| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Monocrotaline_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.268286 |
| FAM13A | family with sequence similarity 13, member A | 0.0709719 |
| HELZ | helicase with zinc finger | 0.0671852 |
| LPIN1 | lipin 1 | 0.0577979 |
| ZNF292 | zinc finger protein 292 | 0.0577314 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0538727 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0469489 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0452626 |
| OGA | O-GlcNAcase | 0.0441991 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0436942 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0417965 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0391018 |
| DSCAM | Down syndrome cell adhesion molecule | 0.038745 |
| MEF2A | myocyte enhancer factor 2A | 0.0360312 |
| ANXA2 | annexin A2 | 0.0349965 |
| XPO1 | exportin 1 | 0.0336023 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0331874 |
| MAP1B | microtubule-associated protein 1B | 0.0331148 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0325794 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.032237 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0321329 |
| PKM | pyruvate kinase, muscle | 0.0312335 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0310068 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0306319 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0303134 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0299649 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0295316 |
| WDR45B | WD repeat domain 45B | 0.0288751 |
| SPAG9 | sperm associated antigen 9 | 0.0287928 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.028686 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0281674 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0280825 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0279127 |
| SETD5 | SET domain containing 5 | 0.0277731 |
| HMGB2 | high mobility group box 2 | 0.0274505 |
| MATR3 | matrin 3 | 0.027093 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0270595 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0269277 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0266654 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0263743 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0259239 |
| SUCO | SUN domain containing ossification factor | 0.0253449 |
| SRP54 | signal recognition particle 54kDa | 0.0251184 |
| RNF145 | ring finger protein 145 | 0.025028 |
| NUP58 | nucleoporin 58 | 0.0247813 |
| CDC27 | cell division cycle 27 | 0.0243264 |
| RHOA | ras homolog family member A | 0.0243166 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.024256 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0242487 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0242304 |
| RTN4 | reticulon 4 | 0.0238908 |
| YEATS2 | YEATS domain containing 2 | 0.0237583 |
| SLMAP | sarcolemma associated protein | 0.0235487 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.023263 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.023081 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0229318 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0229015 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0227804 |
| NCKAP1 | NCK-associated protein 1 | 0.0227639 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0227612 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0223214 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0221531 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0220386 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0219837 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0219727 |
| YME1L1 | YME1-like 1 ATPase | 0.0219471 |
| GOLGA4 | golgin A4 | 0.0219191 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0217789 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0217526 |
| CASC3 | cancer susceptibility candidate 3 | 0.0215669 |
| YTHDC1 | YTH domain containing 1 | 0.0214388 |
| TOP1 | topoisomerase (DNA) I | 0.021294 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.021237 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0211082 |
| SEPTIN7 | septin 7 | 0.0208679 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0208322 |
| USP3 | ubiquitin specific peptidase 3 | 0.0207624 |
| QKI | QKI, KH domain containing, RNA binding | 0.0207402 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0207091 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0203988 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0203743 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0203243 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0203179 |
| COPS2 | COP9 signalosome subunit 2 | 0.0202625 |
| NEK7 | NIMA-related kinase 7 | 0.0201735 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0201098 |
| CCNY | cyclin Y | 0.0200808 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0200177 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0199949 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0197073 |
| AFDN | afadin, adherens junction formation factor | 0.0196186 |
| WDR36 | WD repeat domain 36 | 0.0195072 |
| UBC | ubiquitin C | 0.0194974 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0192242 |
| APP | amyloid beta (A4) precursor protein | 0.0191132 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0190524 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.018976 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0187356 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0186252 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0184489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.369802 |
| LSAMP | limbic system-associated membrane protein | -0.19431 |
| NRG1 | neuregulin 1 | -0.182366 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.176688 |
| VCL | vinculin | -0.122495 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.121347 |
| FMN1 | formin 1 | -0.0961609 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0917532 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0901768 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0810455 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0733583 |
| BPTF | bromodomain PHD finger transcription factor | -0.0724013 |
| ZNF804A | zinc finger protein 804A | -0.0681378 |
| RNF213 | ring finger protein 213 | -0.0627479 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0608031 |
| CRH | corticotropin releasing hormone | -0.0551974 |
| PRKCA | protein kinase C, alpha | -0.0537585 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0521803 |
| KLHL13 | kelch-like family member 13 | -0.0512423 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0510361 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0510257 |
| CADM2 | cell adhesion molecule 2 | -0.0508045 |
| PLAT | plasminogen activator, tissue | -0.0502793 |
| NREP | neuronal regeneration related protein | -0.0500049 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0494225 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0487079 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0484718 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0484349 |
| SYT1 | synaptotagmin I | -0.0480965 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0475994 |
| RAD51B | RAD51 paralog B | -0.0460458 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.045521 |
| COL1A1 | collagen, type I, alpha 1 | -0.0454965 |
| DNM3 | dynamin 3 | -0.043141 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0420731 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0419413 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0410933 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.040709 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0405728 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.040066 |
| TPM1 | tropomyosin 1 (alpha) | -0.0389153 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0384713 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0381253 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0376207 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0367952 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0367915 |
| TMSB10 | thymosin beta 10 | -0.0365483 |
| RPL35A | ribosomal protein L35a | -0.0365146 |
| ACTG1 | actin gamma 1 | -0.0362149 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0359179 |
| EGR1 | early growth response 1 | -0.035675 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0349201 |
| GLCCI1 | glucocorticoid induced 1 | -0.0346119 |
| CUX1 | cut-like homeobox 1 | -0.0336213 |
| VMP1 | vacuole membrane protein 1 | -0.0334984 |
| RPL23 | ribosomal protein L23 | -0.0333378 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0328587 |
| DACH2 | dachshund family transcription factor 2 | -0.0327738 |
| STK38L | serine/threonine kinase 38 like | -0.0324953 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0321199 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0315542 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0314409 |
| RPL34 | ribosomal protein L34 | -0.0308908 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0307571 |
| CNTN4 | contactin 4 | -0.0306025 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0302287 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.030199 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0301682 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0299583 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0295111 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0294435 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0292525 |
| EFNA5 | ephrin-A5 | -0.0291024 |
| FHIT | fragile histidine triad | -0.0284666 |
| TLE4 | transducin-like enhancer of split 4 | -0.0283823 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0283807 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0278319 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0278275 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0274485 |
| SIK2 | salt-inducible kinase 2 | -0.0274424 |
| FERMT2 | fermitin family member 2 | -0.0273614 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0272556 |
| PCDH9 | protocadherin 9 | -0.0269461 |
| PCDH15 | protocadherin-related 15 | -0.0268755 |
| MX2 | MX dynamin-like GTPase 2 | -0.0266196 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0266178 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0265807 |
| RIGI | RNA sensor RIG-I | -0.0265007 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0264805 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0262815 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0261027 |
| SP100 | SP100 nuclear antigen | -0.0255596 |
| DIAPH2 | diaphanous-related formin 2 | -0.0254782 |
| SMYD3 | SET and MYND domain containing 3 | -0.0252756 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0250013 |
| PCNX4 | pecanex 4 | -0.0248177 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0246981 |
| PDE10A | phosphodiesterase 10A | -0.0245462 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0245299 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0244875 |
