| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Minodronic acid perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Minodronic acid_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.235967 |
| FN1 | fibronectin 1 | 0.199994 |
| INHBA | inhibin, beta A | 0.152338 |
| CD44 | CD44 molecule (Indian blood group) | 0.105929 |
| COL6A3 | collagen, type VI, alpha 3 | 0.103428 |
| HMGA2 | high mobility group AT-hook 2 | 0.0780299 |
| MMP1 | matrix metallopeptidase 1 | 0.059299 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0580868 |
| EMP1 | epithelial membrane protein 1 | 0.0521118 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.051163 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0491246 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.046773 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0457129 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0445412 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0442244 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0437317 |
| MYO10 | myosin X | 0.0391447 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0384937 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0362565 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0362319 |
| AHNAK | AHNAK nucleoprotein | 0.0355389 |
| NAV1 | neuron navigator 1 | 0.0338321 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0335258 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0324057 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0320252 |
| LOXL2 | lysyl oxidase-like 2 | 0.0315873 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0290727 |
| SMAD3 | SMAD family member 3 | 0.0286302 |
| EGR1 | early growth response 1 | 0.0264942 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0261641 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0256616 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0253403 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0253267 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0248909 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.023513 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0230289 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0225547 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0222516 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0221085 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.020816 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0206877 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0206457 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0205005 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0202494 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0201773 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0199394 |
| TMSB4X | thymosin beta 4, X-linked | 0.0193872 |
| NUMB | numb homolog (Drosophila) | 0.0193499 |
| OSMR | oncostatin M receptor | 0.019274 |
| RUNX1 | runt-related transcription factor 1 | 0.0190383 |
| SPAG9 | sperm associated antigen 9 | 0.0187838 |
| LOX | lysyl oxidase | 0.0186844 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0185615 |
| EGFR | epidermal growth factor receptor | 0.0185024 |
| PDE8A | phosphodiesterase 8A | 0.0183129 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0182953 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0182834 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0182423 |
| FBN1 | fibrillin 1 | 0.0179726 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0178256 |
| PLPP3 | phospholipid phosphatase 3 | 0.0177276 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0175927 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0175517 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0174498 |
| ANO6 | anoctamin 6 | 0.0171714 |
| NOTCH2 | notch 2 | 0.0171236 |
| IL6ST | interleukin 6 signal transducer | 0.0170858 |
| GLIS3 | GLIS family zinc finger 3 | 0.0170563 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0169575 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0168598 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0168511 |
| FRMD6 | FERM domain containing 6 | 0.01669 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0165667 |
| SSH1 | slingshot protein phosphatase 1 | 0.0164404 |
| SEPTIN9 | septin 9 | 0.0163801 |
| VEGFA | vascular endothelial growth factor A | 0.0163352 |
| NDRG1 | N-myc downstream regulated 1 | 0.016294 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0161078 |
| ETV3 | ets variant 3 | 0.0160972 |
| FOXP1 | forkhead box P1 | 0.0160071 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0155045 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0154739 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0153825 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0151341 |
| VIM | vimentin | 0.0151187 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0150385 |
| H1-0 | H1.0 linker histone | 0.0149586 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0147379 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0144534 |
| PALLD | palladin, cytoskeletal associated protein | 0.0143357 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0142297 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0142264 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0142163 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0140552 |
| YBX3 | Y box binding protein 3 | 0.0140173 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.014017 |
