| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mitoxantrone (dihydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mitoxantrone (dihydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV3 | neuron navigator 3 | 0.209167 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.162533 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.161228 |
| HDAC9 | histone deacetylase 9 | 0.160599 |
| FRMD6 | FERM domain containing 6 | 0.157841 |
| ZNF438 | zinc finger protein 438 | 0.149138 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.098904 |
| FRMD4A | FERM domain containing 4A | 0.0969483 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0813432 |
| JMJD1C | jumonji domain containing 1C | 0.0746958 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0673928 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0672515 |
| NABP1 | nucleic acid binding protein 1 | 0.0669265 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0628584 |
| INTS6 | integrator complex subunit 6 | 0.0620882 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0568649 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.056592 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0551244 |
| HMGA2 | high mobility group AT-hook 2 | 0.0538962 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0525011 |
| DGKI | diacylglycerol kinase, iota | 0.0501588 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.049535 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0494982 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.048998 |
| RAD51B | RAD51 paralog B | 0.0472357 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0471265 |
| NAV2 | neuron navigator 2 | 0.0457598 |
| BNC2 | basonuclin 2 | 0.0456535 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0447556 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0446148 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0441247 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0416149 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0404876 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0391194 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0387439 |
| SGMS2 | sphingomyelin synthase 2 | 0.0382068 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0382007 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.036722 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0363359 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0353252 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0345691 |
| RCOR1 | REST corepressor 1 | 0.0343244 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0341556 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.033403 |
| SETX | senataxin | 0.0324153 |
| FNIP1 | folliculin interacting protein 1 | 0.0318107 |
| RPL4 | ribosomal protein L4 | 0.0313414 |
| EXOC4 | exocyst complex component 4 | 0.0310913 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0309941 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0308731 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0308046 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0301961 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0298847 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0297165 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0295357 |
| GPATCH2L | G patch domain containing 2-like | 0.0292224 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0288072 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0285084 |
| TPM4 | tropomyosin 4 | 0.0281506 |
| PCNX4 | pecanex 4 | 0.0279551 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0270629 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0268237 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0263781 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0263731 |
| CUX1 | cut-like homeobox 1 | 0.0261072 |
| TENM3 | teneurin transmembrane protein 3 | 0.0253318 |
| EFNB2 | ephrin-B2 | 0.0250267 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0248264 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | 0.0247972 |
| VMP1 | vacuole membrane protein 1 | 0.0240368 |
| AK1 | adenylate kinase 1 | 0.0236775 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.023591 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0233438 |
| SQSTM1 | sequestosome 1 | 0.0231404 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0227313 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0224936 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0224866 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0224504 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0224465 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0222889 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0221385 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0220347 |
| FHIT | fragile histidine triad | 0.0220238 |
| CTBP2 | C-terminal binding protein 2 | 0.0217765 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0215614 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0212866 |
| CCDC91 | coiled-coil domain containing 91 | 0.0212349 |
| CUTC | cutC copper transporter | 0.0212132 |
| CORO1C | coronin, actin binding protein, 1C | 0.0211851 |
| EFL1 | elongation factor like GTPase 1 | 0.0211847 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0211356 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.021004 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0209748 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0209298 |
| ERBIN | erbb2 interacting protein | 0.0207097 |
