| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Monocrotaline_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.141316 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.123427 |
| TXNRD1 | thioredoxin reductase 1 | 0.0988488 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0853743 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0739151 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0646701 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0637601 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.062637 |
| FMNL2 | formin-like 2 | 0.0625419 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0605507 |
| SPAG9 | sperm associated antigen 9 | 0.0600554 |
| CAPRIN2 | caprin family member 2 | 0.0599826 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0596364 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0589758 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0583706 |
| RAI1 | retinoic acid induced 1 | 0.0576359 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.055314 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0523058 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0498739 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0497481 |
| USP34 | ubiquitin specific peptidase 34 | 0.049482 |
| NUP58 | nucleoporin 58 | 0.0492289 |
| EREG | epiregulin | 0.0490159 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0467821 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0455162 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0446145 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0424701 |
| JMJD1C | jumonji domain containing 1C | 0.0420772 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0419557 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0410802 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0402619 |
| TOP1 | topoisomerase (DNA) I | 0.0401833 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0401405 |
| FNIP1 | folliculin interacting protein 1 | 0.039761 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0389114 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0383232 |
| CENPF | centromere protein F, 350/400kDa | 0.0382827 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0381125 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0379845 |
| ZNF292 | zinc finger protein 292 | 0.0369453 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0368687 |
| RCOR1 | REST corepressor 1 | 0.0365586 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0364291 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0348726 |
| RTN4 | reticulon 4 | 0.0341457 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0335972 |
| LDHA | lactate dehydrogenase A | 0.0333868 |
| TMEM41B | transmembrane protein 41B | 0.0331949 |
| AHNAK | AHNAK nucleoprotein | 0.0326211 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0325128 |
| TSC22D2 | TSC22 domain family, member 2 | 0.032186 |
| PGK1 | phosphoglycerate kinase 1 | 0.032162 |
| OGA | O-GlcNAcase | 0.0320566 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0318071 |
| MYOF | myoferlin | 0.0317076 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0316493 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0314239 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0312538 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0310307 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0308243 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0305029 |
| UBC | ubiquitin C | 0.0304943 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0304912 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0304586 |
| RBM39 | RNA binding motif protein 39 | 0.0304356 |
| COG5 | component of oligomeric golgi complex 5 | 0.030365 |
| RPS18 | ribosomal protein S18 | 0.0298378 |
| WDR45B | WD repeat domain 45B | 0.0298316 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0298083 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0292672 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0290313 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0286748 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0286458 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0285874 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0279799 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0279299 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0277768 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0275903 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.027291 |
| NBAS | neuroblastoma amplified sequence | 0.0272706 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0269582 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0269464 |
| SRPK2 | SRSF protein kinase 2 | 0.0264643 |
| CLTC | clathrin, heavy chain (Hc) | 0.026202 |
| KIF1B | kinesin family member 1B | 0.0261166 |
| QKI | QKI, KH domain containing, RNA binding | 0.0261135 |
| RTTN | rotatin | 0.0258243 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0258017 |
| ARRDC3 | arrestin domain containing 3 | 0.0256312 |
| NEK10 | NIMA-related kinase 10 | 0.0255982 |
| WDR26 | WD repeat domain 26 | 0.0254487 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0253827 |
| RRM2 | ribonucleotide reductase M2 | 0.0252357 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0250762 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0246288 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0245854 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0245132 |
