Mixed Lineage Leukemia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C3888194
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Genes

225 genes associated with the disease Mixed Lineage Leukemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AFDN afadin, adherens junction formation factor
AFF1 AF4/FMR2 family, member 1
AFF4 AF4/FMR2 family, member 4
AFM afamin
ALOX5 arachidonate 5-lipoxygenase
ANPEP alanyl (membrane) aminopeptidase
AR androgen receptor
ARF3 ADP-ribosylation factor 3
ARID1A AT rich interactive domain 1A (SWI-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARR3 arrestin 3, retinal (X-arrestin)
ASB2 ankyrin repeat and SOCS box containing 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ASRGL1 asparaginase like 1
ATM ATM serine/threonine kinase
BABAM2 BRISC and BRCA1 A complex member 2
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCOR BCL6 corepressor
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BEX2 brain expressed X-linked 2
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BRD4 bromodomain containing 4
CADM1 cell adhesion molecule 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CBFB core-binding factor, beta subunit
CBX8 chromobox homolog 8
CCND1 cyclin D1
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD19 CD19 molecule
CD24 CD24 molecule
CD33 CD33 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD44 CD44 molecule (Indian blood group)
CDK1 cyclin-dependent kinase 1
CDK6 cyclin-dependent kinase 6
CDK9 cyclin-dependent kinase 9
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHD4 chromodomain helicase DNA binding protein 4
CIB1 calcium and integrin binding 1 (calmyrin)
COMMD3-BMI1 COMMD3-BMI1 readthrough
CSF1R colony stimulating factor 1 receptor
CSPG4 chondroitin sulfate proteoglycan 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXADR coxsackie virus and adenovirus receptor
DCK deoxycytidine kinase
DHFR dihydrofolate reductase
DIAPH2 diaphanous-related formin 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOT1L DOT1-like histone H3K79 methyltransferase
DPY30 dpy-30 homolog (C. elegans)
EBP emopamil binding protein (sterol isomerase)
EGLN2 egl-9 family hypoxia-inducible factor 2
ELL elongation factor RNA polymerase II
EPHB2 EPH receptor B2
ESR1 estrogen receptor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FOXO3 forkhead box O3
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FRYL FRY-like
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GAL galanin/GMAP prepropeptide
GH1 growth hormone 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2A1L general transcription factor IIA, 1-like
GTF2A2 general transcription factor IIA, 2, 12kDa
HDAC1 histone deacetylase 1
HDAC9 histone deacetylase 9
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLF hepatic leukemia factor
HOXA10 homeobox A10
HOXA7 homeobox A7
HOXA9 homeobox A9
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL24 interleukin 24
KAT5 K(lysine) acetyltransferase 5
KDM1A lysine (K)-specific demethylase 1A
KDM2A lysine (K)-specific demethylase 2A
KDM4A lysine (K)-specific demethylase 4A
KDM4B lysine (K)-specific demethylase 4B
KDM5A lysine (K)-specific demethylase 5A
KDM6A lysine (K)-specific demethylase 6A
KDM6B lysine (K)-specific demethylase 6B
KDR kinase insert domain receptor
KIF2A kinesin heavy chain member 2A
KMT2A lysine (K)-specific methyltransferase 2A
KMT2B lysine (K)-specific methyltransferase 2B
KMT2C lysine (K)-specific methyltransferase 2C
KMT2D lysine (K)-specific methyltransferase 2D
KMT2E lysine (K)-specific methyltransferase 2E
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS4 lectin, galactoside-binding, soluble, 4
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
MBD2 methyl-CpG binding domain protein 2
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MEF2C myocyte enhancer factor 2C
MEIS1 Meis homeobox 1
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO5A myosin VA (heavy chain 12, myoxin)
NCAM1 neural cell adhesion molecule 1
NCKIPSD NCK interacting protein with SH3 domain
NEBL nebulette
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I3 nuclear receptor subfamily 1, group I, member 3
NSD1 nuclear receptor binding SET domain protein 1
NUP214 nucleoporin 214kDa
NUP98 nucleoporin 98kDa
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PARK2 parkin RBR E3 ubiquitin protein ligase
PBX3 pre-B-cell leukemia homeobox 3
PDC phosducin
PDLIM7 PDZ and LIM domain 7 (enigma)
PHC1 polyhomeotic homolog 1 (Drosophila)
PICALM phosphatidylinositol binding clathrin assembly protein
PKN1 protein kinase N1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PRDM9 PR domain containing 9
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PROM1 prominin 1
PSIP1 PC4 and SFRS1 interacting protein 1
RAB1B RAB1B, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
RARA retinoic acid receptor, alpha
RFC1 replication factor C (activator 1) 1, 145kDa
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUVBL2 RuvB-like AAA ATPase 2
S100A1 S100 calcium binding protein A1
S100A6 S100 calcium binding protein A6
S100B S100 calcium binding protein B
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SALL4 spalt-like transcription factor 4
SCT secretin
SEPT11 septin 11
SEPT2 septin 2
SEPT6 septin 6
SEPT9 septin 9
SET SET nuclear proto-oncogene
SETD1A SET domain containing 1A
SETD7 SET domain containing (lysine methyltransferase) 7
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SMAD3 SMAD family member 3
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNAP91 synaptosomal-associated protein, 91kDa
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SST somatostatin
STON1 stonin 1
STON1-GTF2A1L STON1-GTF2A1L readthrough
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TERF2IP telomeric repeat binding factor 2, interacting protein
TET1 tet methylcytosine dioxygenase 1
TGFB1 transforming growth factor, beta 1
TGIF1 TGFB-induced factor homeobox 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNF tumor necrosis factor
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TRIM13 tripartite motif containing 13
TTK TTK protein kinase
TXN thioredoxin
UBE2O ubiquitin-conjugating enzyme E2O
UHRF1 ubiquitin-like with PHD and ring finger domains 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WDR5 WD repeat domain 5
ZBTB16 zinc finger and BTB domain containing 16
ZC3H13 zinc finger CCCH-type containing 13
ZNF384 zinc finger protein 384
ZNF479 zinc finger protein 479
ZNF645 zinc finger protein 645