| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.0918234 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0859425 |
| EGR1 | early growth response 1 | 0.0358451 |
| FBL | fibrillarin | 0.0346352 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0343866 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0334169 |
| VIM | vimentin | 0.0283505 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0243459 |
| MCL1 | myeloid cell leukemia 1 | 0.022548 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0221812 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0205794 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0187896 |
| INTS6 | integrator complex subunit 6 | 0.0172318 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0166427 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0150866 |
| SFTPA2 | surfactant protein A2 | 0.0150411 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0147586 |
| TPM1 | tropomyosin 1 (alpha) | 0.0146304 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0144882 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0143809 |
| ANKRD11 | ankyrin repeat domain 11 | 0.013975 |
| MYO1E | myosin IE | 0.0136628 |
| MSN | moesin | 0.0134018 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0131224 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0128881 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0121582 |
| VEGFA | vascular endothelial growth factor A | 0.0121029 |
| SEPTIN9 | septin 9 | 0.0117965 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0117212 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0116293 |
| HMGA2 | high mobility group AT-hook 2 | 0.0115813 |
| DST | dystonin | 0.0111476 |
| PFN1 | profilin 1 | 0.0107484 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0106829 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0105591 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0105446 |
| ANGPTL4 | angiopoietin-like 4 | 0.010485 |
| NUP98 | nucleoporin 98kDa | 0.010466 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0101923 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.00988673 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.00950051 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00949316 |
| RSU1 | Ras suppressor protein 1 | 0.00942554 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00941231 |
| POTEF | POTE ankyrin domain family, member F | 0.00916241 |
| HDAC9 | histone deacetylase 9 | 0.00911608 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00891322 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.00880221 |
| PLEC | plectin | 0.008708 |
| TNRC18 | trinucleotide repeat containing 18 | 0.00868352 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00847562 |
| ACTG1 | actin gamma 1 | 0.00820662 |
| NHSL1 | NHS-like 1 | 0.00817992 |
| HMGA1 | high mobility group AT-hook 1 | 0.00815907 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00810371 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.00802045 |
| MYO10 | myosin X | 0.0080079 |
| ATG7 | autophagy related 7 | 0.00799383 |
| ACTN1 | actinin, alpha 1 | 0.00798865 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00797298 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00789901 |
| ZFP36 | ZFP36 ring finger protein | 0.00783599 |
| FTL | ferritin, light polypeptide | 0.00767304 |
| MAP1B | microtubule-associated protein 1B | 0.00762665 |
| CTSD | cathepsin D | 0.00757657 |
| JUN | jun proto-oncogene | 0.00749963 |
| CENPF | centromere protein F, 350/400kDa | 0.00747836 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00745854 |
| RNF220 | ring finger protein 220 | 0.00744083 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00736181 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.00733599 |
| MYADM | myeloid-associated differentiation marker | 0.00728123 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00712856 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.00709915 |
| FERMT2 | fermitin family member 2 | 0.00709682 |
| FBXO17 | F-box protein 17 | 0.00698423 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00685278 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.00684816 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.00669017 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0066512 |
| BRD2 | bromodomain containing 2 | 0.00660252 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00658987 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.00648717 |
| LMNA | lamin A/C | 0.00647135 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00635483 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.00634748 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.00633658 |
| PLAU | plasminogen activator, urokinase | 0.00619824 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.00618854 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00608143 |
| FOSL1 | FOS-like antigen 1 | 0.00606849 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0060415 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00603439 |
| UBAP2 | ubiquitin associated protein 2 | 0.0059493 |
| PKM | pyruvate kinase, muscle | 0.00593144 |
| RASAL2 | RAS protein activator like 2 | 0.00591783 |
| MED29 | mediator complex subunit 29 | 0.005831 |
| BRD4 | bromodomain containing 4 | 0.00580796 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00580117 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00576478 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0326337 |
