| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.140578 |
| STC1 | stanniocalcin 1 | 0.127204 |
| HLA-B | major histocompatibility complex, class I, B | 0.110438 |
| ANGPTL4 | angiopoietin-like 4 | 0.101865 |
| B2M | beta-2-microglobulin | 0.094904 |
| VEGFA | vascular endothelial growth factor A | 0.0863529 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0742062 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0663279 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0651314 |
| SMAD3 | SMAD family member 3 | 0.0651102 |
| HDAC9 | histone deacetylase 9 | 0.0643454 |
| PLEC | plectin | 0.0629095 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0605027 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0596021 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0571966 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0561003 |
| FHIT | fragile histidine triad | 0.055092 |
| SP100 | SP100 nuclear antigen | 0.0531755 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.052533 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0457715 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0442578 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.044119 |
| COL5A1 | collagen, type V, alpha 1 | 0.0440908 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0438594 |
| NAV1 | neuron navigator 1 | 0.0420379 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0415239 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0412234 |
| SFTPA2 | surfactant protein A2 | 0.0409629 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0407588 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0395368 |
| HLA-A | major histocompatibility complex, class I, A | 0.0394723 |
| FAT1 | FAT atypical cadherin 1 | 0.038342 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0381522 |
| ASPH | aspartate beta-hydroxylase | 0.0377257 |
| LOXL2 | lysyl oxidase-like 2 | 0.0372467 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0362664 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0361118 |
| SVIL | supervillin | 0.0355878 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0347207 |
| RPS17 | ribosomal protein S17 | 0.0346563 |
| RPS12 | ribosomal protein S12 | 0.0340104 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0339555 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0339524 |
| FAM20C | family with sequence similarity 20, member C | 0.0338829 |
| MX1 | MX dynamin-like GTPase 1 | 0.0338073 |
| APP | amyloid beta (A4) precursor protein | 0.0334361 |
| CD44 | CD44 molecule (Indian blood group) | 0.0331867 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0326398 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0322787 |
| IFI44L | interferon-induced protein 44-like | 0.032135 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0315816 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0308294 |
| SQSTM1 | sequestosome 1 | 0.0307577 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0307361 |
| RPS6 | ribosomal protein S6 | 0.0305333 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0302919 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.029848 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0297921 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0297211 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0294996 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0293283 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0293114 |
| RPL37A | ribosomal protein L37a | 0.0292691 |
| HLA-E | major histocompatibility complex, class I, E | 0.0290693 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0289176 |
| H1-0 | H1.0 linker histone | 0.0285336 |
| PMP22 | peripheral myelin protein 22 | 0.0285127 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.028298 |
| RUNX1 | runt-related transcription factor 1 | 0.0282136 |
| RPS8 | ribosomal protein S8 | 0.0280815 |
| RPL3 | ribosomal protein L3 | 0.0273721 |
| MCL1 | myeloid cell leukemia 1 | 0.0270742 |
| AFAP1 | actin filament associated protein 1 | 0.0269251 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0269196 |
| SMYD3 | SET and MYND domain containing 3 | 0.0268454 |
| RNF213 | ring finger protein 213 | 0.0267422 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | 0.0267356 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0266414 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.026493 |
| RPL31 | ribosomal protein L31 | 0.0262514 |
| FLNB | filamin B, beta | 0.0262513 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.025299 |
| HLA-C | major histocompatibility complex, class I, C | 0.0252876 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0252802 |
| MTSS1 | metastasis suppressor 1 | 0.0250223 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0246498 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0245828 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0245554 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0243954 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0242886 |
| NONO | non-POU domain containing, octamer-binding | 0.0241484 |
| RPLP1 | ribosomal protein, large, P1 | 0.0239068 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0237642 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0234964 |
| RPL11 | ribosomal protein L11 | 0.0233374 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0232129 |
| WWOX | WW domain containing oxidoreductase | 0.0229017 |
| SEPTIN9 | septin 9 | 0.0227616 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0224337 |
