| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mitoxantrone (dihydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mitoxantrone (dihydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.136338 |
| EXT1 | exostosin glycosyltransferase 1 | 0.126553 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0789196 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0764316 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0679961 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0568779 |
| NTN4 | netrin 4 | 0.0565729 |
| SMAD3 | SMAD family member 3 | 0.0537791 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0504324 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0503352 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0490557 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0458177 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0396366 |
| INTS6 | integrator complex subunit 6 | 0.0383042 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0336499 |
| KRT20 | keratin 20, type I | 0.0319237 |
| TMEM65 | transmembrane protein 65 | 0.0318062 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0316289 |
| CCNYL1 | cyclin Y-like 1 | 0.0312804 |
| TLE4 | transducin-like enhancer of split 4 | 0.030871 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0305727 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0305337 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0297976 |
| RASEF | RAS and EF-hand domain containing | 0.0296051 |
| DST | dystonin | 0.0295538 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0293976 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0287734 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0279973 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0270624 |
| EXPH5 | exophilin 5 | 0.0267378 |
| SGMS2 | sphingomyelin synthase 2 | 0.0267284 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0261907 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259829 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0258272 |
| VCL | vinculin | 0.0256083 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0254928 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0248594 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.024778 |
| TJP1 | tight junction protein 1 | 0.0243269 |
| ATXN1 | ataxin 1 | 0.0242789 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0237727 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0229361 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0223941 |
| FBXO32 | F-box protein 32 | 0.0217556 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.021313 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0211544 |
| TXNRD1 | thioredoxin reductase 1 | 0.0204499 |
| HYOU1 | hypoxia up-regulated 1 | 0.020056 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0200263 |
| NEBL | nebulette | 0.0199108 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0197274 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0196408 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0195012 |
| EFNB2 | ephrin-B2 | 0.0194728 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0190677 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0188478 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0186822 |
| SIK3 | SIK family kinase 3 | 0.0186631 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0186044 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.018549 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0184567 |
| DUSP16 | dual specificity phosphatase 16 | 0.0184146 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0182195 |
| USP53 | ubiquitin specific peptidase 53 | 0.0181361 |
| RND3 | Rho family GTPase 3 | 0.0180875 |
| TES | testin LIM domain protein | 0.0180721 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0178184 |
| ANXA1 | annexin A1 | 0.0177012 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0173031 |
| FOXO3 | forkhead box O3 | 0.0172174 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0171001 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0170602 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0167356 |
| SUCO | SUN domain containing ossification factor | 0.0166961 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0164858 |
| FAM107B | family with sequence similarity 107, member B | 0.0164154 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0163781 |
| TOP1 | topoisomerase (DNA) I | 0.0161737 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0161248 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0161008 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0160447 |
| FAM13A | family with sequence similarity 13, member A | 0.0160441 |
| MYOF | myoferlin | 0.0158546 |
| ATF3 | activating transcription factor 3 | 0.015816 |
| FAM135A | family with sequence similarity 135, member A | 0.0156969 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0156349 |
| EHF | ets homologous factor | 0.0156164 |
| RIGI | RNA sensor RIG-I | 0.0155781 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0155432 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0154646 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0154583 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.015372 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0151915 |
| ACVR1 | activin A receptor, type I | 0.0151369 |
| GLCCI1 | glucocorticoid induced 1 | 0.0151281 |
| STX3 | syntaxin 3 | 0.0150949 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0150535 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0149632 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0148848 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0148049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.162668 |
| SLC45A4 | solute carrier family 45, member 4 | -0.12656 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113101 |
| ACTN4 | actinin, alpha 4 | -0.0925019 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0880954 |
| AHNAK | AHNAK nucleoprotein | -0.0867002 |
| PTMA | prothymosin, alpha | -0.0842553 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0791403 |
| LYZ | lysozyme | -0.0783057 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0717744 |
| FTL | ferritin, light polypeptide | -0.0713805 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0693122 |
| RPS6 | ribosomal protein S6 | -0.064123 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0556237 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0552764 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0551967 |
| ACTG1 | actin gamma 1 | -0.0546815 |
| WASF2 | WAS protein family, member 2 | -0.0542253 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0538413 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0536324 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.053342 |
| FRY | furry homolog (Drosophila) | -0.0533165 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0531561 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0512346 |
| LDHA | lactate dehydrogenase A | -0.0511776 |
| KRT18 | keratin 18, type I | -0.0492992 |
| STK24 | serine/threonine kinase 24 | -0.048844 |
| POTEF | POTE ankyrin domain family, member F | -0.0485035 |
| JUP | junction plakoglobin | -0.0481973 |
| RPS19 | ribosomal protein S19 | -0.0478887 |
| TMSB10 | thymosin beta 10 | -0.0472415 |
| RPLP1 | ribosomal protein, large, P1 | -0.0471838 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0471637 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0471485 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0467719 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0443478 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.044006 |
| PTK2 | protein tyrosine kinase 2 | -0.0432573 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0432264 |
| WWC1 | WW and C2 domain containing 1 | -0.0427878 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0425147 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0422811 |
| EGR1 | early growth response 1 | -0.0420637 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0414963 |
| PGK1 | phosphoglycerate kinase 1 | -0.0413744 |
| RPS8 | ribosomal protein S8 | -0.0407611 |
| RPL23 | ribosomal protein L23 | -0.0403717 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0403199 |
| MKI67 | marker of proliferation Ki-67 | -0.0401353 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.039877 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0396732 |
| DIAPH2 | diaphanous-related formin 2 | -0.0396194 |
| DNM2 | dynamin 2 | -0.0389089 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0385096 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0381903 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.038171 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0378445 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376121 |
| ETV6 | ets variant 6 | -0.0375042 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0372432 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0370005 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0368733 |
| ANXA2 | annexin A2 | -0.03633 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0360728 |
| RRBP1 | ribosome binding protein 1 | -0.0360135 |
| RPS21 | ribosomal protein S21 | -0.035521 |
| KRT19 | keratin 19, type I | -0.0347718 |
| RPS24 | ribosomal protein S24 | -0.0342793 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0336744 |
| PRELID2 | PRELI domain containing 2 | -0.0335318 |
| ITGB4 | integrin, beta 4 | -0.0329681 |
| CA12 | carbonic anhydrase XII | -0.0329246 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0329219 |
| S100A6 | S100 calcium binding protein A6 | -0.0326793 |
| RPS12 | ribosomal protein S12 | -0.0323493 |
| RPS11 | ribosomal protein S11 | -0.0317251 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0314671 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0312076 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0311033 |
| KLF10 | Kruppel-like factor 10 | -0.0310961 |
| RPL27A | ribosomal protein L27a | -0.0298704 |
| KIAA0232 | KIAA0232 | -0.0295306 |
| RPS3 | ribosomal protein S3 | -0.0295302 |
| RPL34 | ribosomal protein L34 | -0.0294233 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0291659 |
| RPS5 | ribosomal protein S5 | -0.0290071 |
| ANXA11 | annexin A11 | -0.0289396 |
| RPLP2 | ribosomal protein, large, P2 | -0.0287855 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0287843 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0286933 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0284292 |
| RPL26 | ribosomal protein L26 | -0.0282682 |
| TMC5 | transmembrane channel-like 5 | -0.0281388 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.02791 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0278818 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0276316 |
| S100A10 | S100 calcium binding protein A10 | -0.0274906 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | -0.0274316 |
| EZR | ezrin | -0.0269968 |
| RPS13 | ribosomal protein S13 | -0.0269269 |
