| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Monocrotaline_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FBN1 | fibrillin 1 | 0.112181 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.111138 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0909281 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0832153 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0806311 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0545034 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0544771 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0539252 |
| GPC6 | glypican 6 | 0.0517455 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0480146 |
| UBC | ubiquitin C | 0.0422539 |
| ATP13A3 | ATPase type 13A3 | 0.0409811 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0390028 |
| AUTS2 | autism susceptibility candidate 2 | 0.0376383 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0372132 |
| SBF2 | SET binding factor 2 | 0.036088 |
| OGA | O-GlcNAcase | 0.035377 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0344334 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0341243 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0336071 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0332859 |
| NAV2 | neuron navigator 2 | 0.0321519 |
| SQSTM1 | sequestosome 1 | 0.0311619 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0310408 |
| PRELID2 | PRELI domain containing 2 | 0.0297239 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0283946 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0279989 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0272831 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.026979 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0267621 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0263191 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0262611 |
| COL1A2 | collagen, type I, alpha 2 | 0.0261438 |
| HELZ | helicase with zinc finger | 0.02607 |
| FMNL2 | formin-like 2 | 0.0258243 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0255162 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0255096 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0247203 |
| ZNF292 | zinc finger protein 292 | 0.0244993 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.024287 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0242674 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0241811 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0240869 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0240075 |
| DENND5A | DENN/MADD domain containing 5A | 0.0238983 |
| RUNX1 | runt-related transcription factor 1 | 0.0234016 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0231486 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0231152 |
| WTAP | Wilms tumor 1 associated protein | 0.0229215 |
| FNIP1 | folliculin interacting protein 1 | 0.0222751 |
| ARRDC3 | arrestin domain containing 3 | 0.0222731 |
| COL3A1 | collagen, type III, alpha 1 | 0.0222332 |
| SEPTIN9 | septin 9 | 0.0221942 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0218165 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0216033 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0215199 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0212861 |
| APP | amyloid beta (A4) precursor protein | 0.0205713 |
| LOXL2 | lysyl oxidase-like 2 | 0.020523 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.020497 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0202219 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0201739 |
| OPTN | optineurin | 0.0200392 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.019944 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0199095 |
| FLNB | filamin B, beta | 0.0198341 |
| STC1 | stanniocalcin 1 | 0.0197873 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0196539 |
| NBAS | neuroblastoma amplified sequence | 0.019546 |
| MEF2A | myocyte enhancer factor 2A | 0.0195133 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0194336 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0194182 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0192802 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0188286 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0187253 |
| DTNA | dystrobrevin, alpha | 0.0185607 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0184976 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.018317 |
| KIFAP3 | kinesin-associated protein 3 | 0.0182511 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0182173 |
| DST | dystonin | 0.0181394 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0180168 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0178774 |
| BBX | bobby sox homolog (Drosophila) | 0.0178173 |
| KIAA1217 | KIAA1217 | 0.0177112 |
| INSIG2 | insulin induced gene 2 | 0.0176266 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0176215 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0175802 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0175331 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0174387 |
| LDHA | lactate dehydrogenase A | 0.0173792 |
| ARFGEF3 | ARFGEF family member 3 | 0.0172813 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0171191 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0170067 |
| SETD5 | SET domain containing 5 | 0.0168834 |
| TAOK1 | TAO kinase 1 | 0.01688 |
