Mitophagy Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-5205647
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Genes

39 proteins participating in the Mitophagy pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ATG12 autophagy related 12
ATG5 autophagy related 5
ATG9A autophagy related 9A
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
FUNDC1 FUN14 domain containing 1
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MFN1 mitofusin 1
MFN2 mitofusin 2
MTERF3 mitochondrial transcription termination factor 3
OPTN optineurin
PGAM5 phosphoglycerate mutase family member 5
PINK1 PTEN induced putative kinase 1
PRKN parkin RBR E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBK1 TANK-binding kinase 1
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast)
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast)
TOMM70 translocase of outer mitochondrial membrane 70
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
ULK1 unc-51 like autophagy activating kinase 1
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2
VDAC3 voltage-dependent anion channel 3