| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Minodronic acid_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0790074 |
| TXNRD1 | thioredoxin reductase 1 | 0.0585923 |
| GRAMD1B | GRAM domain containing 1B | 0.0563835 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0555968 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0538624 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0528748 |
| ASPH | aspartate beta-hydroxylase | 0.0510503 |
| MYOF | myoferlin | 0.0506583 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0483872 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.04759 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0463692 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0440631 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0404059 |
| UBC | ubiquitin C | 0.037832 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.037518 |
| GDA | guanine deaminase | 0.0373222 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0348467 |
| KYNU | kynureninase | 0.0344561 |
| FLNB | filamin B, beta | 0.0327117 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.032088 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0316535 |
| FN1 | fibronectin 1 | 0.0313344 |
| NEK7 | NIMA-related kinase 7 | 0.0312987 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0311724 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0307063 |
| DST | dystonin | 0.030531 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0301897 |
| RPL3 | ribosomal protein L3 | 0.0299821 |
| PDLIM5 | PDZ and LIM domain 5 | 0.029959 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.028713 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0285664 |
| TPM3 | tropomyosin 3 | 0.0274499 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.027259 |
| COL5A2 | collagen, type V, alpha 2 | 0.027113 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.026921 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0266706 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0251539 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0248382 |
| PDE10A | phosphodiesterase 10A | 0.0246908 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.024585 |
| MSN | moesin | 0.0244667 |
| EZR | ezrin | 0.0243086 |
| PCBP2 | poly(rC) binding protein 2 | 0.0237622 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0234012 |
| CD109 | CD109 molecule | 0.0228778 |
| NONO | non-POU domain containing, octamer-binding | 0.0227818 |
| SET | SET nuclear proto-oncogene | 0.0222942 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0218707 |
| CENPF | centromere protein F, 350/400kDa | 0.0216349 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0216044 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0212313 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0210306 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0209374 |
| LDHA | lactate dehydrogenase A | 0.0208435 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0207458 |
| TBXT | T-box transcription factor T | 0.0207279 |
| EFNA5 | ephrin-A5 | 0.0205236 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0203975 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0201718 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0201026 |
| RGS2 | regulator of G-protein signaling 2 | 0.0199859 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0199508 |
| ANXA1 | annexin A1 | 0.0196197 |
| ENO1 | enolase 1, (alpha) | 0.0194578 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0192398 |
| RTN4 | reticulon 4 | 0.0190801 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0190602 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0189948 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0183865 |
| SPAG9 | sperm associated antigen 9 | 0.0180497 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0180289 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0175007 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0173957 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0172268 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0168593 |
| FLNA | filamin A, alpha | 0.0164199 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0163806 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0163781 |
| COL4A6 | collagen, type IV, alpha 6 | 0.016119 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0159567 |
| LAMA1 | laminin, alpha 1 | 0.0158376 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.015696 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0155988 |
| RAB3B | RAB3B, member RAS oncogene family | 0.015535 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0154493 |
| ATP13A3 | ATPase type 13A3 | 0.0152903 |
| AHNAK | AHNAK nucleoprotein | 0.0152249 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0152197 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0150791 |
| NBAS | neuroblastoma amplified sequence | 0.015064 |
| APP | amyloid beta (A4) precursor protein | 0.0147052 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0146464 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0145927 |
| MKI67 | marker of proliferation Ki-67 | 0.0145397 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0144187 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0142668 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0142043 |
