Mitoxantrone Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A hydroxyanthraquinone that has formula C22H28N4O6. (Chemical Entities of Biological Interest Ontology, CHEBI_50729)
External Link http://ctdbase.org/detail.go?type=chem&acc=D008942
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Genes

181 genes/proteins interacting with the chemical Mitoxantrone from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACSL3 acyl-CoA synthetase long-chain family member 3
ACTG2 actin, gamma 2, smooth muscle, enteric
ADARB1 adenosine deaminase, RNA-specific, B1
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AHCYL1 adenosylhomocysteinase-like 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BACE2 beta-site APP-cleaving enzyme 2
BBX bobby sox homolog (Drosophila)
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
BMP7 bone morphogenetic protein 7
BST2 bone marrow stromal cell antigen 2
BTBD3 BTB (POZ) domain containing 3
C3ORF14 chromosome 3 open reading frame 14
CALR calreticulin
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCDC53 coiled-coil domain containing 53
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CELF2 CUGBP, Elav-like family member 2
CES2 carboxylesterase 2
CHRDL1 chordin-like 1
CKLF chemokine-like factor
CLNS1A chloride channel, nucleotide-sensitive, 1A
CLU clusterin
COCH cochlin
COL11A1 collagen, type XI, alpha 1
CPVL carboxypeptidase, vitellogenic-like
CREBL2 cAMP responsive element binding protein-like 2
CTH cystathionine gamma-lyase
CXADR coxsackie virus and adenovirus receptor
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DUSP4 dual specificity phosphatase 4
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EGR1 early growth response 1
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF5A eukaryotic translation initiation factor 5A
EN2 engrailed homeobox 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EVI5 ecotropic viral integration site 5
EXTL2 exostosin-like glycosyltransferase 2
FABP3 fatty acid binding protein 3, muscle and heart
FAM117A family with sequence similarity 117, member A
FAS Fas cell surface death receptor
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FNDC3A fibronectin type III domain containing 3A
FOXF2 forkhead box F2
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD2 frizzled class receptor 2
GAGE2A G antigen 2A
GAGE4 G antigen 4
GAGE6 G antigen 6
GAGE7 G antigen 7
GCH1 GTP cyclohydrolase 1
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H2AFX H2A histone family, member X
HDAC4 histone deacetylase 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HMG20B high mobility group 20B
HOXA5 homeobox A5
HSPA2 heat shock 70kDa protein 2
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFITM1 interferon induced transmembrane protein 1
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL13RA2 interleukin 13 receptor, alpha 2
IQGAP1 IQ motif containing GTPase activating protein 1
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LAMB1 laminin, beta 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LBH limb bud and heart development
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPG lipase, endothelial
LMNB1 lamin B1
MACROD1 MACRO domain containing 1
MAGEA6 melanoma antigen family A6
MAGED1 melanoma antigen family D1
MAGED4B melanoma antigen family D4B
MEST mesoderm specific transcript
MOCOS molybdenum cofactor sulfurase
MPC2 mitochondrial pyruvate carrier 2
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MXI1 MAX interactor 1, dimerization protein
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NAMPT nicotinamide phosphoribosyltransferase
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
NEFH neurofilament, heavy polypeptide
NID2 nidogen 2 (osteonidogen)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRIP1 nuclear receptor interacting protein 1
OXCT1 3-oxoacid CoA transferase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PARP1 poly (ADP-ribose) polymerase 1
PBX1 pre-B-cell leukemia homeobox 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDE8A phosphodiesterase 8A
PHGDH phosphoglycerate dehydrogenase
PLAGL1 pleiomorphic adenoma gene-like 1
PLAT plasminogen activator, tissue
PLCB4 phospholipase C, beta 4
PML promyelocytic leukemia
POMZP3 POM121 and ZP3 fusion
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PRDX2 peroxiredoxin 2
PRKCDBP protein kinase C, delta binding protein
PROSC proline synthetase co-transcribed homolog (bacterial)
PTPRE protein tyrosine phosphatase, receptor type, E
RARA retinoic acid receptor, alpha
RBBP8 retinoblastoma binding protein 8
RBM17 RNA binding motif protein 17
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RGS2 regulator of G-protein signaling 2
RUNX3 runt-related transcription factor 3
S100P S100 calcium binding protein P
SALL2 spalt-like transcription factor 2
SATB2 SATB homeobox 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCHIP1 schwannomin interacting protein 1
SDC2 syndecan 2
SEC31A SEC31 homolog A (S. cerevisiae)
SFN stratifin
SLC16A6 solute carrier family 16, member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SLMO2 slowmo homolog 2 (Drosophila)
SMAD2 SMAD family member 2
SORBS1 sorbin and SH3 domain containing 1
SPON1 spondin 1, extracellular matrix protein
SPON2 spondin 2, extracellular matrix protein
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TAGLN transgelin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TFF3 trefoil factor 3 (intestinal)
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TMEM47 transmembrane protein 47
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TPD52 tumor protein D52
TPM1 tropomyosin 1 (alpha)
TRIB1 tribbles pseudokinase 1
TRIM2 tripartite motif containing 2
UBL3 ubiquitin-like 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UQCRH ubiquinol-cytochrome c reductase hinge protein
UTRN utrophin
VCAN versican
WARS tryptophanyl-tRNA synthetase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZFAND1 zinc finger, AN1-type domain 1
ZSCAN18 zinc finger and SCAN domain containing 18