| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Minodronic acid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.208288 |
| AHNAK | AHNAK nucleoprotein | 0.135441 |
| EGFR | epidermal growth factor receptor | 0.120821 |
| PRELID2 | PRELI domain containing 2 | 0.0928841 |
| TMSB4X | thymosin beta 4, X-linked | 0.0926059 |
| PKM | pyruvate kinase, muscle | 0.0792327 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0754839 |
| HDAC9 | histone deacetylase 9 | 0.0751529 |
| FLNB | filamin B, beta | 0.0739026 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0644775 |
| VCL | vinculin | 0.0632978 |
| RPL3 | ribosomal protein L3 | 0.0612362 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0584618 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0575315 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0572658 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.054745 |
| GLI3 | GLI family zinc finger 3 | 0.0540523 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.05335 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0518458 |
| PDGFC | platelet derived growth factor C | 0.0514996 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0509666 |
| MYO5C | myosin VC | 0.0500987 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.049359 |
| H1-4 | H1.4 linker histone, cluster member | 0.0486381 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0479958 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.047818 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0474958 |
| GLI2 | GLI family zinc finger 2 | 0.0464593 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0461045 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0460149 |
| SMYD3 | SET and MYND domain containing 3 | 0.0435422 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0426447 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0421042 |
| ZNF608 | zinc finger protein 608 | 0.0416837 |
| RPL37A | ribosomal protein L37a | 0.0415058 |
| RPL4 | ribosomal protein L4 | 0.0412152 |
| APP | amyloid beta (A4) precursor protein | 0.0410155 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0400844 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0398694 |
| CPNE1 | copine I | 0.0394841 |
| MACROD2 | MACRO domain containing 2 | 0.0392026 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0389362 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0389142 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0380275 |
| FOXP1 | forkhead box P1 | 0.0370155 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0362676 |
| INTS6 | integrator complex subunit 6 | 0.0359578 |
| RPL19 | ribosomal protein L19 | 0.0358922 |
| ZNF217 | zinc finger protein 217 | 0.0354577 |
| RPL7A | ribosomal protein L7a | 0.0347509 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0347426 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0346851 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0343311 |
| ANXA1 | annexin A1 | 0.0342354 |
| RPS15A | ribosomal protein S15a | 0.0315401 |
| SFTPA2 | surfactant protein A2 | 0.0313743 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0313269 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.030535 |
| DST | dystonin | 0.0304791 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0304567 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0302446 |
| KLC1 | kinesin light chain 1 | 0.0301828 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0301103 |
| RPS3 | ribosomal protein S3 | 0.0300636 |
| TMEM65 | transmembrane protein 65 | 0.0297911 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0294924 |
| ATP9B | ATPase, class II, type 9B | 0.029328 |
| RPL26 | ribosomal protein L26 | 0.0291538 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0284095 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0281621 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0272029 |
| FER1L6 | fer-1-like family member 6 | 0.0271732 |
| HDLBP | high density lipoprotein binding protein | 0.0271291 |
| TRERF1 | transcriptional regulating factor 1 | 0.0270939 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0269853 |
| NONO | non-POU domain containing, octamer-binding | 0.0267565 |
| RPL13A | ribosomal protein L13a | 0.0267334 |
| RPS23 | ribosomal protein S23 | 0.026702 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0263025 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0261837 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | 0.0260854 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0260564 |
| CEP250 | centrosomal protein 250kDa | 0.0258651 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0256924 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0254991 |
| PARD3 | par-3 family cell polarity regulator | 0.0253626 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0251274 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0249548 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0249077 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.02482 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0247919 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0247767 |
| RPL35 | ribosomal protein L35 | 0.0245907 |
| RPS12 | ribosomal protein S12 | 0.0244273 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0244105 |
| RPS13 | ribosomal protein S13 | 0.0244019 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0241086 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0241084 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0240872 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0237109 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | -0.085972 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0856951 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.083521 |
| POTEF | POTE ankyrin domain family, member F | -0.06634 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0654428 |
| EVI5 | ecotropic viral integration site 5 | -0.0639407 |
| CENPF | centromere protein F, 350/400kDa | -0.0581982 |
| RPL35A | ribosomal protein L35a | -0.0567103 |
| PTMA | prothymosin, alpha | -0.0544869 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0523568 |
| ZNF292 | zinc finger protein 292 | -0.0471998 |
| TFG | TRK-fused gene | -0.0450174 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0441744 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0439117 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0431124 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0424364 |
| PCBP2 | poly(rC) binding protein 2 | -0.0414457 |
| RBM25 | RNA binding motif protein 25 | -0.0411697 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0401855 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0399766 |
| PFN1 | profilin 1 | -0.03986 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0398201 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0377446 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0371035 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0365376 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0350668 |
| USP3 | ubiquitin specific peptidase 3 | -0.0347704 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0344177 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0332648 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0313965 |
| TMEM41B | transmembrane protein 41B | -0.031355 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0309379 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0307681 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0305671 |
| SEPTIN7 | septin 7 | -0.0300949 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0292963 |
| TMEM87A | transmembrane protein 87A | -0.0291613 |
| DSTN | destrin (actin depolymerizing factor) | -0.0284222 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0279594 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0279478 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0274136 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0272952 |
| CBX3 | chromobox homolog 3 | -0.0266369 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0261321 |
| SRP54 | signal recognition particle 54kDa | -0.0258103 |
| SBF2 | SET binding factor 2 | -0.0256675 |
| HMGB1 | high mobility group box 1 | -0.0255661 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0253939 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0250983 |
| FAM13A | family with sequence similarity 13, member A | -0.0250847 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.024959 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0247599 |
| NF1 | neurofibromin 1 | -0.0247555 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0241672 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0240004 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0239777 |
| ATN1 | atrophin 1 | -0.0239661 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0237439 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0237142 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.0236646 |
| SEC24A | SEC24 family member A | -0.0236565 |
| RPL27A | ribosomal protein L27a | -0.0232915 |
| S100A6 | S100 calcium binding protein A6 | -0.0231899 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0231237 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0230989 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0229121 |
| WDR45B | WD repeat domain 45B | -0.0229115 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0228719 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.022704 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0225983 |
| HELZ | helicase with zinc finger | -0.0225733 |
| MKI67 | marker of proliferation Ki-67 | -0.0225632 |
| B2M | beta-2-microglobulin | -0.0225585 |
| MT2A | metallothionein 2A | -0.0225496 |
| IGF2 | insulin-like growth factor 2 | -0.0225343 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0223769 |
| DEK | DEK proto-oncogene | -0.0223409 |
| NBAS | neuroblastoma amplified sequence | -0.0218688 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0218464 |
| NEBL | nebulette | -0.0218048 |
| RLF | rearranged L-myc fusion | -0.0217961 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0215799 |
| NUP58 | nucleoporin 58 | -0.0214842 |
| SETD5 | SET domain containing 5 | -0.0213572 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0213513 |
| THOC2 | THO complex 2 | -0.0212202 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0212038 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0211929 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0208897 |
| NKTR | natural killer cell triggering receptor | -0.0208321 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0206615 |
| TBK1 | TANK-binding kinase 1 | -0.0204176 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0203963 |
| MTDH | metadherin | -0.0202691 |
| DIAPH3 | diaphanous-related formin 3 | -0.0201744 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0200766 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0200107 |
| CCDC88A | coiled-coil domain containing 88A | -0.0198436 |
| CCNL1 | cyclin L1 | -0.0198202 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0196183 |