| SYNJ2 | synaptojanin 2 | 0.0139185 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0136497 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0136222 |
| CTSB | cathepsin B | 0.0135787 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.105571 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0798407 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0585697 |
| TMSB10 | thymosin beta 10 | -0.0500504 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0457631 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0442104 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0408637 |
| OXR1 | oxidation resistance 1 | -0.0403237 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0370133 |
| RPL37A | ribosomal protein L37a | -0.0357988 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0336324 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0332708 |
| ACTG1 | actin gamma 1 | -0.0320089 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0311561 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0296544 |
| RPS12 | ribosomal protein S12 | -0.0279659 |
| RPS6 | ribosomal protein S6 | -0.0279297 |
| RPS3 | ribosomal protein S3 | -0.0251871 |
| HLA-B | major histocompatibility complex, class I, B | -0.0250629 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0245381 |
| GOLGA4 | golgin A4 | -0.0242183 |
| MMP12 | matrix metallopeptidase 12 | -0.0237285 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0235857 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0231886 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0228188 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0222453 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0222006 |
| INTS6 | integrator complex subunit 6 | -0.0221367 |
| POTEF | POTE ankyrin domain family, member F | -0.0220149 |
| TMEM165 | transmembrane protein 165 | -0.0219415 |
| RPS8 | ribosomal protein S8 | -0.0211901 |
| RPS29 | ribosomal protein S29 | -0.0198777 |
| RPL31 | ribosomal protein L31 | -0.0198328 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0197499 |
| COL5A1 | collagen, type V, alpha 1 | -0.0196386 |
| COL1A2 | collagen, type I, alpha 2 | -0.0187542 |
| RPL38 | ribosomal protein L38 | -0.018307 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0178412 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0174091 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0172115 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0171323 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0163813 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.016341 |
| RPS17 | ribosomal protein S17 | -0.0161524 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0160584 |
| RPS23 | ribosomal protein S23 | -0.0157524 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0153161 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0152406 |
| CALD1 | caldesmon 1 | -0.0150721 |
| RPS19 | ribosomal protein S19 | -0.0150202 |
| OGA | O-GlcNAcase | -0.0146425 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0145569 |
| RPL11 | ribosomal protein L11 | -0.0143362 |
| RPS27A | ribosomal protein S27a | -0.014055 |
| RPL28 | ribosomal protein L28 | -0.0140477 |
| RPLP1 | ribosomal protein, large, P1 | -0.0140096 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.013936 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.013872 |
| RPL34 | ribosomal protein L34 | -0.0138433 |
| FNIP1 | folliculin interacting protein 1 | -0.0137845 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0136814 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0134861 |
| RPS13 | ribosomal protein S13 | -0.0132428 |
| HELZ | helicase with zinc finger | -0.0127788 |
| PRELID2 | PRELI domain containing 2 | -0.012754 |
| ITGA1 | integrin, alpha 1 | -0.0123188 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0122828 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0122261 |
| RPL9 | ribosomal protein L9 | -0.0121069 |
| MYOF | myoferlin | -0.01206 |
| SEC24D | SEC24 family member D | -0.0119858 |
| RPL19 | ribosomal protein L19 | -0.0119785 |
| ANK2 | ankyrin 2, neuronal | -0.011973 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0118278 |
| ANO10 | anoctamin 10 | -0.0117779 |
| NAV2 | neuron navigator 2 | -0.011698 |
| RPL13A | ribosomal protein L13a | -0.0116547 |
| RPL35 | ribosomal protein L35 | -0.0116495 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0116463 |
| RAD51B | RAD51 paralog B | -0.0115819 |
| DST | dystonin | -0.0115192 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0115164 |
| PCDH9 | protocadherin 9 | -0.0115008 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0114576 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -0.0114434 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.011414 |
| ZNF638 | zinc finger protein 638 | -0.0108876 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0108628 |
| RPS11 | ribosomal protein S11 | -0.010833 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0106503 |
| RPLP2 | ribosomal protein, large, P2 | -0.0106062 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0105655 |
| RNF150 | ring finger protein 150 | -0.0105004 |
| RPL26 | ribosomal protein L26 | -0.0104835 |
| PTMA | prothymosin, alpha | -0.0103903 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0103723 |
| GOLGB1 | golgin B1 | -0.0103498 |
| SEPTIN11 | septin 11 | -0.0102556 |
| S100A9 | S100 calcium binding protein A9 | -0.0102123 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.010179 |
