| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Monocrotaline_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.109479 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0988436 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0661363 |
| PGK1 | phosphoglycerate kinase 1 | 0.0600227 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0578682 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0576381 |
| XPO1 | exportin 1 | 0.0533968 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.050603 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0490472 |
| RPS24 | ribosomal protein S24 | 0.0483878 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0464932 |
| ANXA1 | annexin A1 | 0.0456828 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0443374 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0427786 |
| CLDN1 | claudin 1 | 0.0422021 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0420769 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.041847 |
| H1-0 | H1.0 linker histone | 0.0406444 |
| LMO7 | LIM domain 7 | 0.0399614 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0393388 |
| CCNL1 | cyclin L1 | 0.038926 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.037473 |
| YBX3 | Y box binding protein 3 | 0.0372635 |
| MGAT4C | MGAT4 family, member C | 0.0372593 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0372532 |
| TMEM123 | transmembrane protein 123 | 0.0367909 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0366012 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.036177 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0353257 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0353225 |
| TPX2 | TPX2, microtubule-associated | 0.0350928 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0347966 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0347555 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345869 |
| RPLP0 | ribosomal protein, large, P0 | 0.0338581 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0335177 |
| TPR | translocated promoter region, nuclear basket protein | 0.0334171 |
| THOC1 | THO complex 1 | 0.033352 |
| TMEM41B | transmembrane protein 41B | 0.0333366 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0332582 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0331808 |
| ZNF217 | zinc finger protein 217 | 0.033169 |
| ECT2 | epithelial cell transforming 2 | 0.0328202 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0320762 |
| KLF6 | Kruppel-like factor 6 | 0.0319824 |
| KIF5B | kinesin family member 5B | 0.0319664 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0313106 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.030749 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0307379 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0305595 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0303118 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0300126 |
| WDR43 | WD repeat domain 43 | 0.0290038 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0289063 |
| ZNF292 | zinc finger protein 292 | 0.0288748 |
| RPL41 | ribosomal protein L41 | 0.0287496 |
| RBM39 | RNA binding motif protein 39 | 0.0282148 |
| MATR3 | matrin 3 | 0.0281926 |
| SPAG9 | sperm associated antigen 9 | 0.028126 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 0.0279815 |
| WDR45B | WD repeat domain 45B | 0.0278363 |
| CD164 | CD164 molecule, sialomucin | 0.0271073 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0271018 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0268642 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0266629 |
| NEK7 | NIMA-related kinase 7 | 0.0266194 |
| TNPO1 | transportin 1 | 0.0265569 |
| PUM2 | pumilio RNA-binding family member 2 | 0.026259 |
| RPL35A | ribosomal protein L35a | 0.0262529 |
| TUT4 | terminal uridylyl transferase 4 | 0.0261904 |
| PNN | pinin, desmosome associated protein | 0.025893 |
| RLF | rearranged L-myc fusion | 0.0256419 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0255738 |
| TRIM33 | tripartite motif containing 33 | 0.025153 |
| MKI67 | marker of proliferation Ki-67 | 0.0250514 |
| GASK1B | golgi associated kinase 1B | 0.0249422 |
| TFRC | transferrin receptor | 0.0243724 |
| CLTC | clathrin, heavy chain (Hc) | 0.024332 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0243116 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.024311 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0242964 |
| SEPTIN7 | septin 7 | 0.0239008 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0238733 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0237994 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0236792 |
| RPS18 | ribosomal protein S18 | 0.023448 |
| YEATS2 | YEATS domain containing 2 | 0.0232261 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0230943 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.0230347 |
| ATP13A3 | ATPase type 13A3 | 0.0228079 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0227348 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.0224878 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0224866 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0224499 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0223278 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0222744 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0222594 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.022239 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0222307 |
