| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Monocrotaline_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.223355 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.107677 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0941363 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0851354 |
| AHNAK | AHNAK nucleoprotein | 0.0845982 |
| ITGA6 | integrin, alpha 6 | 0.0778581 |
| EZR | ezrin | 0.0776123 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0757342 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0753582 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0744343 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0739684 |
| EREG | epiregulin | 0.0736248 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0732362 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0729914 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0729263 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0713484 |
| PGK1 | phosphoglycerate kinase 1 | 0.0712995 |
| VCL | vinculin | 0.0709746 |
| DSPP | dentin sialophosphoprotein | 0.0708366 |
| NPSR1 | neuropeptide S receptor 1 | 0.0697858 |
| LMO7 | LIM domain 7 | 0.0673046 |
| ANXA2 | annexin A2 | 0.0670682 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0667919 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0630685 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0624077 |
| FAM13A | family with sequence similarity 13, member A | 0.0608546 |
| LDHA | lactate dehydrogenase A | 0.0598902 |
| PTMA | prothymosin, alpha | 0.0592133 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0574039 |
| MED13L | mediator complex subunit 13-like | 0.057132 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0544626 |
| FLNB | filamin B, beta | 0.0538381 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0493267 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0492667 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0489595 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0483857 |
| PARD3 | par-3 family cell polarity regulator | 0.0482479 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0478858 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0464525 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0449878 |
| PIGR | polymeric immunoglobulin receptor | 0.04483 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0447711 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.044763 |
| CCNY | cyclin Y | 0.0445786 |
| GPHN | gephyrin | 0.0445222 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0435409 |
| RBM39 | RNA binding motif protein 39 | 0.042713 |
| TPM4 | tropomyosin 4 | 0.0425284 |
| MYO5B | myosin VB | 0.0418613 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0416714 |
| FBXO11 | F-box protein 11 | 0.041591 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0413052 |
| CTBP2 | C-terminal binding protein 2 | 0.0412723 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0406772 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0396146 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0395806 |
| ACTN4 | actinin, alpha 4 | 0.0394195 |
| TMSB4X | thymosin beta 4, X-linked | 0.0393013 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0390716 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0390097 |
| ZNF292 | zinc finger protein 292 | 0.0383805 |
| APP | amyloid beta (A4) precursor protein | 0.0382321 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0379318 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0378524 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0368891 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0363258 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0363236 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0359904 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0356406 |
| KRT8 | keratin 8, type II | 0.0355871 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0354226 |
| FAT1 | FAT atypical cadherin 1 | 0.0353883 |
| ENO1 | enolase 1, (alpha) | 0.0353321 |
| FNBP1L | formin binding protein 1-like | 0.035036 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0349325 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0347532 |
| CD2AP | CD2-associated protein | 0.0344055 |
| SMYD3 | SET and MYND domain containing 3 | 0.0343737 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.034298 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0339446 |
| MYO1E | myosin IE | 0.0338468 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0338009 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0334244 |
| SERINC5 | serine incorporator 5 | 0.0332212 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0331553 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0328525 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0327571 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0327085 |
| ABI1 | abl-interactor 1 | 0.0326285 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0325889 |
| ANXA11 | annexin A11 | 0.0325314 |
| PRELID2 | PRELI domain containing 2 | 0.0325108 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0325083 |
| CUX1 | cut-like homeobox 1 | 0.0323163 |
| RLF | rearranged L-myc fusion | 0.0323125 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0318399 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0316941 |