| TXNRD1 | thioredoxin reductase 1 | -0.0240785 |
| ANXA2 | annexin A2 | -0.0229089 |
| SMAD3 | SMAD family member 3 | -0.0227512 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0206546 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0204883 |
| ZNF292 | zinc finger protein 292 | -0.0197187 |
| OGA | O-GlcNAcase | -0.016329 |
| CD44 | CD44 molecule (Indian blood group) | -0.0157131 |
| MYOF | myoferlin | -0.0153987 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.015144 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0148862 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.014338 |
| SPAG9 | sperm associated antigen 9 | -0.013007 |
| TMEM123 | transmembrane protein 123 | -0.0129729 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0126378 |
| RPS12 | ribosomal protein S12 | -0.011916 |
| CANX | calnexin | -0.0119006 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0118775 |
| RPLP2 | ribosomal protein, large, P2 | -0.0116042 |
| RPLP1 | ribosomal protein, large, P1 | -0.0109423 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0106787 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.0105411 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0104325 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0103593 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.010322 |
| ARRDC3 | arrestin domain containing 3 | -0.0102354 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0102272 |
| JMJD1C | jumonji domain containing 1C | -0.0102212 |
| RPL38 | ribosomal protein L38 | -0.0101436 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00997307 |
| PGK1 | phosphoglycerate kinase 1 | -0.00996476 |
| RPL37A | ribosomal protein L37a | -0.00989776 |
| TMEM41B | transmembrane protein 41B | -0.00987194 |
| FOXO3 | forkhead box O3 | -0.00975888 |
| RTN4 | reticulon 4 | -0.00971828 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.00960744 |
| PRELID2 | PRELI domain containing 2 | -0.00946737 |
| RPS16 | ribosomal protein S16 | -0.00945849 |
| SNX14 | sorting nexin 14 | -0.00938678 |
| MORF4L2 | mortality factor 4 like 2 | -0.0093701 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0092266 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00920528 |
| RLF | rearranged L-myc fusion | -0.00916741 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00906275 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00905361 |
| GOLGA4 | golgin A4 | -0.00904826 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00893321 |
| TNPO1 | transportin 1 | -0.00886167 |
| RUNX1 | runt-related transcription factor 1 | -0.00874555 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.00863369 |
| CALU | calumenin | -0.00842903 |
| S100A10 | S100 calcium binding protein A10 | -0.00840523 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.008361 |
| RBM39 | RNA binding motif protein 39 | -0.0082807 |
| RPL28 | ribosomal protein L28 | -0.00818946 |
| SUCO | SUN domain containing ossification factor | -0.00809844 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.00801724 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00795299 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00794744 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00781813 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00764985 |
| AFDN | afadin, adherens junction formation factor | -0.00748795 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00746071 |
| WDR45B | WD repeat domain 45B | -0.0073129 |
| SBF2 | SET binding factor 2 | -0.00728074 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00725768 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00717807 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.00705361 |
| USP3 | ubiquitin specific peptidase 3 | -0.00696513 |
| RPS27A | ribosomal protein S27a | -0.00693621 |
| CD109 | CD109 molecule | -0.0069323 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00690539 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00690535 |
| YEATS2 | YEATS domain containing 2 | -0.00684007 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0068246 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.00678851 |
| MATR3 | matrin 3 | -0.00678194 |
| HM13 | histocompatibility (minor) 13 | -0.00676467 |
| KLF6 | Kruppel-like factor 6 | -0.00671279 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.00669694 |
| RPS3 | ribosomal protein S3 | -0.00665177 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00663435 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0066157 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.00654994 |
| CAVIN1 | caveolae associated protein 1 | -0.0065461 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.00647181 |
| ANLN | anillin, actin binding protein | -0.00644478 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0063961 |
| SHTN1 | shootin 1 | -0.00636567 |
| ZFR | zinc finger RNA binding protein | -0.00629348 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00623751 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0062355 |
| COG5 | component of oligomeric golgi complex 5 | -0.00617366 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.00615138 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0061465 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.00614635 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.00613265 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00609639 |
| ATP13A3 | ATPase type 13A3 | -0.00609583 |
