267817 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0266675 |
| TMEM165 | transmembrane protein 165 | -0.0252922 |
| GNAS | GNAS complex locus | -0.023908 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0237951 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0236655 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0224372 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0212031 |
| RPS24 | ribosomal protein S24 | -0.0211484 |
| EGFR | epidermal growth factor receptor | -0.0210581 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0210415 |
| PDE10A | phosphodiesterase 10A | -0.0202256 |
| SMAD3 | SMAD family member 3 | -0.0200438 |
| ATG7 | autophagy related 7 | -0.019614 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0191361 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0187161 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0182403 |
| KPNB1 | karyopherin (importin) beta 1 | -0.017757 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0175377 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0173431 |
| RPL34 | ribosomal protein L34 | -0.0172138 |
| ATXN1 | ataxin 1 | -0.0167644 |
| RYR3 | ryanodine receptor 3 | -0.0167468 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0162478 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0160883 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0159778 |
| HMGA1 | high mobility group AT-hook 1 | -0.0159112 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0157958 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0152205 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0152106 |
| RSF1 | remodeling and spacing factor 1 | -0.0148578 |
| TMSB10 | thymosin beta 10 | -0.0146384 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.014482 |
| DENND1A | DENN/MADD domain containing 1A | -0.0143175 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0142772 |
| AHNAK | AHNAK nucleoprotein | -0.0142406 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0141798 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0141778 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0141447 |
| ENOSF1 | enolase superfamily member 1 | -0.0140456 |
| WASF2 | WAS protein family, member 2 | -0.0139143 |
| CCND1 | cyclin D1 | -0.0138567 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0137809 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0137107 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0134947 |
| TMEM131 | transmembrane protein 131 | -0.0134745 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0134274 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0133827 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0133392 |
| TAPBP | TAP binding protein (tapasin) | -0.01323 |
| ATF6 | activating transcription factor 6 | -0.0132207 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0131742 |
| NF1 | neurofibromin 1 | -0.0130325 |
| KIAA1328 | KIAA1328 | -0.0130144 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0129767 |
| FTL | ferritin, light polypeptide | -0.0128805 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0128219 |
| VCL | vinculin | -0.0128173 |
| RPS4X | ribosomal protein S4, X-linked | -0.0125826 |
| RPS20 | ribosomal protein S20 | -0.0125333 |
| RPL23 | ribosomal protein L23 | -0.0120787 |
| SBF2 | SET binding factor 2 | -0.0120425 |
| KLF6 | Kruppel-like factor 6 | -0.0120251 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.012014 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0119766 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0119734 |
| RPL13A | ribosomal protein L13a | -0.0119733 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0118862 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0118771 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.011837 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0118216 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0117999 |
| GLG1 | golgi glycoprotein 1 | -0.0117847 |
| RPLP0 | ribosomal protein, large, P0 | -0.0117616 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0117038 |
| ZFP64 | ZFP64 zinc finger protein | -0.0116778 |
| HM13 | histocompatibility (minor) 13 | -0.0116497 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0116212 |
| MAP4 | microtubule-associated protein 4 | -0.0115282 |
| PHF14 | PHD finger protein 14 | -0.0114094 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0114002 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0113742 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0112678 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.0112299 |
| FMN1 | formin 1 | -0.0110669 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0110656 |
