Monocrotaline Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A pyrrolizidine alkaloid that has formula C16H23NO6. (Chemical Entities of Biological Interest Ontology, CHEBI_6980)
External Link http://ctdbase.org/detail.go?type=chem&acc=D016686
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Genes

35 genes/proteins interacting with the chemical Monocrotaline from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATM ATM serine/threonine kinase
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL16 chemokine (C-X-C motif) ligand 16
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
EDN1 endothelin 1
FOXO3 forkhead box O3
GFAP glial fibrillary acidic protein
GSTM1 glutathione S-transferase mu 1
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
LEP leptin
MKI67 marker of proliferation Ki-67
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD1 SMAD family member 1
TF transferrin
TNF tumor necrosis factor
TUBB3 tubulin, beta 3 class III
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A