| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Minodronic acid_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.102419 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0885026 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0879623 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0878925 |
| ANGPTL4 | angiopoietin-like 4 | 0.0716062 |
| AHNAK | AHNAK nucleoprotein | 0.0700011 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0696289 |
| LDHA | lactate dehydrogenase A | 0.0664248 |
| INTS6 | integrator complex subunit 6 | 0.066361 |
| HMGA2 | high mobility group AT-hook 2 | 0.0640034 |
| DST | dystonin | 0.0591057 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0547713 |
| FMNL2 | formin-like 2 | 0.0535682 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0499182 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0498785 |
| SMAD3 | SMAD family member 3 | 0.0451819 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0417985 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0386699 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0381835 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0369851 |
| ASPH | aspartate beta-hydroxylase | 0.0368721 |
| CEP250 | centrosomal protein 250kDa | 0.0365642 |
| SVIL | supervillin | 0.0359697 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0357322 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0354681 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0350631 |
| CAVIN1 | caveolae associated protein 1 | 0.0339684 |
| ATXN1 | ataxin 1 | 0.033772 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0329578 |
| CANX | calnexin | 0.0326507 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0324191 |
| EGFR | epidermal growth factor receptor | 0.0323968 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0321454 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0320222 |
| ANXA1 | annexin A1 | 0.0318617 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0312515 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0312267 |
| PLEC | plectin | 0.0311086 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0308446 |
| CPNE1 | copine I | 0.0307622 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0302322 |
| SDC4 | syndecan 4 | 0.0298176 |
| CAPRIN2 | caprin family member 2 | 0.0297077 |
| NDRG1 | N-myc downstream regulated 1 | 0.0295626 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0294131 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0292232 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0291914 |
| SEPTIN9 | septin 9 | 0.028538 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0283856 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0283333 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.027603 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0273037 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0266964 |
| GPC5 | glypican 5 | 0.0264388 |
| PHF3 | PHD finger protein 3 | 0.0263082 |
| RAI14 | retinoic acid induced 14 | 0.0261903 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0261375 |
| COL5A1 | collagen, type V, alpha 1 | 0.0259444 |
| PYGL | phosphorylase, glycogen, liver | 0.0258268 |
| PTK2 | protein tyrosine kinase 2 | 0.0257506 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.025733 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.025286 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0252051 |
| AEBP2 | AE binding protein 2 | 0.0250293 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0247138 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0243752 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0242115 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0241087 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0240657 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0240042 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0238227 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0234262 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0231718 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0230593 |
| PRKCA | protein kinase C, alpha | 0.0230046 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0228658 |
| PODXL | podocalyxin-like | 0.022821 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0226121 |
| FMN1 | formin 1 | 0.0223475 |
| ATM | ATM serine/threonine kinase | 0.021754 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0213269 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.021305 |
| RNF213 | ring finger protein 213 | 0.0210304 |
| PRR16 | proline rich 16 | 0.0210073 |
| SFTPA2 | surfactant protein A2 | 0.0209778 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.02097 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0209464 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0207475 |
| FLNB | filamin B, beta | 0.0205144 |
| ACTG1 | actin gamma 1 | 0.0204301 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0203341 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0201685 |
| ACTN1 | actinin, alpha 1 | 0.0199787 |
| SYNJ2 | synaptojanin 2 | 0.0198977 |
| FLNA | filamin A, alpha | 0.0195043 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0194986 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.019453 |
| VCL | vinculin | 0.019409 |
| ANO6 | anoctamin 6 | 0.0191284 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0189917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0700414 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0518184 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.045192 |
| ZNF292 | zinc finger protein 292 | -0.0412561 |
| DIAPH3 | diaphanous-related formin 3 | -0.0383994 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0359251 |
| CENPF | centromere protein F, 350/400kDa | -0.03553 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0346112 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0335813 |
| TPX2 | TPX2, microtubule-associated | -0.0330564 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0318498 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0313286 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0308765 |
| CKAP2 | cytoskeleton associated protein 2 | -0.029823 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0297002 |
| ECT2 | epithelial cell transforming 2 | -0.0296661 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0292348 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0278719 |
| PCBP2 | poly(rC) binding protein 2 | -0.0276487 |
| SPAG9 | sperm associated antigen 9 | -0.0275826 |
| HJURP | Holliday junction recognition protein | -0.0275793 |
| DNER | delta/notch-like EGF repeat containing | -0.0275713 |
| SGO2 | shugoshin 2 | -0.0270368 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0268867 |
| YBX3 | Y box binding protein 3 | -0.0267792 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0265516 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0258148 |
| TXNRD1 | thioredoxin reductase 1 | -0.0249276 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0248695 |
| MKI67 | marker of proliferation Ki-67 | -0.0234227 |
| KIF5B | kinesin family member 5B | -0.0233225 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0221389 |
| KIAA1328 | KIAA1328 | -0.0221052 |
| KIF23 | kinesin family member 23 | -0.0220797 |
| CKAP2L | cytoskeleton associated protein 2-like | -0.0219823 |
| KIAA1958 | KIAA1958 | -0.0217058 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0214205 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0212351 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0211842 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0210333 |
| R3HDM1 | R3H domain containing 1 | -0.0209365 |
| GOLGA4 | golgin A4 | -0.0206198 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0205164 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0202273 |
| BSG | basigin (Ok blood group) | -0.0197818 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0196755 |
| RBM25 | RNA binding motif protein 25 | -0.0196685 |
| CENPE | centromere protein E, 312kDa | -0.0195681 |
| RSF1 | remodeling and spacing factor 1 | -0.0194808 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0191618 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0191098 |
| PRR11 | proline rich 11 | -0.0190125 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.018793 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0186408 |
| TTK | TTK protein kinase | -0.0181875 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0180381 |
| HBS1L | HBS1-like translational GTPase | -0.0180071 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0178701 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0177099 |
| CUL5 | cullin 5 | -0.0176062 |
| CAPN7 | calpain 7 | -0.017498 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | -0.0173404 |
| SEPTIN7 | septin 7 | -0.0173339 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0172135 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0170654 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0169895 |
| BPTF | bromodomain PHD finger transcription factor | -0.0168116 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0167903 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.016768 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0166676 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0164954 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0164461 |
| INVS | inversin | -0.0164203 |
| CCDC14 | coiled-coil domain containing 14 | -0.0162077 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0161305 |
| WDR43 | WD repeat domain 43 | -0.0161076 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0160522 |
| RBM27 | RNA binding motif protein 27 | -0.0160295 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0160118 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0159394 |
| KIF2A | kinesin heavy chain member 2A | -0.0157918 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0157779 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.015753 |
| ATXN2 | ataxin 2 | -0.0156949 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | -0.0154706 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0153861 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0153855 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0152181 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0152119 |
| CENPK | centromere protein K | -0.0152081 |
| NAV2 | neuron navigator 2 | -0.0151694 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0150975 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0150002 |
| TFG | TRK-fused gene | -0.0148853 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0148581 |
| RPL27A | ribosomal protein L27a | -0.0147746 |
| CEP192 | centrosomal protein 192kDa | -0.0147343 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0147307 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.014712 |
| PCM1 | pericentriolar material 1 | -0.014668 |