| MT2A | metallothionein 2A | 0.0223715 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.296175 |
| FN1 | fibronectin 1 | -0.229953 |
| COL1A2 | collagen, type I, alpha 2 | -0.121025 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.103181 |
| TPM4 | tropomyosin 4 | -0.0654951 |
| PGK1 | phosphoglycerate kinase 1 | -0.0630707 |
| GOLGA4 | golgin A4 | -0.0574332 |
| POTEF | POTE ankyrin domain family, member F | -0.0551955 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0546333 |
| CENPF | centromere protein F, 350/400kDa | -0.0520928 |
| CD109 | CD109 molecule | -0.0477948 |
| RTN4 | reticulon 4 | -0.0470263 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0468553 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0445195 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0444908 |
| NDRG1 | N-myc downstream regulated 1 | -0.0425682 |
| COL1A1 | collagen, type I, alpha 1 | -0.0415495 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0413612 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0390022 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0389382 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0376273 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0359075 |
| SETD5 | SET domain containing 5 | -0.0357841 |
| ZNF292 | zinc finger protein 292 | -0.0349339 |
| SRP54 | signal recognition particle 54kDa | -0.034905 |
| TFG | TRK-fused gene | -0.0343216 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0336884 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0330738 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0325467 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0314474 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0312929 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0305349 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.030176 |
| DIAPH3 | diaphanous-related formin 3 | -0.0298828 |
| GNAS | GNAS complex locus | -0.0295911 |
| TPX2 | TPX2, microtubule-associated | -0.0294762 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0283855 |
| CALU | calumenin | -0.0279059 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.027771 |
| COPA | coatomer protein complex, subunit alpha | -0.0277091 |
| WASF2 | WAS protein family, member 2 | -0.0276695 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0276053 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0272476 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0267261 |
| NUP58 | nucleoporin 58 | -0.0265668 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0259049 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0257419 |
| ARF4 | ADP-ribosylation factor 4 | -0.0255417 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0254391 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0251797 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0251548 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.02499 |
| RNF24 | ring finger protein 24 | -0.0245616 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0243791 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0240245 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0239822 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0239069 |
| LOX | lysyl oxidase | -0.0238858 |
| S100A6 | S100 calcium binding protein A6 | -0.0235774 |
| COL5A2 | collagen, type V, alpha 2 | -0.0235456 |
| TMEM39A | transmembrane protein 39A | -0.0232257 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0229324 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0226625 |
| CENPE | centromere protein E, 312kDa | -0.0224203 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0222247 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0219784 |
| SEPTIN7 | septin 7 | -0.0218508 |
| FAM162A | family with sequence similarity 162, member A | -0.0217291 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0216523 |
| ECT2 | epithelial cell transforming 2 | -0.021531 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0214872 |
| PFN1 | profilin 1 | -0.0214847 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0214067 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0212711 |
| MKI67 | marker of proliferation Ki-67 | -0.0212405 |
| CALD1 | caldesmon 1 | -0.0212253 |
| ATP13A3 | ATPase type 13A3 | -0.0212239 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.021091 |
| MORF4L2 | mortality factor 4 like 2 | -0.0210316 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0207277 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0206185 |
| INSIG2 | insulin induced gene 2 | -0.0205613 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0205402 |
| TMEM165 | transmembrane protein 165 | -0.0205392 |
| RBM39 | RNA binding motif protein 39 | -0.0204495 |
| MEF2A | myocyte enhancer factor 2A | -0.0203292 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0203264 |
| MMP12 | matrix metallopeptidase 12 | -0.0202784 |
| SEC24D | SEC24 family member D | -0.0201656 |
| PLIN2 | perilipin 2 | -0.0201419 |
| QKI | QKI, KH domain containing, RNA binding | -0.02009 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0199869 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0199173 |
| MYADM | myeloid-associated differentiation marker | -0.0198964 |
| FAM13A | family with sequence similarity 13, member A | -0.0198847 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0198546 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0198418 |
| USP3 | ubiquitin specific peptidase 3 | -0.0198004 |
| SGO2 | shugoshin 2 | -0.0197661 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.019715 |