| SNX13 | sorting nexin 13 | 0.0219512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232322 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.19787 |
| VIM | vimentin | -0.180113 |
| NLGN1 | neuroligin 1 | -0.160744 |
| HMGA2 | high mobility group AT-hook 2 | -0.121317 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0957796 |
| RPS27A | ribosomal protein S27a | -0.0924461 |
| TMSB10 | thymosin beta 10 | -0.0879094 |
| UBC | ubiquitin C | -0.075756 |
| POTEF | POTE ankyrin domain family, member F | -0.0754291 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0697639 |
| PCBP2 | poly(rC) binding protein 2 | -0.0683569 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0645118 |
| EGR1 | early growth response 1 | -0.0629318 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0606865 |
| ZNF804A | zinc finger protein 804A | -0.0590345 |
| YAP1 | Yes-associated protein 1 | -0.0586082 |
| MMP12 | matrix metallopeptidase 12 | -0.0584445 |
| PCDH7 | protocadherin 7 | -0.0573999 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0562107 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0541177 |
| EHBP1 | EH domain binding protein 1 | -0.0524297 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0516266 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.049824 |
| ACTG1 | actin gamma 1 | -0.0484891 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.048447 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0471558 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0469589 |
| NHSL1 | NHS-like 1 | -0.0435829 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0432063 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0413117 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.04095 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0407788 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0402115 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.038923 |
| TENM3 | teneurin transmembrane protein 3 | -0.0383758 |
| PFN1 | profilin 1 | -0.0379881 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0373915 |
| CMIP | c-Maf inducing protein | -0.037185 |
| INTS6 | integrator complex subunit 6 | -0.0369829 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0367888 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0366178 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0350473 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0347324 |
| TBCA | tubulin folding cofactor A | -0.0342465 |
| ZNF638 | zinc finger protein 638 | -0.0340941 |
| RHOA | ras homolog family member A | -0.0336551 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0326331 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0322793 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0321598 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0304969 |
| RASAL2 | RAS protein activator like 2 | -0.030088 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0299423 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0294147 |
| EDARADD | EDAR-associated death domain | -0.0293821 |
| RCOR1 | REST corepressor 1 | -0.0293733 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0292994 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0292529 |
| BRD2 | bromodomain containing 2 | -0.0290652 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0289526 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0289406 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.028396 |
| JMJD1C | jumonji domain containing 1C | -0.0283494 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0282739 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0278815 |
| PKM | pyruvate kinase, muscle | -0.0270599 |
| KMT2D | lysine (K)-specific methyltransferase 2D | -0.0262108 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0262058 |
| FTL | ferritin, light polypeptide | -0.0261147 |
| TUBA1B | tubulin, alpha 1b | -0.0257409 |
| NFIB | nuclear factor I/B | -0.0255491 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0250964 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0250258 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0249779 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0247175 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0240743 |
| RPL23 | ribosomal protein L23 | -0.0240399 |
| NEGR1 | neuronal growth regulator 1 | -0.0238274 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0236451 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0235426 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0232338 |
| SETX | senataxin | -0.0230636 |
| ASPH | aspartate beta-hydroxylase | -0.0229618 |
| EXOC6B | exocyst complex component 6B | -0.0227008 |
| ETV6 | ets variant 6 | -0.0224819 |
| CCN2 | cellular communication network factor 2 | -0.0222505 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.021451 |
| CEP112 | centrosomal protein 112kDa | -0.0213125 |
| WWOX | WW domain containing oxidoreductase | -0.021282 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0211868 |
| FOXM1 | forkhead box M1 | -0.0210382 |
| LATS2 | large tumor suppressor kinase 2 | -0.0209968 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0209541 |
| RPS15 | ribosomal protein S15 | -0.0208646 |
| BPTF | bromodomain PHD finger transcription factor | -0.0208519 |
| EGFR | epidermal growth factor receptor | -0.0205666 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0202273 |
| RPL3 | ribosomal protein L3 | -0.0202118 |
| RPS13 | ribosomal protein S13 | -0.0201101 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0199838 |
