| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.267725 |
| COL6A3 | collagen, type VI, alpha 3 | 0.135455 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.114288 |
| CD44 | CD44 molecule (Indian blood group) | 0.0805354 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.079462 |
| GLIS3 | GLIS family zinc finger 3 | 0.0790412 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0688935 |
| HLA-B | major histocompatibility complex, class I, B | 0.0683065 |
| VEGFA | vascular endothelial growth factor A | 0.0677141 |
| VIM | vimentin | 0.0672547 |
| HMGA2 | high mobility group AT-hook 2 | 0.0594048 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0572949 |
| HDAC9 | histone deacetylase 9 | 0.0559783 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0505973 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.048956 |
| DST | dystonin | 0.048307 |
| VCL | vinculin | 0.0481791 |
| BICC1 | BicC family RNA binding protein 1 | 0.0481714 |
| ASPH | aspartate beta-hydroxylase | 0.0479706 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0474282 |
| FRMD4A | FERM domain containing 4A | 0.0472535 |
| SMAD3 | SMAD family member 3 | 0.0461215 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0425456 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0422427 |
| SFTPA2 | surfactant protein A2 | 0.0410521 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0399577 |
| MSN | moesin | 0.0399222 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0398923 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.038992 |
| ENO1 | enolase 1, (alpha) | 0.0386811 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0386198 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0378616 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0375734 |
| AHNAK | AHNAK nucleoprotein | 0.0373247 |
| ATXN1 | ataxin 1 | 0.0365172 |
| NAV1 | neuron navigator 1 | 0.0363766 |
| TMSB10 | thymosin beta 10 | 0.0363641 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0357767 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0349272 |
| GPC6 | glypican 6 | 0.0347339 |
| CDH13 | cadherin 13 | 0.0342974 |
| VCAN | versican | 0.0334334 |
| MLPH | melanophilin | 0.0331182 |
| RPS12 | ribosomal protein S12 | 0.0328324 |
| CALR | calreticulin | 0.0326218 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0325711 |
| SEPTIN9 | septin 9 | 0.0317879 |
| RNF213 | ring finger protein 213 | 0.0317138 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0303776 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0298969 |
| SYNJ2 | synaptojanin 2 | 0.0295824 |
| STC1 | stanniocalcin 1 | 0.0294535 |
| KYNU | kynureninase | 0.029452 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0293691 |
| RPS3 | ribosomal protein S3 | 0.029229 |
| RPL37A | ribosomal protein L37a | 0.0291746 |
| SQSTM1 | sequestosome 1 | 0.029111 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0287464 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0285677 |
| COL5A1 | collagen, type V, alpha 1 | 0.0280307 |
| LDHA | lactate dehydrogenase A | 0.0277402 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0275689 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0275133 |
| FAM20C | family with sequence similarity 20, member C | 0.0274333 |
| MT2A | metallothionein 2A | 0.0273711 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.027323 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0271125 |
| NONO | non-POU domain containing, octamer-binding | 0.026935 |
| SVIL | supervillin | 0.0266145 |
| SMYD3 | SET and MYND domain containing 3 | 0.0259305 |
| APP | amyloid beta (A4) precursor protein | 0.0259077 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.025437 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0250538 |
| TNS3 | tensin 3 | 0.0247215 |
| EPAS1 | endothelial PAS domain protein 1 | 0.024233 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0239909 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0238198 |
| RAD51B | RAD51 paralog B | 0.0237717 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0236017 |
| CEP250 | centrosomal protein 250kDa | 0.0232329 |
| EFNA5 | ephrin-A5 | 0.02317 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0229473 |
| NAV2 | neuron navigator 2 | 0.0227157 |
| GOLGB1 | golgin B1 | 0.0226419 |
| INTS6 | integrator complex subunit 6 | 0.022347 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.022265 |
| EGFR | epidermal growth factor receptor | 0.022263 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0220115 |
| RPS27A | ribosomal protein S27a | 0.0219927 |
| PHF3 | PHD finger protein 3 | 0.0216829 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0216615 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0211579 |
| TMEM132D | transmembrane protein 132D | 0.021049 |
| RPL35 | ribosomal protein L35 | 0.0209228 |
| FNDC3B | fibronectin type III domain containing 3B | 0.020884 |
| VMP1 | vacuole membrane protein 1 | 0.0208729 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.02086 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0205974 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0204219 |
| IER3 | immediate early response 3 | 0.0204161 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0873258 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0628811 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0562612 |