| NCKAP1 | NCK-associated protein 1 | 0.0242955 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0239359 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0235404 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.1858 |
| HLA-B | major histocompatibility complex, class I, B | -0.178012 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.144217 |
| CD44 | CD44 molecule (Indian blood group) | -0.0950814 |
| RIGI | RNA sensor RIG-I | -0.0834452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.083213 |
| MT2A | metallothionein 2A | -0.0756868 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.074794 |
| CADM2 | cell adhesion molecule 2 | -0.0709949 |
| RNF213 | ring finger protein 213 | -0.070943 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0703354 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.069488 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0659941 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0658766 |
| VIM | vimentin | -0.0629743 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0626412 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0620462 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0611049 |
| RPL35A | ribosomal protein L35a | -0.0573908 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0558748 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0542342 |
| RPL36 | ribosomal protein L36 | -0.0534448 |
| SP100 | SP100 nuclear antigen | -0.0511501 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.049536 |
| RPS19 | ribosomal protein S19 | -0.0493171 |
| B2M | beta-2-microglobulin | -0.049135 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0477195 |
| DPYD | dihydropyrimidine dehydrogenase | -0.045927 |
| PTMA | prothymosin, alpha | -0.0456768 |
| TRIM56 | tripartite motif containing 56 | -0.0456137 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0447003 |
| TNS3 | tensin 3 | -0.0433659 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0426742 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0423331 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0401321 |
| RPL36A | ribosomal protein L36a | -0.039411 |
| FTL | ferritin, light polypeptide | -0.0392369 |
| PDE10A | phosphodiesterase 10A | -0.0388531 |
| HLA-E | major histocompatibility complex, class I, E | -0.0385319 |
| RPS6 | ribosomal protein S6 | -0.0373846 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.036737 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.03658 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0365607 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0356363 |
| RPL12 | ribosomal protein L12 | -0.0354388 |
| RPL38 | ribosomal protein L38 | -0.0339419 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0331891 |
| RPL31 | ribosomal protein L31 | -0.0328662 |
| HLA-A | major histocompatibility complex, class I, A | -0.032859 |
| RPLP2 | ribosomal protein, large, P2 | -0.0327913 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0321043 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.031928 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0312358 |
| RPL37A | ribosomal protein L37a | -0.0305392 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0304268 |
| SMYD3 | SET and MYND domain containing 3 | -0.0301946 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0301555 |
| TMSB10 | thymosin beta 10 | -0.0293061 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0290764 |
| EFNA5 | ephrin-A5 | -0.028978 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0285798 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0285472 |
| CALD1 | caldesmon 1 | -0.0273546 |
| PLSCR1 | phospholipid scramblase 1 | -0.0270888 |
| RPS29 | ribosomal protein S29 | -0.0270549 |
| PMP22 | peripheral myelin protein 22 | -0.0268007 |
| ECE1 | endothelin converting enzyme 1 | -0.0266096 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0265874 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0264978 |
| RPS27 | ribosomal protein S27 | -0.0262245 |
| RPL28 | ribosomal protein L28 | -0.0259765 |
| RAD50 | RAD50 homolog (S. cerevisiae) | -0.0258732 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0253598 |
| DEK | DEK proto-oncogene | -0.0252334 |
| ENOSF1 | enolase superfamily member 1 | -0.0249972 |
| DNER | delta/notch-like EGF repeat containing | -0.0245797 |
| EPHA4 | EPH receptor A4 | -0.0245524 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0241808 |
| COL5A2 | collagen, type V, alpha 2 | -0.0240974 |
| EXOC4 | exocyst complex component 4 | -0.0238848 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.023754 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0236213 |
| RPLP1 | ribosomal protein, large, P1 | -0.0233767 |
| MT1E | metallothionein 1E | -0.0233729 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0230715 |
| HMGA1 | high mobility group AT-hook 1 | -0.0230714 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0228998 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0228357 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0224706 |
| RPL26 | ribosomal protein L26 | -0.0224162 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0223948 |
| DPH6 | diphthamine biosynthesis 6 | -0.0223725 |
| RPL37 | ribosomal protein L37 | -0.0222998 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0222773 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0222432 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0218407 |
| FERMT1 | fermitin family member 1 | -0.0216819 |
| RPL34 | ribosomal protein L34 | -0.0216696 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0215213 |
| RPS10 | ribosomal protein S10 | -0.0215046 |
