| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mitoxantrone (dihydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mitoxantrone (dihydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.0637484 |
| EXOC4 | exocyst complex component 4 | 0.0436259 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0402262 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0359823 |
| DST | dystonin | 0.0341889 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0335052 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0314205 |
| GPC6 | glypican 6 | 0.0302546 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0301355 |
| INTS6 | integrator complex subunit 6 | 0.0282837 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0281663 |
| TLE4 | transducin-like enhancer of split 4 | 0.026725 |
| PDLIM5 | PDZ and LIM domain 5 | 0.026534 |
| SETBP1 | SET binding protein 1 | 0.0251255 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0249877 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0244719 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0243977 |
| PAX3 | paired box 3 | 0.0240716 |
| UTRN | utrophin | 0.0235619 |
| FRMD4A | FERM domain containing 4A | 0.023388 |
| MACROD2 | MACRO domain containing 2 | 0.0228674 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0224973 |
| SMYD3 | SET and MYND domain containing 3 | 0.0211558 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0210536 |
| ANK2 | ankyrin 2, neuronal | 0.0205847 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0199818 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0199524 |
| PRELID2 | PRELI domain containing 2 | 0.0194377 |
| VCL | vinculin | 0.0192464 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0190062 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0185044 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0177633 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0175809 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0173486 |
| NBEA | neurobeachin | 0.0163447 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0160915 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0160012 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0159712 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0158423 |
| IFRD1 | interferon-related developmental regulator 1 | 0.01584 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0157949 |
| LRRC23 | leucine rich repeat containing 23 | 0.0156527 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0155397 |
| NAV1 | neuron navigator 1 | 0.015538 |
| ATXN1 | ataxin 1 | 0.0151713 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0150098 |
| IPO9 | importin 9 | 0.01474 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0144494 |
| HMGA2 | high mobility group AT-hook 2 | 0.0142865 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0141586 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0139863 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0136481 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0132575 |
| AOPEP | aminopeptidase O (putative) | 0.0132499 |
| EFNA5 | ephrin-A5 | 0.0128595 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0127859 |
| SHISA5 | shisa family member 5 | 0.0127454 |
| CYTH3 | cytohesin 3 | 0.0127085 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0126904 |
| CTTNBP2 | cortactin binding protein 2 | 0.0125877 |
| RAD51B | RAD51 paralog B | 0.0122439 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0122288 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0122215 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0121073 |
| LYST | lysosomal trafficking regulator | 0.0120763 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0120529 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0119813 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0119405 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0118872 |
| MYO1E | myosin IE | 0.0118766 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0118279 |
| NABP1 | nucleic acid binding protein 1 | 0.0118082 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0117881 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0117462 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0111263 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.011074 |
| PCDH7 | protocadherin 7 | 0.0110511 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0110156 |
| AEBP2 | AE binding protein 2 | 0.010914 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0108098 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0107675 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0106883 |
| ADORA1 | adenosine A1 receptor | 0.010641 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0106046 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0105378 |
| CA8 | carbonic anhydrase VIII | 0.0105198 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0105078 |
| CCDC138 | coiled-coil domain containing 138 | 0.0104906 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0104291 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0103685 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0103498 |
| CFAP44 | cilia and flagella associated protein 44 | 0.0103362 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0102234 |
| PRKD1 | protein kinase D1 | 0.0101626 |
| RFX7 | regulatory factor X, 7 | 0.0101618 |
| MSI2 | musashi RNA-binding protein 2 | 0.0101511 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0101494 |
| AGMO | alkylglycerol monooxygenase | 0.010075 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.010014 |
| HMCN1 | hemicentin 1 | 0.00994961 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.38354 |
| VIM | vimentin | -0.259061 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.226447 |
| FN1 | fibronectin 1 | -0.181391 |
| VGF | VGF nerve growth factor inducible | -0.152703 |
| ENO1 | enolase 1, (alpha) | -0.111685 |
| TMSB10 | thymosin beta 10 | -0.100767 |
| S100A6 | S100 calcium binding protein A6 | -0.096101 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0864752 |
| MT2A | metallothionein 2A | -0.0803323 |
| HLA-B | major histocompatibility complex, class I, B | -0.0786185 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0758354 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0752889 |
| NDRG1 | N-myc downstream regulated 1 | -0.0744829 |
| TAGLN2 | transgelin 2 | -0.0732996 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0724102 |
| PKM | pyruvate kinase, muscle | -0.0694923 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0672706 |
| DCT | dopachrome tautomerase | -0.0620384 |
| UBC | ubiquitin C | -0.0618823 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0614375 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0612114 |
| POTEF | POTE ankyrin domain family, member F | -0.0567214 |
| CALU | calumenin | -0.055038 |
| PGK1 | phosphoglycerate kinase 1 | -0.0548755 |
| ACTG1 | actin gamma 1 | -0.053109 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0528085 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0491846 |
| SFTPA2 | surfactant protein A2 | -0.0473005 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0457585 |
| PTMA | prothymosin, alpha | -0.0456569 |
| LDHA | lactate dehydrogenase A | -0.04437 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0437737 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0435807 |
| LMNA | lamin A/C | -0.0408826 |
| B2M | beta-2-microglobulin | -0.0408155 |
| CD109 | CD109 molecule | -0.0401917 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0396344 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0395291 |
| TPI1 | triosephosphate isomerase 1 | -0.0394185 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0393955 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0393037 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0386895 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0384834 |
| S100A9 | S100 calcium binding protein A9 | -0.0384612 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0374821 |
| GDF15 | growth differentiation factor 15 | -0.0373351 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0370108 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0369548 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0369035 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0358902 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0358108 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0347619 |
| CALR | calreticulin | -0.0346457 |
| WDR45B | WD repeat domain 45B | -0.0345559 |
| RPLP1 | ribosomal protein, large, P1 | -0.0340518 |
| GNAS | GNAS complex locus | -0.0337996 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0337268 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0330039 |
| MT1X | metallothionein 1X | -0.032418 |
| CALD1 | caldesmon 1 | -0.0321596 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0312673 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0311049 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0310207 |
| RPS19 | ribosomal protein S19 | -0.0310166 |
| CD63 | CD63 molecule | -0.0309808 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0308634 |
| FTL | ferritin, light polypeptide | -0.0304731 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0303814 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0299815 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0299154 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0298861 |
| MTDH | metadherin | -0.0296369 |
| CTSD | cathepsin D | -0.0295292 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0293364 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0289163 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0286058 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0285131 |
| NPC1 | Niemann-Pick disease, type C1 | -0.02817 |
| RNF24 | ring finger protein 24 | -0.0276681 |
| GOLGA4 | golgin A4 | -0.0272341 |
| ZNF292 | zinc finger protein 292 | -0.0271872 |
| HLA-A | major histocompatibility complex, class I, A | -0.0270232 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0269161 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0268363 |
| IER3 | immediate early response 3 | -0.0265276 |
| RTN4 | reticulon 4 | -0.0264839 |
| FAM162A | family with sequence similarity 162, member A | -0.0262143 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0260931 |
| RPS12 | ribosomal protein S12 | -0.0258787 |
| MTPN | myotrophin | -0.0257633 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0257203 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0256556 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0252511 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0251301 |
| CENPF | centromere protein F, 350/400kDa | -0.0248043 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0247357 |
| CSNK1E | casein kinase 1, epsilon | -0.0244529 |
| RPS8 | ribosomal protein S8 | -0.0242747 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0242228 |