| CADM1 | cell adhesion molecule 1 | -0.0550595 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0502223 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0487982 |
| FN1 | fibronectin 1 | -0.0487139 |
| ZNF292 | zinc finger protein 292 | -0.0377243 |
| HELZ | helicase with zinc finger | -0.0314145 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0314028 |
| SPAG9 | sperm associated antigen 9 | -0.0306711 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0294873 |
| GOLGA4 | golgin A4 | -0.0292646 |
| PCBP2 | poly(rC) binding protein 2 | -0.0282195 |
| QKI | QKI, KH domain containing, RNA binding | -0.0280884 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0254169 |
| WTAP | Wilms tumor 1 associated protein | -0.0249759 |
| ATP13A3 | ATPase type 13A3 | -0.0245009 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0237382 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0237105 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0233707 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0231869 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.022921 |
| YBX1 | Y box binding protein 1 | -0.021391 |
| TMEM123 | transmembrane protein 123 | -0.0211661 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0211426 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0209309 |
| CCNL1 | cyclin L1 | -0.0208907 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0207881 |
| RLF | rearranged L-myc fusion | -0.0205415 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0205319 |
| WDR45B | WD repeat domain 45B | -0.0202326 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0201295 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.019773 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0196406 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0193482 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0193321 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0193018 |
| TFG | TRK-fused gene | -0.0191613 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0190684 |
| PHIP | pleckstrin homology domain interacting protein | -0.0190334 |
| TAPBP | TAP binding protein (tapasin) | -0.018844 |
| POTEF | POTE ankyrin domain family, member F | -0.0179113 |
| RPLP0 | ribosomal protein, large, P0 | -0.0178218 |
| HMGA1 | high mobility group AT-hook 1 | -0.0174279 |
| RYBP | RING1 and YY1 binding protein | -0.0174045 |
| ADM | adrenomedullin | -0.017384 |
| SRP54 | signal recognition particle 54kDa | -0.0173183 |
| GNAS | GNAS complex locus | -0.0172661 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0172456 |
| RNF145 | ring finger protein 145 | -0.0171563 |
| RBM39 | RNA binding motif protein 39 | -0.0168229 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0167794 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0165605 |
| ZNF207 | zinc finger protein 207 | -0.0165375 |
| USP37 | ubiquitin specific peptidase 37 | -0.0162997 |
| ANLN | anillin, actin binding protein | -0.0159269 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0158213 |
| SEC24A | SEC24 family member A | -0.0157987 |
| UVRAG | UV radiation resistance associated | -0.0157075 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0154864 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0153513 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0152119 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0151835 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0150621 |
| RAB1A | RAB1A, member RAS oncogene family | -0.014626 |
| MATR3 | matrin 3 | -0.0144707 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0144474 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0144062 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0142635 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0141588 |
| NUP58 | nucleoporin 58 | -0.0140045 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0139531 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0139456 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0138785 |
| SEPTIN7 | septin 7 | -0.0137939 |
| NUP153 | nucleoporin 153kDa | -0.0137541 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.013726 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0137258 |
| TKT | transketolase | -0.0136941 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0135959 |
| RPL35A | ribosomal protein L35a | -0.0135316 |
| USP3 | ubiquitin specific peptidase 3 | -0.0133147 |
| DEK | DEK proto-oncogene | -0.0132396 |
| SNX3 | sorting nexin 3 | -0.0129622 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0128048 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0128003 |
| HBS1L | HBS1-like translational GTPase | -0.0126821 |
| RPL39 | ribosomal protein L39 | -0.0125717 |
| OGA | O-GlcNAcase | -0.0125097 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0124873 |
| PER1 | period circadian clock 1 | -0.0124451 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0123891 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0122851 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0122772 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0120406 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0118027 |
| CLINT1 | clathrin interactor 1 | -0.0117769 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0116501 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0115315 |