| TFRC | transferrin receptor | 0.0316665 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0313678 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0313307 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.167767 |
| RPLP1 | ribosomal protein, large, P1 | -0.0784107 |
| RPS19 | ribosomal protein S19 | -0.0735995 |
| FTL | ferritin, light polypeptide | -0.0695184 |
| RPS12 | ribosomal protein S12 | -0.0656764 |
| RPLP2 | ribosomal protein, large, P2 | -0.0574409 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.056283 |
| S100P | S100 calcium binding protein P | -0.0550557 |
| RPS3 | ribosomal protein S3 | -0.050426 |
| RPL18 | ribosomal protein L18 | -0.0447637 |
| TNS4 | tensin 4 | -0.0425437 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0366415 |
| PFN1 | profilin 1 | -0.0364661 |
| MT2A | metallothionein 2A | -0.0353557 |
| RPL35A | ribosomal protein L35a | -0.0347774 |
| RPL37A | ribosomal protein L37a | -0.034734 |
| RPL36 | ribosomal protein L36 | -0.0338914 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0328264 |
| RPS13 | ribosomal protein S13 | -0.0315363 |
| RPL5 | ribosomal protein L5 | -0.0312961 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0308493 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0307374 |
| RPL19 | ribosomal protein L19 | -0.0302879 |
| RPS6 | ribosomal protein S6 | -0.0302582 |
| RPL26 | ribosomal protein L26 | -0.0296367 |
| RPL12 | ribosomal protein L12 | -0.0296207 |
| RPS16 | ribosomal protein S16 | -0.0272836 |
| MT1X | metallothionein 1X | -0.026838 |
| MT1E | metallothionein 1E | -0.0257507 |
| HMGA1 | high mobility group AT-hook 1 | -0.0253993 |
| RPL35 | ribosomal protein L35 | -0.0249948 |
| RPL23 | ribosomal protein L23 | -0.024733 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0240747 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0239064 |
| S100A6 | S100 calcium binding protein A6 | -0.0235859 |
| CLDN7 | claudin 7 | -0.0233191 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0231423 |
| RPL32 | ribosomal protein L32 | -0.0229759 |
| RPL21 | ribosomal protein L21 | -0.0212418 |
| RACK1 | receptor for activated C kinase 1 | -0.0209716 |
| RPL13A | ribosomal protein L13a | -0.0198201 |
| RPS21 | ribosomal protein S21 | -0.0191366 |
| GUK1 | guanylate kinase 1 | -0.0190395 |
| S100A14 | S100 calcium binding protein A14 | -0.0187231 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0185133 |
| RPL9 | ribosomal protein L9 | -0.0184685 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0184626 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0183262 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0182805 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0177337 |
| RPS14 | ribosomal protein S14 | -0.0177169 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0174619 |
| RPS17 | ribosomal protein S17 | -0.017329 |
| POTEF | POTE ankyrin domain family, member F | -0.0168362 |
| SFSWAP | splicing factor, suppressor of white-apricot family | -0.016601 |
| METTL15 | methyltransferase like 15 | -0.0164076 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0163129 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0159855 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0158727 |
| IGFL2 | IGF-like family member 2 | -0.0157797 |
| RNF43 | ring finger protein 43 | -0.0157021 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0155177 |
| GDF15 | growth differentiation factor 15 | -0.0152904 |
| RPL36A | ribosomal protein L36a | -0.0152683 |
| ZNF503 | zinc finger protein 503 | -0.0151124 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.014683 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -0.0143567 |
| SERF2 | small EDRK-rich factor 2 | -0.0143179 |
| ZFP36 | ZFP36 ring finger protein | -0.0139823 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0139821 |
| RPL36AL | ribosomal protein L36a-like | -0.0137858 |
| RPS8 | ribosomal protein S8 | -0.0137061 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0136345 |
| MT1G | metallothionein 1G | -0.013551 |
| S100A9 | S100 calcium binding protein A9 | -0.0133408 |
| RPS5 | ribosomal protein S5 | -0.0133119 |
| NOSTRIN | nitric oxide synthase trafficking | -0.0132218 |
| TMEM258 | transmembrane protein 258 | -0.0130444 |
| RPS4X | ribosomal protein S4, X-linked | -0.0128903 |
| RPL28 | ribosomal protein L28 | -0.0127569 |
| SEC61G | Sec61 gamma subunit | -0.0126208 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.01257 |
| CLDN4 | claudin 4 | -0.0123709 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0123258 |
| XPC | xeroderma pigmentosum, complementation group C | -0.0122381 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0120846 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0118569 |
| YBX1 | Y box binding protein 1 | -0.0116967 |
| LURAP1L | leucine rich adaptor protein 1-like | -0.0116452 |
| RPS27 | ribosomal protein S27 | -0.0116263 |
| TRIM24 | tripartite motif containing 24 | -0.0115765 |
| TBCA | tubulin folding cofactor A | -0.0114582 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0114008 |
| TJP3 | tight junction protein 3 | -0.0113929 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0113625 |
| GPX2 | glutathione peroxidase 2 | -0.0113203 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.011221 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0112201 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0111946 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0111844 |
