Mitotic Spindle Checkpoint Gene Set
Dataset
Reactome Pathways 2014
Category
structural or functional annotations
Type
pathway
Description
A mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form. (Gene Ontology , GO_0071174 )
External Link
http://www.reactome.org/PathwayBrowser/#/R-HSA-69618
Similar Terms
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Genes
19 proteins participating in the Mitotic Spindle Checkpoint pathway from the Reactome Pathways dataset.
Symbol
Name
ANAPC1
anaphase promoting complex subunit 1
ANAPC10
anaphase promoting complex subunit 10
ANAPC11
anaphase promoting complex subunit 11
ANAPC2
anaphase promoting complex subunit 2
ANAPC4
anaphase promoting complex subunit 4
ANAPC5
anaphase promoting complex subunit 5
ANAPC7
anaphase promoting complex subunit 7
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
BUB3
BUB3 mitotic checkpoint protein
CDC16
cell division cycle 16
CDC20
cell division cycle 20
CDC23
cell division cycle 23
CDC26
cell division cycle 26
CDC27
cell division cycle 27
MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
UBE2C
ubiquitin-conjugating enzyme E2C
UBE2D1
ubiquitin-conjugating enzyme E2D 1
UBE2E1
ubiquitin-conjugating enzyme E2E 1
