Monoclonal Gammopathy Of Undetermined Significance Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0026470
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Genes

204 genes associated with the disease Monoclonal Gammopathy Of Undetermined Significance in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALK anaplastic lymphoma receptor tyrosine kinase
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
AURKA aurora kinase A
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CANX calnexin
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCL20 chemokine (C-C motif) ligand 20
CCN1 cellular communication network factor 1
CCND1 cyclin D1
CCND3 cyclin D3
CCR4 chemokine (C-C motif) receptor 4
CCR7 chemokine (C-C motif) receptor 7
CD19 CD19 molecule
CD24 CD24 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD47 CD47 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN3 cyclin-dependent kinase inhibitor 3
CFH complement factor H
CKS1B CDC28 protein kinase regulatory subunit 1B
CLEC12A C-type lectin domain family 12, member A
COLEC10 collectin sub-family member 10 (C-type lectin)
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CSNK1A1 casein kinase 1, alpha 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DAP death-associated protein
DAPK1 death-associated protein kinase 1
DCC DCC netrin 1 receptor
DKC1 dyskeratosis congenita 1, dyskerin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAH11 dynein, axonemal, heavy chain 11
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ELL2 elongation factor, RNA polymerase II, 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPO erythropoietin
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
FAP fibroblast activation protein, alpha
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGF2 fibroblast growth factor 2 (basic)
FGFR3 fibroblast growth factor receptor 3
FLT3 fms-related tyrosine kinase 3
FOXP1 forkhead box P1
FOXP2 forkhead box P2
FOXP3 forkhead box P3
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GLI1 GLI family zinc finger 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPNMB glycoprotein (transmembrane) nmb
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRN granulin
GSTK1 glutathione S-transferase kappa 1
GSTP1 glutathione S-transferase pi 1
HAS1 hyaluronan synthase 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-B major histocompatibility complex, class I, B
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IFNA2 interferon, alpha 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGH immunoglobulin heavy locus
IGL immunoglobulin lambda locus
IGSF3 immunoglobulin superfamily, member 3
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL21 interleukin 21
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
JAG2 jagged 2
JAK2 Janus kinase 2
KDM1A lysine (K)-specific demethylase 1A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KL klotho
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
LCK LCK proto-oncogene, Src family tyrosine kinase
LIG3 ligase III, DNA, ATP-dependent
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LPL lipoprotein lipase
LRPPRC leucine-rich pentatricopeptide repeat containing
LTA lymphotoxin alpha
LY9 lymphocyte antigen 9
MAG myelin associated glycoprotein
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MRE11 MRE11 homolog, double strand break repair nuclease
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSC musculin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYOM2 myomesin 2
NBN nibrin
NCAM1 neural cell adhesion molecule 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NES nestin
NLRP2 NLR family, pyrin domain containing 2
NPC1 Niemann-Pick disease, type C1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSD2 nuclear receptor binding SET domain protein 2
OFD1 oral-facial-digital syndrome 1
PADI2 peptidyl arginine deiminase, type II
PARP1 poly (ADP-ribose) polymerase 1
PFDN5 prefoldin subunit 5
PLXNB2 plexin B2
PNMA2 paraneoplastic Ma antigen 2
PNP purine nucleoside phosphorylase
POT1 protection of telomeres 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRSS21 protease, serine, 21 (testisin)
PTCH1 patched 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PVR poliovirus receptor
RAD50 RAD50 homolog (S. cerevisiae)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RICTOR RPTOR independent companion of MTOR, complex 2
RPA1 replication protein A1, 70kDa
RUNX2 runt-related transcription factor 2
SDC1 syndecan 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SETBP1 SET binding protein 1
SFRP1 secreted frizzled-related protein 1
SFRP5 secreted frizzled-related protein 5
SLC12A9 solute carrier family 12, member 9
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMR3B submaxillary gland androgen regulated protein 3B
SOCS1 suppressor of cytokine signaling 1
SOST sclerostin
SSX1 synovial sarcoma, X breakpoint 1
SSX2 synovial sarcoma, X breakpoint 2
SSX2B synovial sarcoma, X breakpoint 2B
SSX4 synovial sarcoma, X breakpoint 4
SSX5 synovial sarcoma, X breakpoint 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STOML2 stomatin (EPB72)-like 2
SYK spleen tyrosine kinase
TBPL1 TBP-like 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP3 TIMP metallopeptidase inhibitor 3
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOM1 target of myb1 (chicken)
TP53 tumor protein p53
TP73 tumor protein p73
TTR transthyretin
ULK4 unc-51 like kinase 4
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
WWOX WW domain containing oxidoreductase
XPO1 exportin 1