| GOLGA4 | golgin A4 | 0.0168786 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0168128 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0167327 |
| COL5A2 | collagen, type V, alpha 2 | 0.0166597 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.211682 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.167447 |
| TMSB10 | thymosin beta 10 | -0.121997 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.100679 |
| PODXL | podocalyxin-like | -0.0967705 |
| FN1 | fibronectin 1 | -0.0784262 |
| CDH13 | cadherin 13 | -0.0694584 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0680057 |
| CSTB | cystatin B (stefin B) | -0.062506 |
| LMNA | lamin A/C | -0.0599642 |
| COL5A1 | collagen, type V, alpha 1 | -0.0591774 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0567632 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0554643 |
| S100A10 | S100 calcium binding protein A10 | -0.0516505 |
| HLA-B | major histocompatibility complex, class I, B | -0.0461009 |
| MAP1B | microtubule-associated protein 1B | -0.0453243 |
| PLAT | plasminogen activator, tissue | -0.0438498 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0421873 |
| S100A6 | S100 calcium binding protein A6 | -0.0420645 |
| PRSS23 | protease, serine, 23 | -0.039572 |
| SLC39A11 | solute carrier family 39, member 11 | -0.039014 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0385493 |
| LOX | lysyl oxidase | -0.0375469 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0368173 |
| CAVIN1 | caveolae associated protein 1 | -0.036592 |
| ASPH | aspartate beta-hydroxylase | -0.0352372 |
| MT2A | metallothionein 2A | -0.0349213 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0341679 |
| TPM4 | tropomyosin 4 | -0.0327098 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0322621 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0322149 |
| SUCNR1 | succinate receptor 1 | -0.0320638 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0312674 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0306751 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0292461 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0291711 |
| CALR | calreticulin | -0.0279392 |
| PTMA | prothymosin, alpha | -0.0278572 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0273258 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0263944 |
| EGFR | epidermal growth factor receptor | -0.0250279 |
| PLXNA2 | plexin A2 | -0.0248557 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0247649 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0246789 |
| AHNAK | AHNAK nucleoprotein | -0.0246409 |
| RIGI | RNA sensor RIG-I | -0.0241057 |
| LRRC17 | leucine rich repeat containing 17 | -0.0240375 |
| DCLK2 | doublecortin-like kinase 2 | -0.0228851 |
| IL7R | interleukin 7 receptor | -0.0228704 |
| RRBP1 | ribosome binding protein 1 | -0.0228663 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0227481 |
| CANX | calnexin | -0.0224726 |
| S100A11 | S100 calcium binding protein A11 | -0.0217279 |
| CCND1 | cyclin D1 | -0.0211968 |
| NAV1 | neuron navigator 1 | -0.0208541 |
| MT1X | metallothionein 1X | -0.0206557 |
| FTL | ferritin, light polypeptide | -0.020544 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0199953 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0194729 |
| HLA-C | major histocompatibility complex, class I, C | -0.0192786 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0192536 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0189721 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0181399 |
| MX2 | MX dynamin-like GTPase 2 | -0.0180431 |
| FMN2 | formin 2 | -0.0178186 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0176178 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0175827 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0174394 |
| ACTG1 | actin gamma 1 | -0.0174237 |
| EFNA5 | ephrin-A5 | -0.0174056 |
| TAGLN2 | transgelin 2 | -0.0172566 |
| KIAA1549L | KIAA1549-like | -0.0170056 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0168667 |
| PCDH7 | protocadherin 7 | -0.016856 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0165815 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0160927 |
| CYTH3 | cytohesin 3 | -0.0159161 |
| FRMD4A | FERM domain containing 4A | -0.0158029 |
| S100A4 | S100 calcium binding protein A4 | -0.0157597 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0156897 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0156438 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0156066 |
| KRT81 | keratin 81, type II | -0.0154664 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0154471 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0150897 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0150297 |
| B2M | beta-2-microglobulin | -0.014747 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0146251 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0145816 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0144585 |
| SYTL3 | synaptotagmin-like 3 | -0.0142695 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.014259 |
| ZNF217 | zinc finger protein 217 | -0.0141911 |
| COL1A1 | collagen, type I, alpha 1 | -0.0141111 |
| TPI1 | triosephosphate isomerase 1 | -0.0140397 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0139762 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.013941 |
| SEC61G | Sec61 gamma subunit | -0.0137944 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0137361 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0136014 |