| ANO6 | anoctamin 6 | 0.0206809 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0206431 |
| RPL13A | ribosomal protein L13a | 0.0205827 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.0204369 |
| PHF3 | PHD finger protein 3 | 0.0203335 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.0981774 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0957771 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0729169 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0651044 |
| MT2A | metallothionein 2A | -0.0539761 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0463855 |
| RPS19 | ribosomal protein S19 | -0.044595 |
| RPS21 | ribosomal protein S21 | -0.0441348 |
| B2M | beta-2-microglobulin | -0.0440659 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0436646 |
| RPS2 | ribosomal protein S2 | -0.0433676 |
| POTEF | POTE ankyrin domain family, member F | -0.042859 |
| STC1 | stanniocalcin 1 | -0.0426604 |
| RPLP0 | ribosomal protein, large, P0 | -0.0398257 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0396219 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0392336 |
| RBM39 | RNA binding motif protein 39 | -0.0387592 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0381415 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0370671 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0370016 |
| RPL7 | ribosomal protein L7 | -0.0368529 |
| RPS6 | ribosomal protein S6 | -0.0362366 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0344404 |
| RPL34 | ribosomal protein L34 | -0.0339651 |
| S100A9 | S100 calcium binding protein A9 | -0.0327406 |
| HLA-C | major histocompatibility complex, class I, C | -0.0315718 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0314068 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.030699 |
| RPL26 | ribosomal protein L26 | -0.0299906 |
| XPO1 | exportin 1 | -0.0296688 |
| RPL12 | ribosomal protein L12 | -0.0294396 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0287812 |
| RLF | rearranged L-myc fusion | -0.0284921 |
| S100A6 | S100 calcium binding protein A6 | -0.0284685 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | -0.0283395 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0279802 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0273342 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0264899 |
| NDRG1 | N-myc downstream regulated 1 | -0.0262795 |
| CDK17 | cyclin-dependent kinase 17 | -0.0260665 |
| HLA-B | major histocompatibility complex, class I, B | -0.0259969 |
| PTMA | prothymosin, alpha | -0.0256422 |
| RPL30 | ribosomal protein L30 | -0.0254396 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0253829 |
| PFN1 | profilin 1 | -0.0252668 |
| S100A2 | S100 calcium binding protein A2 | -0.0251613 |
| RPLP1 | ribosomal protein, large, P1 | -0.0251505 |
| CD68 | CD68 molecule | -0.0250468 |
| WDR43 | WD repeat domain 43 | -0.0249054 |
| UBC | ubiquitin C | -0.0246649 |
| XPC | xeroderma pigmentosum, complementation group C | -0.0245358 |
| RPS24 | ribosomal protein S24 | -0.0244572 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0241347 |
| MATR3 | matrin 3 | -0.0241024 |
| OGA | O-GlcNAcase | -0.0240711 |
| RPS4X | ribosomal protein S4, X-linked | -0.0240078 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0238126 |
| CCND2 | cyclin D2 | -0.0237613 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0233101 |
| RPL18 | ribosomal protein L18 | -0.0233081 |
| G0S2 | G0/G1 switch 2 | -0.023152 |
| RAB6A | RAB6A, member RAS oncogene family | -0.022884 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0228184 |
| FTL | ferritin, light polypeptide | -0.022694 |
| RPL23 | ribosomal protein L23 | -0.0224325 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0223782 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0220732 |
| NUP54 | nucleoporin 54kDa | -0.0219919 |
| RPL9 | ribosomal protein L9 | -0.0219572 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0218463 |
| RNF24 | ring finger protein 24 | -0.0217664 |
| ZNF37A | zinc finger protein 37A | -0.021695 |
| RPS5 | ribosomal protein S5 | -0.0215045 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0214671 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0211942 |
| RPL8 | ribosomal protein L8 | -0.0211738 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0208467 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0205533 |
| TRAM1 | translocation associated membrane protein 1 | -0.020486 |
| CSNK1E | casein kinase 1, epsilon | -0.0203823 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0203227 |
| BCL2L1 | BCL2-like 1 | -0.0201605 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0200745 |
| DSG2 | desmoglein 2 | -0.0200592 |
| S100A10 | S100 calcium binding protein A10 | -0.0198691 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0198107 |
| KDSR | 3-ketodihydrosphingosine reductase | -0.0198083 |
| NEMF | nuclear export mediator factor | -0.0197959 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0197753 |
| NUP58 | nucleoporin 58 | -0.0197549 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0197544 |
| MX1 | MX dynamin-like GTPase 1 | -0.0197185 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0196218 |
| RPL36 | ribosomal protein L36 | -0.0196056 |
| FOSL1 | FOS-like antigen 1 | -0.0195365 |
| ADAR | adenosine deaminase, RNA-specific | -0.01935 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.0193253 |
| BBX | bobby sox homolog (Drosophila) | -0.0191667 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0188893 |
| RPL32 | ribosomal protein L32 | -0.0185533 |