| TNPO1 | transportin 1 | 0.0142041 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0140723 |
| PTEN | phosphatase and tensin homolog | 0.014011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.128614 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.121388 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0786704 |
| RPL35A | ribosomal protein L35a | -0.0773309 |
| VIM | vimentin | -0.0728472 |
| PTMA | prothymosin, alpha | -0.0656211 |
| RPS24 | ribosomal protein S24 | -0.0631355 |
| RPLP1 | ribosomal protein, large, P1 | -0.0608066 |
| RPL31 | ribosomal protein L31 | -0.0528758 |
| RPS6 | ribosomal protein S6 | -0.0521396 |
| RPL37A | ribosomal protein L37a | -0.0479251 |
| HLA-B | major histocompatibility complex, class I, B | -0.0463505 |
| RPS8 | ribosomal protein S8 | -0.0455989 |
| RPS19 | ribosomal protein S19 | -0.0425029 |
| RPL34 | ribosomal protein L34 | -0.0418205 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0389849 |
| RPS29 | ribosomal protein S29 | -0.0381155 |
| RPL9 | ribosomal protein L9 | -0.0373674 |
| CDH13 | cadherin 13 | -0.0367725 |
| RPS25 | ribosomal protein S25 | -0.0346204 |
| RPL36A | ribosomal protein L36a | -0.0343679 |
| RPL38 | ribosomal protein L38 | -0.0342439 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0341625 |
| RPS23 | ribosomal protein S23 | -0.0337283 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0323642 |
| RPL26 | ribosomal protein L26 | -0.0320963 |
| TMSB10 | thymosin beta 10 | -0.0320676 |
| RPS13 | ribosomal protein S13 | -0.0311413 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0299527 |
| RPL37 | ribosomal protein L37 | -0.0299297 |
| RPL12 | ribosomal protein L12 | -0.029229 |
| RPL11 | ribosomal protein L11 | -0.0291836 |
| RPLP2 | ribosomal protein, large, P2 | -0.0282539 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0281431 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0280669 |
| FTL | ferritin, light polypeptide | -0.0270224 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0268409 |
| RPS16 | ribosomal protein S16 | -0.0262975 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0257284 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0248478 |
| RPL36 | ribosomal protein L36 | -0.0246125 |
| RPS21 | ribosomal protein S21 | -0.0243615 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.023998 |
| STC1 | stanniocalcin 1 | -0.0228454 |
| RPL19 | ribosomal protein L19 | -0.0228316 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0225202 |
| RPS14 | ribosomal protein S14 | -0.0224715 |
| CTSL | cathepsin L | -0.0221954 |
| RPL7A | ribosomal protein L7a | -0.0220946 |
| RPLP0 | ribosomal protein, large, P0 | -0.0213143 |
| RPS12 | ribosomal protein S12 | -0.0207524 |
| NDRG1 | N-myc downstream regulated 1 | -0.0207081 |
| HLA-A | major histocompatibility complex, class I, A | -0.0206786 |
| VCL | vinculin | -0.0203769 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0199688 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0199128 |
| SMYD3 | SET and MYND domain containing 3 | -0.0197889 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0191696 |
| RPS11 | ribosomal protein S11 | -0.018946 |
| RPS20 | ribosomal protein S20 | -0.0184857 |
| CUX1 | cut-like homeobox 1 | -0.0183242 |
| AUTS2 | autism susceptibility candidate 2 | -0.0182277 |
| RPL13A | ribosomal protein L13a | -0.0176319 |
| RPS17 | ribosomal protein S17 | -0.0176222 |
| RPL27 | ribosomal protein L27 | -0.0173182 |
| GNAS | GNAS complex locus | -0.017268 |
| RPL23 | ribosomal protein L23 | -0.0172117 |
| ACTG1 | actin gamma 1 | -0.0171065 |
| RPS28 | ribosomal protein S28 | -0.0170812 |
| RPL27A | ribosomal protein L27a | -0.0169788 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0169669 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0168492 |
| B2M | beta-2-microglobulin | -0.0164441 |
| RPS10 | ribosomal protein S10 | -0.0161807 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0160495 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.015742 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0156075 |
| NCKAP5 | NCK-associated protein 5 | -0.015552 |
| SQSTM1 | sequestosome 1 | -0.0152743 |
| RPL28 | ribosomal protein L28 | -0.0150676 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0147396 |
| S100A6 | S100 calcium binding protein A6 | -0.0145711 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0145413 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0144226 |
| RPL32 | ribosomal protein L32 | -0.0143359 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0142587 |
| AEBP2 | AE binding protein 2 | -0.0141726 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0141296 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0138906 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.013596 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0135169 |
| RPS3 | ribosomal protein S3 | -0.0135072 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0134577 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0131747 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0131549 |
| S100A10 | S100 calcium binding protein A10 | -0.0129976 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.012997 |
| RAB31 | RAB31, member RAS oncogene family | -0.0128102 |
| RPL30 | ribosomal protein L30 | -0.0126968 |
| IER3 | immediate early response 3 | -0.0126088 |
